Research field (1)：
Environmental and pharmaceutical development resources
Research keywords (4)：
伝統医学
, 放線菌
, 生合成
, 天然物化学
Research theme for competitive and other funds (6)：
2020 - 2023 Verification of Southeast Asian traditional medicine
2017 - 2020 Evidence of medicinal properties and efficacy of Southeast Asian medicinal plants
2015 - 2019 Collection of new natural sources and analysis of their chemical constituents and construction of genetic resource bank
2014 - 2017 Biosynthetic studies on actinomycete metabolites for development of novel diabetes drugs
2012 - 2014 Biosynthetic study of manumycin antibiotics for creating novel analogs
2006 - 2009 Distribution Research of Malagasy and Kenyan medicinal plants and Development of Medical and Pharmaceutical Sources
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Papers (93)：
Takuro Kobori, Yui Ito, Yoko Urashima, Takuya Ito, Nobumasa Takagaki, Kikuko Hotta, Tokio Obata. Ezrin works as a scaffold protein for a macrophage checkpoint molecule CD47, leading to a poor prognosis for patients with uterine cervical squamous cell carcinoma. Taiwanese journal of obstetrics & gynecology. 2025. 64. 2. 239-247
Takuro Kobori, Mikiko Sugimoto, Takuya Ito, Kikuko Hotta. Involvement of Intracellular Scaffold Proteins in the Expression of Immune Checkpoint Molecule PD-L1 and Prognosis in Patients with Glioblastoma. Journal of AYA Oncology Alliance. 2024. 4. 2. 35-45
Senda Kartika Rakainsa, Khoirun Nisa, Takuya Ito, Hiroyuki Morita. Antibacterial activity of five Indonesian medicinal plants and the isolation of compounds from Plectranthus scutellarioides. Journal of Applied Pharmaceutical Science. 2024. 14. 5. 185-192
小堀宅郎, 伊藤優衣, 浦嶋庸子, 伊藤卓也, 堀田紀久子, 小畑友紀雄. Role of ERM proteins in the plasma membrane expression of PD-L1 in the ovarian clear cell adenocarcinoma common in Japanese women. 日本薬学会年会要旨集(Web). 2024. 144th
伊藤優衣, 小堀宅郎, 浦嶋庸子, 伊藤卓也, 堀田紀久子, 小畑友紀雄. Moesin affects the expression and functionality of an innate immune checkpoint molecule CD47 in human ovarian clear cell adenocarcinoma. 日本薬学会年会要旨集(Web). 2024. 144th
澤田優果, 伊藤優衣, 小堀宅郎, 浦嶋庸子, 伊藤卓也, 高垣伸匡, 小畑友紀雄. Ezrin modulates the cellular membrane localization of the macrophage checkpoint molecule CD47 in human uterine cervical squamous cell carcinoma. 日本薬学会年会要旨集(Web). 2024. 144th
Structural analysis of a novel prenyltransferase
(量子ビームサイエンスフェスタ(Web) 2023)
Crystal structure analysis of novel enzyme derived from Streptomyces.
(KEK Progress Report (Web) 2023)
Involvement of Ezrin/Radixin/Moesin in the cell surface expression of immune checkpoint molecule PD-L1 in human endometrial carcinoma cell line
(日本薬学会年会要旨集(Web) 2023)
Ezrin modulates the cell surface localization of Programmed Death Ligand-1 in HEC-151 cells.
(日本薬学会年会要旨集(Web) 2023)
Ezrin contributes to the plasma membrane expression of Programmed Death Ligand-1 in A2780 cells
(日本薬学会年会要旨集(Web) 2023)
