Rchr
J-GLOBAL ID:201201026868621950
Update date: Nov. 18, 2024
ICHIRO KAWAHATA
カワハタ イチロウ | ICHIRO KAWAHATA
Affiliation and department:
Job title:
Associate Professor
Homepage URL (2):
https://plaza.umin.ac.jp/brain/
,
https://plaza.umin.ac.jp/brain/index(en).html
Research field (5):
Pharmacology
, Neuroscience - general
, Pathobiochemistry
, Neuroanatomy and physiology
, Pharmaceuticals - health and biochemistry
Research keywords (20):
Parkinson's disease
, Dementia with Lewy Bodies
, tyrosine hydroxylase
, Alzheimer's disease
, Dystonia
, diagnostic technology
, biomarker
, fatty acid-binding protein
, α-synuclein
, dopamine receptor
, aging
, Nurr1
, dopaminerigc neuron
, serum responsive factor
, cranial nerve disease
, catecholamine
, dopamine
, V-1/CP complex
, sinensetin
, nobiletin
Research theme for competitive and other funds (21):
- 2024 - 2027 FABP3 リガンドを用いた世界初のレビー小体病根本治療薬の開発
- 2022 - 2025 Novel Drug Discovery and Therapeutics Development for Lewy Body Disease Targeting Fatty Acid-Binding Proteins
- 2023 - 2025 パーキンソン病認知症およびレビー小体型認知症による神経変性の根本治療薬開発
- 2022 - 2025 パーキンソン病の新規治療戦略と超早期予測技術の開発
- 2023 - 2024 神経変性疾患関連タンパク質α-synucleinの神経細胞への沈着を防止する創薬ペプチドの合理的改変と実験的検証
- 2021 - 2024 ドパミン受容体モデュレーターを介したニコチン依存形成と治療薬開発
- 2022 - 2023 パーキンソン病認知症およびレビー小体型認知症による神経変性の根本治療薬開発
- 2020 - 2023 パーキンソン病の新規治療戦略と超早期予測技術の開発
- 2019 - 2022 Development of Therapeutics for Mitochondrial Impairment in Autism Spectrum Disorders
- 2019 - 2022 Analysis of human-specific regulation of neural function by V-1/CP complex and its therapeutic application for aging-related disorders
- 2021 - 2022 インテリジェント・コスモス学術振興財団 国際学会助成
- 2020 - 2022 Research on the molecular mechanism of α-synuclein propagation in synucleinopathies
- 2020 - 2022 小児性ジストニアの分子遺伝学的解析と新規創薬標的の探索
- 2018 - 2020 新規V-1/CP複合体を標的とする漢方および天然化合物を用いたアルツハイマー病・パーキンソン病根本治療の創薬研究
- 2017 - 2020 新規V-1/CP複合体を標的としたニコチン性アセチルコリン受容体シグナル伝達による中脳ドパミン作動性神経の新たな機能制御機構
- 2016 - 2019 Development of fundamental therapy for dopamine-related disorders targetting novel protein complex V-1/CP
- 2018 - Intelligent Cosmos Academic Foundation
- 2016 - アクチン細胞骨格制御因子V-1/CPタンパク質相互作用によるドパミン作動性神経の保護・活性化促進機構の解明
- 2015 - 新規アクチン重合制御因子V-1/CP複合体による統合的筋骨格安定化機構の解明および創薬ターゲット応用
- 2013 - 2015 Therapeutic application of V-1 gene-dependent mechanism to Parkinson's disease potentiating dopamine biosynthesis coupled with actin dynamics
- 2011 - 2012 Development of novel therapy for Parkinson's disease targeted toV-1 regulatory system of dopamine biosynthesis
Show all
Papers (95):
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Gofarana Wilar, Cecep Suhandi, Kohji Fukunaga, Ichiro Kawahata. Efficacy and safety of tofacitinib on COVID-19 patients: A systematic review and meta-analysis. Heliyon. 2024. 10. 19. e38229
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Tomoki Sekimori, Kohji Fukunaga, David I Finkelstein, Ichiro Kawahata. Advances in Blood Biomarkers and Diagnosis Approaches for Neurodegenerative Dementias and Related Diseases. Journal of integrative neuroscience. 2024. 23. 10. 188-188
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Ichiro Kawahata, David I. Finkelstein, Kohji Fukunaga. Dopamine D1-D5 Receptors in Brain Nuclei: Implications for Health and Disease. Receptors. 2024
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Tomoki Sekimori, Kohji Fukunaga, Hideki Oizumi, Toru Baba, Tomoko Totsune, Atsushi Takeda, Takuya Sasaki, Ichiro Kawahata. FABP2 is Involved in Intestinal α-Synuclein Pathologies. Journal of Integrative Neuroscience. 2024. 23. 2. 44-44
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Gofarana Wilar, Cecep Suhandi, Nasrul Wathoni, Kohji Fukunaga, Ichiro Kawahata. Nanoparticle-Based Drug Delivery Systems Enhance Treatment of Cognitive Defects. International journal of nanomedicine. 2024. 19. 11357-11378
more...
