Rchr
J-GLOBAL ID:201201035873444373   Update date: Feb. 01, 2024

Kitajima Shunsuke

キタジマ シユンスケ | Kitajima Shunsuke
Affiliation and department:
Homepage URL  (1): http://kaken.nii.ac.jp/d/r/90566465.ja.html
Research field  (1): Tumor biology
Research keywords  (2): STING-TBK1経路 ,  KRAS変異型肺がん
Research theme for competitive and other funds  (6):
  • 2020 - 2023 KRAS/LKB1変異型肺がんが示す免疫チェックポイント阻害薬治療耐性の克服
  • 2020 - 2022 Identification of STING agonist transporter in cancer cells by utilizing a lineage barcoding system
  • 2014 - 2017 Regulation of metabolism by RB tumor suppressor gene
  • 2014 - 2016 Inflammatory circuit that triggres malignant progression
  • 2013 - 2015 CCL2 induced by RB inactivation contributes to the formation of tumor-promoting inflammatory microenvironment
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Papers (37):
  • 谷 哲夫, 北嶋 俊輔, 吉田 遼平, Barbie David. 稀少ドライバー変異 KRAS変異陽性肺癌でのSTING経路活性化を介した新規治療法の検討. 日本呼吸器学会誌. 2023. 12. 増刊. 191-191
  • Christopher Noyes, Shunsuke Kitajima, Fengkai Li, Yusuke Suita, Saradha Miriyala, Shakson Isaac, Nagib Ahsan, Erik Knelson, Amir Vajdi, Tetsuo Tani, et al. The germline factor DDX4 contributes to the chemoresistance of small cell lung cancer cells. Communications Biology. 2023. 6. 1
  • Shunsuke Kitajima, Tetsuo Tani, Benjamin F Springer, Marco Campisi, Tatsuya Osaki, Koji Haratani, Minyue Chen, Erik H Knelson, Navin R Mahadevan, Jessica Ritter, et al. MPS1 inhibition primes immunogenicity of KRAS-LKB1 mutant lung cancer. Cancer cell. 2022. 40. 10. 1128-1144
  • Ryohei Yoshida, Maria Saigi, Tetsuo Tani, Benjamin F Springer, Hirofumi Shibata, Shunsuke Kitajima, Navin R Mahadevan, Marco Campisi, William Kim, Yoshihisa Kobayashi, et al. MET-induced CD73 restrains STING-mediated immunogenicity of EGFR-mutant lung cancer. Cancer research. 2022. 82. 21. 4079-4092
  • Jindan Sheng, Susumu Kohno, Nobuhiro Okada, Nobuyuki Okahashi, Kana Teranishi, Fumio Matsuda, Hiroshi Shimizu, Paing Linn, Naoko Nagatani, Minako Yamamura, et al. Treatment of Retinoblastoma 1-Intact Hepatocellular Carcinoma With Cyclin-Dependent Kinase 4/6 Inhibitor Combination Therapy. Hepatology (Baltimore, Md.). 2021. 74. 4. 1971-1993
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MISC (22):
  • D Thumkeo, Y Katsura, Y Nishimura, P Kanchanawong, K Tohyama, T Ishizaki, S Kitajima, C Takahashi, T Hirata, N Watanabe, et al. mDia1/3-dependent actin polymerization spatiotemporally controls LAT phosphorylation by Zap70 at the immune synapse. Science advances. 2020. 6. 1. eaay2432
  • Fengkai Li, Shunsuke Kitajima, Naofumi Mukaida, Chiaki Takahashi. Rb inactivation enhances tumor progression by elevating CCL2 expression. CYTOKINE. 2017. 100. 189-190
  • Shunsuke Kitajima, Chiaki Takahashi. Intersection of retinoblastoma tumor suppressor function, stem cells, metabolism, and inflammation. CANCER SCIENCE. 2017. 108. 9. 1726-1731
  • 河野晋, 村中勇人, 北嶋俊輔, 佐々木信成, 鈴木美砂, 髙橋智聡. RBとがんの代謝. 実験医学(増刊号). 2017. 35. 10. 21-25
  • Shunsuke Kitajima, Hajime Asahina, Jillian D. Cavanaugh, Ting Chen, Ashley A. Merlino, Thai C. Tran, Kwonk-Kin Wong, David A. Barbie. Epigenetic activation of IGF1R signaling promotes resistance to momelotinib and MEK inhibition in KRAS-driven lung cancer. CANCER RESEARCH. 2016. 76
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Education (1):
  • 2004 - 2010 Kyoto University
Work history (4):
  • 2020/01 - 現在 Japanese Foundation for Cancer Research
  • 2015/01 - 2020/01 ダナファーバー癌研究所 博士研究員
  • 2013/04 - 2014/12 Kanazawa University Cancer Research Institute
  • 2010/04 - Kanazawa University Cancer Research Institute
Association Membership(s) (2):
THE MOLECULAR BIOLOGY SOCIETY OF JAPAN ,  THE JAPANESE CANCER ASSOCIATION
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