Tanaka Toshihiro

タナカトシヒロ | Tanaka Toshihiro

Affiliation and department：
Homepage URL (1)： http://www.tmd.ac.jp/grad/hgdd/

Research field (1)： Cardiology

Research theme for competitive and other funds (13)：

2022 - 2025 歯の異常に多様性をもたらす分子機構の解明へ向けた組織特異的横断的オミクス解析
2022 - 2025 侵襲性歯周炎の原因遺伝子NOD2変異型の機能解析
2019 - 2023 Elucidation of etiology of facial asymmetry based on integrated genome-phenome analysis
2019 - 2022 病的近視による眼球変形メカニズム解明と眼球壁再生治療の確立
2019 - 2022 統合的オミックス解析による希少遺伝性疾患における歯数を規定する分子機構の解明

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Papers (216)：

Yuki Nagata, Ryo Watanabe, Christian Eichhorn, Seiko Ohno, Takeshi Aiba, Taisuke Ishikawa, Yukiko Nakano, Yoshiyasu Aizawa, Kenshi Hayashi, Nobuyuki Murakoshi, et al. Targeted deep sequencing analyses of long QT syndrome in a Japanese population. PloS one. 2022. 17. 12. e0277242
Todd A Johnson, Yoichi Mashimo, Jer-Yuarn Wu, Dankyu Yoon, Akira Hata, Michiaki Kubo, Atsushi Takahashi, Tatsuhiko Tsunoda, Kouichi Ozaki, Toshihiro Tanaka, et al. Association of an IGHV3-66 gene variant with Kawasaki disease. Journal of human genetics. 2021. 66. 5. 475-489
Yumi Inagaki, Takuya Ogawa, Makoto J Tabata, Yuki Nagata, Ryo Watanabe, Tatsuo Kawamoto, Keiji Moriyama, Toshihiro Tanaka. Identification of OPN3 as associated with non-syndromic oligodontia in a Japanese population. Journal of human genetics. 2021. 66. 8. 769-775
Kazuyoshi Ishigaki, Masato Akiyama, Masahiro Kanai, Atsushi Takahashi, Eiryo Kawakami, Hiroki Sugishita, Saori Sakaue, Nana Matoba, Siew-Kee Low, Yukinori Okada, et al. Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases. Nature genetics. 2020. 52. 7. 669-679
Yoshiki Higashijima, Yusuke Matsui, Teppei Shimamura, Ryo Nakaki, Nao Nagai, Shuichi Tsutsumi, Yohei Abe, Verena M Link, Mizuko Osaka, Masayuki Yoshida, et al. Coordinated demethylation of H3K9 and H3K27 is required for rapid inflammatory responses of endothelial cells. The EMBO journal. 2020. 39. 7. e103949

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MISC (140)：

Keiko Shimamoto, Takeshi Aiba, Tsukasa Kamakura, Mitsuru Wada, Kenichiro Yamagata, Koji Miyamoto, Kohei Ishibashi, Yuko Inoue, Koji Miyamoto, Satoshi Nagase, et al. Clinical Features and Long-Term Prognosis of Patients With Phenotype-Positive but Genotype-Negative Long-QT Syndrome. CIRCULATION. 2019. 140
清水渉, 山形研一郎, 野田崇, 草野研吾, 宮崎文, 牧山武, 伊藤英樹, 大野聖子, 渡部裕, 林研至, et al. 先天性QT延長症候群の遺伝的および臨床的特徴日本の多施設共同レジストリの結果(Genetics and Clinical Aspects of Congenital Long-QT Syndrome: Results from the Japanese Multicenter Registry). 日本循環器学会学術集会抄録集. 2019. 83回. LBCS2-2
清水渉, 山形研一郎, 野田崇, 草野研吾, 宮崎文, 牧山武, 伊藤英樹, 大野聖子, 渡部裕, 林研至, et al. Genetics and Clinical Aspects of Congenital Long-QT Syndrome: Results from the Japanese Multicenter Registry(和訳中). 日本循環器学会学術集会抄録集. 2019. 83回. LBCS2-2
須藤毅顕, 小林宏明, 青木章, 田中敏博. 全エクソーム解析による疾患遺伝子の同定-侵襲性歯周炎のNOD2遺伝子の変異の同定-. 最新醫學. 2019. 74. 2. 207-214
須藤毅顕, 岡田随象, 尾崎浩一, 浦山ケビン, 金井仁弘, 小林宏明, 御給美沙, 和泉雄一, 田中敏博. 侵襲性歯周炎における遺伝子変異の同定. 歯界展望. 2018. 132. 6. 1101-1104

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Patents (40)：

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Education (2)：

1992 - 1996 University of Tokyo Graduate School of Medicine
1986 - 1990 University of Tokyo Faculty of Medicine

Professional career (1)：

博士(医学) (東京大学大学院)

Work history (13)：

2013/04 - 現在 Tokyo Medical and Dental University Graduate School of Medical and Dental Sciences Professor
2013/04 - 2016/03 RIKEN Center for Integrative Medical Sciences Group Director
2013/04 - 2015/03 RIKEN Center for Integrative Medical Sciences Deputy Director
2009/04 - 2013/03 Center for Genomic Medicine, RIKEN Deputy Director
2008/04 - 2013/03 Center for Genomic Medicine, RIKEN Group Director

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Awards (2)：

2005 - The Commendation for Science and Technology by the Minister of Education, Culture, Sports, Science and Technology The Young Scientists’ Prize
2004 - Japanese Society for Human Genetics Encouragement Award

Association Membership(s) (5)：

American Heart Association , American Society of Human Genetics , THE JAPAN SOCIETY OF HUMAN GENETICS , JAPANESE COLLEGE OF CARDIOLOGY , JAPANESE CIRCULATION SOCIETY

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