Fujiyama Tomoyuki

Fujiyama Tomoyuki | Fujiyama Tomoyuki

Affiliation and department：
Job title： Assistant Professor
Other affiliations (1)：

National Center of Neurology and Psychiatry National Institute of Neuroscience

Homepage URL (1)： https://wpi-iiis.tsukuba.ac.jp/

Research field (2)： Neuroscience - general , Neuroscience - general

Research keywords (7)： cerebellum , Sexual differentiation , CRISPR , sleep , hypothalamus , cochlear nucleus , neural development

Research theme for competitive and other funds (10)：

2022 - 2025 Study for Mechanisms of Volatile Anesthesia via Functional Alteration of NALCN Channel
2023 - 2024 International collaborative research network focused on the innovative interactome analysis in vivo BioID
2020 - 2023 A biological study of the neural and molecular basis for REM sleep regulation by NALCN
2019 - 2022 19H03142
2018 - 2020 18K14811

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Papers (23)：

Ayaka Nakai, Mitsuaki Kashiwagi, Tomoyuki Fujiyama, Kanako Iwasaki, Arisa Hirano, Hiromasa Funato, Masashi Yanagisawa, Takeshi Sakurai, Yu Hayashi. Crucial role of TFAP2B in the nervous system for regulating NREM sleep. Molecular brain. 2024. 17. 1. 13-13
Fuyuki Asano, Staci J Kim, Tomoyuki Fujiyama, Chika Miyoshi, Noriko Hotta-Hirashima, Nodoka Asama, Kanako Iwasaki, Miyo Kakizaki, Seiya Mizuno, Michihiro Mieda, et al. SIK3-HDAC4 in the suprachiasmatic nucleus regulates the timing of arousal at the dark onset and circadian period in mice. Proceedings of the National Academy of Sciences of the United States of America. 2023. 120. 11. e2218209120
Staci J Kim, Noriko Hotta-Hirashima, Fuyuki Asano, Tomohiro Kitazono, Kanako Iwasaki, Shinya Nakata, Haruna Komiya, Nodoka Asama, Taeko Matsuoka, Tomoyuki Fujiyama, et al. Kinase signalling in excitatory neurons regulates sleep quantity and depth. Nature. 2022. 612. 7940. 512-518
Tomoyuki Fujiyama, Henri Takenaka, Fuyuki Asano, Kazuya Miyanishi, Noriko Hotta-Hirashima, Yukiko Ishikawa, Satomi Kanno, Patricia Seoane-Collazo, Hideki Miwa, Mikio Hoshino, et al. Mice Lacking Cerebellar Cortex and Related Structures Show a Decrease in Slow-Wave Activity With Normal Non-REM Sleep Amount and Sleep Homeostasis. Frontiers in Behavioral Neuroscience. 2022. 16. 910461-910461
Jinhwan Choi, Staci J Kim, Tomoyuki Fujiyama, Chika Miyoshi, Minjeong Park, Haruka Suzuki-Abe, Masashi Yanagisawa, Hiromasa Funato. The Role of Reproductive Hormones in Sex Differences in Sleep Homeostasis and Arousal Response in Mice. Frontiers in neuroscience. 2021. 15. 739236-739236

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MISC (3)：

Tomoyuki Fujiyama, Mai Nagaoka, Yuchio Yanagawa, Mark Magnuson, Kunihiko Obata, Yoshiya Kawaguchi, Yo-ichi Nabeshima, Mikio Hoshino. Genetic studies on the development and function of the hypothalamus using Ptf1a-Cre & -flox knock-in mice. NEUROSCIENCE RESEARCH. 2011. 71. E331-E332
Tomoyuki Fujiyama, Mayumi Yamada, Mami Terao, Toshio Terashima, Yuchio Yanagawa, Kunihiko Obata, Yoshiya Kawaguchi, Yo-Ichi Nabeshima, Mikio Hoshino. Genetic studies on the development of cochlear nucleus neurons using Ptf1a-cre knock-in mice. NEUROSCIENCE RESEARCH. 2008. 61. S86-S86
Mayumi Yamada, Mami Terao, Toshio Terashima, Tomoyuki Fujiyama, Yoshiya Kawaguchi, Yo-Ichi Nabeshima, Mikio Hoshino. Origin of climbing fiber neurons and their developmental dependence on Ptf1a. NEUROSCIENCE RESEARCH. 2007. 58. S200-S200

Books (1)：

「眠気」の生化学的な実体に迫るー睡眠要求を規定するリン酸化タンパク質群の同定
実験医学 2019年1月号 Vol.37 No.1 「なぜ、いま核酸医薬なのか」

Lectures and oral presentations (7)：

NALCN in the forebrain and pons-medulla regions have distinct roles in REM sleep regulation
(The 73th JPS Hokubu 2022)
発生期視床下部に発現する遺伝子と脳の性分化
(名古屋大学高等研究院・若手新分野創成ワークショップ「脳を知り、疾患を理解する」)
How the mammalian brain sexually differentiates - hypothalamic Ptf1a confers the competence
(Japanese Society for Behavioral Neuroendocrinology 29th Meeting 2018)
Forebrain Ptf1a is required for sexual differentiation of the brain
(2018 Joint Meeting between The Neurodevelopmental Biology Section of The Korean Society for Molecular and Cellular Biology and Japanese Developmental Neuroscientists 2018)
Forebrain Ptf1a is required for sexual differentiation of the brain
(22nd Biennial Meeting of the International Society of Developmental Neuroscience 2018)

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Education (4)：

2009 - 2012 JSPS Research Fellowship (DC1)
2008 - 2012 Kyoto University Graduate School of Medicine
2006 - 2008 Kyoto University Graduate School of Biostudies
2002 - 2006 Kyushu University Dept of Biology

Professional career (1)：

Ph.D. (Kyoto Univ.)

Work history (6)：

2023/09 - 現在 Duke University School of Medicine Cell Biology, Scott Soderling Lab Visiting Researcher
2018/10 - 現在 Univ of Tsukuba WPI-IIIS, Yanagisawa/Funato Lab Assistant Professor
2014/04 - 2018/09 Univ of Tsukuba WPI-IIIS, Yanagisawa/Funato Lab Researcher
2015/04 - 2018/03 JSPS Research Fellowship (PD)
2013/09 - 2014/03 Univ of Tsukuba Mol Behav Neurosci Researcher

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Awards (5)：

2022 - TRiSTAR Fellows, Strategic Professional Development Program for Young Researchers, MEXT
2021 - Young Faculty Award, University of Tsukuba
2020 - The Japanese Teratology Society Poster Prize
2019 - National Institute of Neuroscience, NCNP, First Runner-Up Paper of the Year Award
2018 - International Society for Developmental Neuroscience, Best Poster Award

Association Membership(s) (6)：

Society for Neuroscience , THE JAPAN NEUROSCIENCE SOCIETY , THE MOLECULAR BIOLOGY SOCIETY OF JAPAN , The Japanese Pharmacological Society , The Japanese Teratology Society , THE JAPANESE SOCIETY OF TOXICOLOGY

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