Rchr
J-GLOBAL ID：201201011040301947
Update date: May. 15, 2024
Ohtsuka Hokuto
Ohtsuka Hokuto
Homepage URL (1)：
http://www.ps.nagoya-u.ac.jp/lab_pages/microbio/aiba/index.html
Research field (1)：
Applied microbiology
Research theme for competitive and other funds (4)：
- 2021 - 2024 Analysis of cell miniaturization under sulfur depletion-Relationship between cyclin degradation and autophagy-
- 2019 - 2022 Hidden response to amino acid depletion -Ecl1 family gene-dependent extension of lifespan-
- 2016 - 2020 Analysis of mechanism of chronological lifespan extension by sulfur depletion in fission yeast
- 2014 - 2017 Analysis of Ecl1 family proteins that extends chronological lifespan
Papers (43)：
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Maekawa, Y, Matsui, K, Okamoto, K, Shimasaki, T, Ohtsuka, H, Tani, M, Ihara, K, Aiba, H. Identification of plb1 mutation that extends longevity via activating Sty1 MAPK in Schizosaccharomyces pombe. MOLECULAR GENETICS AND GENOMICS. 2024. 299. 1. 20
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Ohtsuka, H, Shimasaki, T, Aiba, H. Low-Molecular Weight Compounds that Extend the Chronological Lifespan of Yeasts, Saccharomyces cerevisiae, and Schizosaccharomyces pombe. ADVANCED BIOLOGY. 2024. e2400138
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Yoshiaki Kamada, Chiharu Umeda, Yukio Mukai, Hokuto Ohtsuka, Yoko Otsubo, Akira Yamashita, Takahiro Kosugi. Structure-based engineering of Tor complexes reveals that two types of yeast TORC1 produce distinct phenotypes. Journal of Cell Science. 2024. 137. 4
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Hokuto Ohtsuka, Yoko Otsubo, Takafumi Shimasaki, Akira Yamashita, Hirofumi Aiba. ecl family genes: Factors linking starvation and lifespan extension in Schizosaccharomyces pombe. Molecular Microbiology. 2023
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Hokuto Ohtsuka, Hiroki Sakata, Yuto Kitazaki, Masanobu Tada, Takafumi Shimasaki, Yoko Otsubo, Yasukichi Maekawa, Mikuto Kobayashi, Kazuki Imada, Akira Yamashita, et al. The ecl family gene ecl3+ is induced by phosphate starvation and contributes to sexual differentiation in fission yeast. Journal of Cell Science. 2023. 136. 6. jcs260759
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Books (1)：
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生物の寿命延長 ~老化・長寿命の基盤研究最前線~
(株)エヌ・ティー・エス 2022 ISBN:9784860437732
Lectures and oral presentations (122)：
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plb1遺伝子変異はSty1 MAPKの活性化を介して分裂酵母の寿命を延長する
(日本農芸化学会中部支部第196回例会 2023)
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分裂酵母の寿命延長因子Ecl1の糸状菌ホモログの機能解析
(日本農芸化学会中部支部第196回例会 2023)
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分裂酵母bgs1長寿命変異株の解析
(酵母遺伝学フォーラム第56回研究報告会 2023)
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ecl+ファミリー遺伝子の寿命延長効果とカゼインキナーゼ2(CK2)の関係について
(酵母遺伝学フォーラム第56回研究報告会 2023)
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Characterization of nnk1+ that regulates chronological lifespan in fission yeast.
(The 11 th International Fission Yeast Meeting 2023)
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Education (3)：
- 2009 - 2011 Nagoya University Graduate School of Bioagricultural Sciences
- 2007 - 2009 Nagoya University
- 2003 - 2007 Nagoya University
Work history (3)：
- 2012/04 - 現在 Nagoya University Graduate School of Pharmaceutical Sciences Department of Basic Medicinal Sciences Bioscience Assistant Professor
- 2011/05 - 2012/03 Japan Society for Promotion of Science Researcher
- 2009/04 - 2011/04 Japan Society for Promotion of Science Researcher
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