2022 - 2025 Examination of the effect of combination therapy of galectin-9 and epigallocatechin gallate on hepatocellular carcinoma
2020 - 2024 腸肝軸に着目したNASHの新たな診断方法と創薬についての基礎的研究
2017 - 2020 Identification of microRNAs that regulate Galectin 9 to suppress nonalcoholic steatohepatitis progression
2016 - 2019 Basic study on treatment of hepatocellular carcinoma targetted of Gal-9 exosomes
2013 - 2016 Anti-tumor effect of galectin 9 in hepatocell carcinoma:Basic study
2012 - 2015 MicroRNA of the non-alcoholic steato-hepatitis
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Papers (345):
Kyoko Oura, Asahiro Morishita, Rie Yano, Takushi Manabe, Kei Takuma, Mai Nakahara, Tomoko Tadokoro, Koji Fujita, Shima Mimura, Joji Tani, et al. Circulating miR-485-3p as a biomarker for VEGF-associated therapeutic response to atezolizumab plus bevacizumab in hepatocellular carcinoma. Journal of gastroenterology. 2025
Takushi Manabe, Chikara Ogawa, Takashi Tamada, Naoki Yoshioka, Takehiro Akahane, Hideki Fujii, Hirotaka Arai, Kei Takuma, Mai Nakahara, Kyoko Oura, et al. Usefulness of Repeated Lusutrombopag Administration in Clinical Practice and its Correlation with the Simulation Software-Predicted Platelet Count: A Multicenter Study. Internal medicine (Tokyo, Japan). 2025
Tomoko Aoki, Masatoshi Kudo, Naoshi Nishida, Kazuomi Ueshima, Kaoru Tsuchiya, Toshifumi Tada, Masahiro Morita, Hirokazu Chishina, Masahiro Takita, Satoru Hagiwara, et al. Proposal of discontinuation criteria of atezolizumab plus bevacizumab after curative conversion therapy for unresectable early-to-intermediate-stage hepatocellular carcinoma: a multicenter proof-of-concept study. Journal of gastroenterology. 2025
Norikazu Tanabe, Issei Saeki, Kenji Yamaoka, Tomokazu Kawaoka, Tetsu Tomonari, Joji Tani, Takeshi Terashima, Yusuke Kawamura, Shiro Oka, Tetsuji Takayama, et al. Efficacy of Lenvatinib and Atezolizumab Bevacizumab Combination Therapy in Patients With Combined Hepatocellular-cholangiocarcinoma. Anticancer research. 2025. 45. 3. 1117-1125
Shigeo Shimose, Issei Saeki, Takanori Ito, Yasuto Takeuchi, Joji Tani, Tetsu Tomonari, Ryu Sasaki, Kyo Sasaki, Satoru Kakizaki, Takeshi Hatanaka, et al. The benefit of conversion therapy for patients with unresectable hepatocellular carcinoma receiving atezolizumab plus bevacizumab using newly established oncological resectability criteria in Japan. Hepatology international. 2025