MISC (83):
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Ichiro Kawahata, Atsushi Takeda, Kohji Fukunaga. Development of early prediction and discriminating techniques for Lewy body diseases. Folia Pharmacologica Japonica. 2024. 159. 1. 2-5
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Ichiro Kawahata, Masahiro Nagai. Preface. Folia Pharmacologica Japonica. 2024. 159. 1. 1-1
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福永浩司, 西哲郎, 福永康太, 川畑伊知郎. 人間ドックで有効な認知症リスクの血液中バイオマーカーの開発. 人間ドック. 2023. 38. 2
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川畑 伊知郎, 福永 浩司. シヌクレイノパチーを予防可能な新規ペプチド治療薬の創製-Development of Novel Peptide Therapeutics to Prevent α-synucleinopathies-特集 注目される創薬研究と新技術開発. 化學工業. 2023. 74. 1. 41-46
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福永 浩司, 川畑 伊知郎. 認知症のリスクを検知する血液中バイオマーカーの開発. 人間ドック. 2022. 37. 2. 375-375
more...
Patents (14):
Books (4):
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シヌクレイノパチーを予防可能な新規ペプチド治療薬の創製
化学工業 2022
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Endocytosis of dopamine receptor: signaling in brain
Elsevier 2022
-
Development of Novel Medium-molecular Therapeutics for Lewy Body Disease
2022
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医療・診断をめざす先端バイオテクノロジー
工学図書 2009 ISBN:9784769204909
Lectures and oral presentations (99):
-
瀬川病の新たな治療戦略と創薬への挑戦
(第38回 日本大脳基底核研究会 2024)
-
瀬川病の全国調査 第2報 -成人症例の治療について-
(第18回 日本パーキンソン病・運動障害疾患学会)
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瀬川病の全国調査 第1報 -小児期発症と成人発症の特徴-
(第18回 日本パーキンソン病・運動障害疾患学会)
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Development of novel drugs and early diagnostic techniques for Lewy body diseases targeting fatty acid-binding proteins
(18th International Conference on Alzheimer’s & Parkinson’s Diseases 2024)
-
脂肪酸結合タンパク質3(FABP3)欠損による内側前頭前野における遺伝子発現の変化
(第97回日本薬理学会年会 2023)
more...
Education (1):
- 2006 - 2009 Tokyo Institute of Technology Department of Bioscience and Biotechnology Molecular Life Science
Professional career (2):
- Ph.D. (Science) (Tokyo Institute of Technology)
- Ph.D. (Pharmaceutical Science) (Tohoku University)
Committee career (7):
Awards (11):
- 2023/09 - 東北大学 東北大学大学院薬学研究科長賞
- 2022/07 - 東北大学 東北大学大学院薬学研究科長賞
- 2021/12 - JSNP Excellent Presentation Award for AsCNP
- 2021/03 - The Japanese Pharmacological Society Young Researcher's Award
- 2020/12 - International Conference on Protein Phosphatase The Young Investigator Award
- 2020/07 - Tohoku University Dean Award, Tohoku University
- 2019/11 - Japan Brain Science Society Outstanding Research Award
- 2018/07 - Asia Pacific Society for Biology and Medical Sciences Outstanding Research Award
- 2018/05 - Intelligent Cosmos Academic Foundation The 17th Intelligent Cosmos Prize
- 2014/03 - The Japanese Pharmacological Society The Best Presentation Award
- 2007/11 - International Symposium on Dopaminergic and Nondopaminergic Mechanisms in Parkinson's Disease INPD The Best Poster Award
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Association Membership(s) (10):
日本生薬学会
, Society for Neuroscience
, 日本薬学会
, Japanese Pharmacological Society
, Japanese Biochemical Society
, Japan Neuroscience Society
, 日本神経学会
, 日本神経化学会
, THE JAPANESE SOCIETY OF NEUROPSYCHOPHARMACOLOGY
, JAPAN BRAIN SCIENCE SOCIETY
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