2016 - 2019 Physical studies for abnormal temperature increase detected by single-cell thermometry
2015 - 2018 心臓のミクロ熱力学:局所熱パルス法を用いた心臓の機能制御と熱物性測定
2015 - 2018 Elucidation of cardiac regulatory mechanisms by in vivo nano-imaging
2015 - 2018 Development of basic technologies for the treatment of heart disease by infra-red laser irradiation.
2014 - 2018 Development of core technologies for heart diagnostic imaging apparatus based on nanoanalysis
2014 - 2017 Development of a ratiometric fluorescent thermosensor sheet for non-invasive temperature mapping at single-cell level
2013 - 2016 Start-up of "Cell Thermodynamics": Studies on thermal properties and signaling in single living cells.
2011 - 2016 Elucidation of the heart's functions by in vivo nano-imaging
2010 - 2016 Regulatory Basis of Biomotility: Chemo-mechanical Feedback Loop
2011 - 2015 Elucidation of cardiac excitation-contraction coupling by in vivo nano-imaging
2009 - 2012 単一細胞内温度変化イメージング : 新しい細胞機能研究法の開発と応用
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Papers (43)：
Fuyu Kobirumaki-Shimozawa, Kotaro Oyama, Tomohiro Nakanishi, Shin’ichi Ishiwata, Norio Fukuda. Asynchronous movement of sarcomeres in myocardium under living conditions: role of titin. Frontiers in Physiology. 2024. 15
Shuya Ishii, Kotaro Oyama, Fuyu Kobirumaki-Shimozawa, Tomohiro Nakanishi, Naoya Nakahara, Madoka Suzuki, Shin’ichi Ishiwata, Norio Fukuda. Myosin and tropomyosin-troponin complementarily regulate thermal activation of muscles. Journal of General Physiology. 2023. 155. 12
Madoka Suzuki, Chujie Liu, Kotaro Oyama, Toshiko Yamazawa. Trans-scale thermal signaling in biological systems. The Journal of Biochemistry. 2023
Madoka Suzuki, Kotaro Oyama, Toshiko Yamazawa. Hybrid Biophysics: Interdisciplinary approaches for trans-scale analysis of organism-environment interactions. Biophysics and Physicobiology. 2023
Atsushi Kimura, Tadashi Arai, Miho Ueno, Kotaro Oyama, Hao Yu, Shinichi Yamashita, Yudai Otome, Mitsumasa Taguchi. Synthesis of Small Peptide Nanogels Using Radiation Crosslinking as a Platform for Nano-Imaging Agents for Pancreatic Cancer Diagnosis. Pharmaceutics. 2022. 14. 11. 2400-2400
