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J-GLOBAL ID：201201040606370615   Update date: Oct. 16, 2024

Sakaba Takeshi

Sakaba Takeshi
Affiliation and department：
Doshisha University Graduate School of Brain Science

About Doshisha University Graduate School of Brain Science


Research field  (2)： Neuroscience - general ,  Basic brain sciences
Research keywords  (2)： 脳・神経 ,  神経科学
Research theme for competitive and other funds  (12)：
  • 2024 - 2028 集団としての皮質シナプス機能を理解、操作するためのアプローチ構築
  • 2024 - 2027 伝達物質放出部位ダイナミクスを軸としたシナプス可塑性の統一的理解
  • 2020 - 2025 Nanoscale visualization and mechanstic understanding of presynaptic plasticity
  • 2021 - 2024 Regulation of hippocampal mossy fiber synapses and its functional significance.
  • 2019 - 2021 海馬苔状線維シナプス・局所神経回路のスクラップ&ビルド
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Papers (54)：
  • Takafumi Miki, Yuji Okamoto, Miyuki Ueno-Umegai, Rio Toyofuku, Shun Hattori, Takeshi Sakaba. Single-vesicle imaging reveals actin-dependent spatial restriction of vesicles at the active zone, essential for sustained transmission. Proceedings of the National Academy of Sciences. 2024. 121. 43. e2402152121
  • Taichi Onishi, Kenzo Hirose, Takeshi Sakaba. Molecular tools to capture active neural circuits. Frontiers in Neural Circuits. 2024. 18
  • Rinako Miyano, Hirokazu Sakamoto, Kenzo Hirose, Takeshi Sakaba. RIM-BP2 regulates Ca2+ channel abundance and neurotransmitter release at hippocampal mossy fiber terminals. eLife. 2024. 12. RP90799
  • Ryota Fukaya, Rinako Miyano, Himawari Hirai, Takeshi Sakaba. Mechanistic insights into cAMP-mediated presynaptic potentiation at hippocampal mossy fiber synapses. Frontiers in Cellular Neuroscience. 2023. 17
  • Ryota Fukaya, Himawari Hirai, Hirokazu Sakamoto, Yuki Hashimotodani, Kenzo Hirose, Takeshi Sakaba. Increased vesicle fusion competence underlies long-term potentiation at hippocampal mossy fiber synapses. Science Advances. 2023. 9. 8. eadd3616
ｍore...
Books (5)：
  • 顆粒放出機構(特集 シナプス)
    生体の科学 2023
  • Synaptic vesicle dynamics at the calyx of Held and other central synapses
    2022
  • 中枢神経系におけるシナプス伝達の生理学(ブレインサイエンス・レビュー2018)
    ブレインサイエンス振興財団 2018
  • スタンフォード神経生物学 Liqun Luo著
    メディカルインターナショナル 2017
  • Patch clamp techinques
    Springer 2012
Lectures and oral presentations  (17)：
  • Kinetic analysis of transmitter release at hippocampal mossy fiber synapses
    (FENS Satellite Symposium, Recent Advancements: Unraveling Synaptic Transmission In Hippocampal Mossy Fiber Synapses, ISTA, Austria 2024)
  • Electrophysiology of synaptic transmission (in Japanese)
    (The 46th meeting of the Japanese Neuroscience Society 2023)
  • Synaptic vesicle pools at mammalian central synapses
    (2021 Annual meeting of Korea Society for Brain and Neural Sciences (KSBNS) 2021)
  • Kinetics of transmitter release at hippocampal mossy fiber synapses
    (Kinetics of transmitter release at hippocampal mossy fiber synapses 2019)
  • Comparison of the transmitter release properties between the calyx of Held synapse and mossy fiber-CA3 synapse
    (Quantitaive aspects of membrane fuison and fission, Biopysical Society Thematic meetings 2019)
ｍore...
Work history (1)：
  • 2011 - 現在 Doshisha University
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