Atarashi Ryuichiro

アタラシリュウイチロウ | Atarashi Ryuichiro

Affiliation and department：
Job title： Professor
Other affiliations (4)：

University of Miyazaki Center for Animal Disease Control Division of Research & Inspection for Infectious Diseases
University of Miyazaki Center for Animal Disease Control Division of Research & Inspection for Infectious Diseases Professor
University of Miyazaki Department of Molecular Biology and Analytical Science
University of Miyazaki Department of Molecular Biology and Analytical Science Professor

Research field (1)： Neuroanatomy and physiology

Research keywords (4)：プリオン病, 神経変性疾患, 微生物学 , 微生物学 , 神経変性疾患 , プリオン病

Research theme for competitive and other funds (14)：

2023 - 2027 抗プリオン薬のプリオン株特異的有効性と薬剤耐性機構の解明
2020 - 2024 Does GPI-anchored modification promote the pathogenicity and transmissibility of alpha-synucleinopathies?
2019 - 2024 Elucidation of rotavirus interspecies transmission mechanism in Nepal and the role of adults in rotavirus circulation.
2020 - 2023 非定型BSE等動物プリオン病のヒトへの感染リスクの推定と低減に資する研究
2018 - 2022 ヒトプリオン持続感染培養細胞樹立による増幅機構の解明と新たな予防・治療法の創出

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Papers (61)：

Agriani Dini Pasiana, Hironori Miyata, Junji Chida, Hideyuki Hara, Morikazu Imamura, Ryuichiro Atarashi, Suehiro Sakaguchi. Central residues in prion protein PrPC are crucial for its conversion into the pathogenic isoform. Journal of Biological Chemistry. 2022. 298. 9. 102381-102381
Takatsuki H, Imamura M, Mori T, Atarashi R. Pentosan polysulfate induces low-level persistent prion infection keeping measurable seeding activity without PrP-res detection in Fukuoka-1 infected cell cultures. Sci Rep. 2022. 12. 1. 7923
Imamura M, Tabeta N, Iwamaru Y, Takatsuki H, Mori T, Atarashi R. Spontaneous generation of distinct prion variants with recombinant prion protein from a baculovirus-insect cell expression system. Biochem Biophys Res Commun. 2022. 613. 67-72
Keiji Uchiyama, Hideyuki Hara, Junji Chida, Agriani Dini Pasiana, Morikazu Imamura, Tsuyoshi Mori, Hanae Takatsuki, Ryuichiro Atarashi, Suehiro Sakaguchi. Ethanolamine Is a New Anti-Prion Compound. International Journal of Molecular Sciences. 2021. 22. 21. 11742-11742
Takayuki Fuse, Takehiro Nakagaki, Takujiro Homma, Hiroya Tange, Naohiro Yamaguchi, Ryuichiro Atarashi, Daisuke Ishibashi, Noriyuki Nishida. Dextran sulphate inhibits an association of prions with plasma membrane at the early phase of infection. Neuroscience research. 2021. 171. 34-40

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MISC (12)：

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Books (5)：

Lectures and oral presentations (28)：

Prion Disease Research Today
(The 96th annual meeting of Japanese Society for Bacteriology 2023)
ヒトグリオーマ細胞におけるプリオン感染動態の解析.
(第68回日本ウイルス学会学術集会 2021)
ペントサンポリサルフェートによるプリオン(Fukuoka-1株) 持続感染細胞における薬剤誘導性潜伏感染.
(第68回日本ウイルス学会学術集会 2021)
異常型プリオンタンパク無細胞増幅法(RT-QUIC法とPMCA法)を駆使したプリオン病病態機構の解明.
(第25回日本神経感染症学会総会・学術大会(基礎委員会セッション神経感染症の基礎) 2021)
スクレイピー感染ヒツジ脳には複数のプリオン株が混在している.
(九州微生物研究フォーラム2021 2021)

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Education (2)：

Professional career (1)：

Work history (10)：

2017/02/01 - 現在 University of Miyazaki Center for Animal Disease Control Division of Research & Inspection for Infectious Diseases Professor
2017/02/01 - 現在 University of Miyazaki Center for Animal Disease Control Division of Research & Inspection for Infectious Diseases
2016/10/01 - 現在 University of Miyazaki Frontier Science Research Center Department of Molecular Biology and Analytical Science
2016/04/01 - 現在 University of Miyazaki Frontier Science Research Center Department of Molecular Biology and Analytical Science Professor
2016/03/01 - 現在 University of Miyazaki Faculty of Madicine School of Madicine Infectious disease study course microbiological field Professor

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Committee career (9)：

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Awards (2)：

Association Membership(s) (5)：

日本神経感染症学会 , 日本ウイルス学会 , アジア太平洋プリオン研究会 , 日本生化学会 , 日本認知症学会

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