SAKAGUCHI Masanori

Sakaguchi Masanori | SAKAGUCHI Masanori

Affiliation and department：
Job title： Associate Professor
Homepage URL (1)： https://sakaguchi-lab.org/

Research field (1)： Cognitive neuroscience

Research keywords (7)：新生ニューロン , 記憶 , 睡眠 , 海馬 , 生体脳イメージング , 光遺伝学 , 深層学習

Research theme for competitive and other funds (23)：

2022 - 2029 Deciphering the mysteries of sleep:creating a global network of sleep neurobiologists
2023 - 2026 レム睡眠中に恐怖記憶が再想起する意義の解明
2022 - 2025 Molecular Research and Treatment of Fear Memory in PTSD
2020 - 2025 睡眠と冬眠:2つの「眠り」の解明と操作が拓く新世代医療の展開
2021 - 2024 Study of the principles of consciousness

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Papers (46)：

Pablo Vergara, Yuteng Wang, Sakthivel Srinivasan, Yoan Cherasse, Toshie Naoi, Yuki Sugaya, Takeshi Sakurai, Masanobu Kano, Masanori Sakaguchi. CaliAli, a tool for long-term tracking of neuronal population dynamics in calcium imaging. bioRxiv. 2023
Iyo Koyanagi, Taro Tezuka, Jiahui Yu, Sakthivel Srinivasan, Toshie Naoi, Shinnosuke Yasugaki, Ayaka Nakai, Shimpei Taniguchi, Yu Hayashi, Yasushi Nakano, et al. Fully automatic REM sleep stage-specific intervention systems using single EEG in mice. Neuroscience research. 2022. 186. 51-58
Tezuka T, Kumar D, Singh S, Koyanagi I, Naoi T, Sakaguchi M. Real-time, automatic, open-source sleep stage classification system using single EEG for mice. Scientific Reports. 2021. 11. 1. 11151-11151
Luana C Soares, Osama Al-Dalahmah, James Hillis, Christopher C Young, Isaiah Asbed, Masanori Sakaguchi, Eric O'Neill, Francis G Szele. Novel Galectin-3 Roles in Neurogenesis, Inflammation and Neurological Diseases. Cells. 2021. 10. 11
Masaki Taniguchi, Taro Tezuka, Pablo Vergara, Sakthivel Srinivasan, Takuma Hosokawa, Yoan Cherasse, Toshie Naoi, Takeshi Sakurai, Masanori Sakaguchi. Open-Source Software for Real-time Calcium Imaging and Synchronized Neuron Firing Detection. IEEE EMBC 2021. 2021. 2997-3003

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MISC (14)：

菅谷佑樹, 坂口昌徳. 成体海馬の新生ニューロンが睡眠中に記憶を固定化する. BRAIN and NERVE: 神経研究の進歩. 2021. 73. 7. 0813-0817
石橋哲, 坂口昌徳, 山根淳一, 金村米博, 中村雅也, 澤本和延, 戸山芳昭, 岡野栄之, 水澤英洋. 局所脳虚血モデルに対するガレクチン-1遺伝子導入ヒト神経幹細胞移植効果の検討. 臨床神経学. 2012. 52. 12. 1404-1404
廣田ゆき, MEUNIER Alice, 黄詩惠, 下澤東吾, 山田理, 木田泰之, 井上雅史, 伊東翼, 加藤寛子, 坂口昌徳, et al. 非筋細胞ミオシンIIによるマウス上衣細胞繊毛の平面極性制御. Nagoya Med J. 2011. 51. 4. 219
Yoichi Imaizumi, Masanori Sakaguchi, Tsuyoshi Morishita, Mamoru Ito, Francoise Poirier, Kazunobu Sawamoto, Hideyuki Okano. Galectin-1 is expressed in early type neural progenitor cells and down-regulates neurogenesis in the adult hippocampus. NEUROSCIENCE RESEARCH. 2010. 68. E365-E365
Makiko Ikeda, Yuki Hirota, Masanori Sakaguchi, Osamu Yamada, Yasuyuki Kida, Tashihiko Ogura, Takanobu Otsuka, Hideyuki Okano, Kazunobu Sawamoto. Role of Diversin as a possible switch of distinct Wnt pathways regulating multiple steps of adult neurogenesis. NEUROSCIENCE RESEARCH. 2009. 65. S54-S54

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Patents (6)：

判定装置、光照射装置、及びプログラム
小型撮像装置
Agent for inhibiting proliferation of neural stem cells.
Methods for enhancing survival and/or proliferation of neural stem cells and neurite extension enhancers therefore pharmaceutical compositions containing neural stem cells assay methods and screening methods.
Method of promoting subsistence and/or proliferation of neural stem cell and promoting extension of neurite, promoter therefor, pharmaceutical composition containing neural stem cell, method of assay and method of screening

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Books (11)：

睡眠学第2版
朝倉書店 2019
トラウマ記憶を弱めるには ? マウスの記憶・睡眠研究から考えるPTSDケア
AdademistJournal 2017
トラウマ直後の環境条件の記憶汎化における重要性-心的外傷後ストレス障害(PTSD)治療における意義
医歯薬出版(株) 2016
脳内で新生するニューロンと、中枢神経再生への応用
クバプロ 2016 ISBN:9784878051456
Recombinant sugar binding proteins and their functional analysis: Galectin-1
JCGGDB 2014

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Lectures and oral presentations (58)：

Hippocampal Adult-Born Neurons for Memory Consolidation during REM Sleep
(U of T Brain and Bee seminar 2022)
CaliAli (Calcium imaging inter-session alignment): neuronal tracing utilizing vasculature in calcium imaging
(Frankland lab seminar 2022)
Fully automatic sleep stage-specific intervention using single EEG in mice
(Frankland lab seminar 2022)
Transient recruitment of adult-born neurons for fear memory consolidation in REM sleep
(2022)
CaliAli (Calcium imaging inter-session alignment): neuronal tracing utilizing vasculature in calcium imaging
(2022)

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Education (2)：

2001 - 2005 Tsukuba University Conprehensive Human Sciences Medicine Doctural Course
1995 - 2001 Tsukuba University School of Medicine Department of Medicine

Professional career (1)：

Work history (12)：

2022/04 - 現在 University of Tsukuba Faculty of Medicine Assc Prof (Tenure)
2021/10 - 現在 National Center of Neurology and Psychiatry
2018/10 - 現在 Tsukuba University International Institute for Integrative Sleep Medicine Associate Professor, PI
2013/04 - 2018/09 Tsukuba University International Institute for Integrative Sleep Medicine Associate Professor, co-PI
2013/02 - 2013/03 Univ. Tsukuba WPI-IIIS Researcher

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Awards (9)：

2022/10 - 筑波大学優秀教員表彰
2021/01 - 2021 Inscopix Tech Award SFN Global connectome
2016 - Society for Neuroscience Neuroscience?2016 HotTopic The role of adult born neurons in memory consolidation during sleep-wake cycles
2015 - The Adult Neurogenesis Conference 優秀発表賞
2014 - Homeodynamics in Clocks, Sleep and Metabolism Tokyo Translational Therapeutics Meeting 優秀発表賞 The role of adult born neurons during sleep

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