Okazaki Toshiro

オカザキトシロウ | Okazaki Toshiro

Affiliation and department：
Job title：客員教授

Research field (1)： Hematology and oncology

Research theme for competitive and other funds (18)：

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Papers (156)：

Makoto Taniguchi, Shingo Nagaya, Kohei Yuyama, Ai Kotani, Yasuyuki Igarashi, Toshiro Okazaki. Ceramide Metabolism Regulated by Sphingomyelin Synthase 2 Is Associated with Acquisition of Chemoresistance via Exosomes in Human Leukemia Cells. International journal of molecular sciences. 2022. 23. 18
Jun Fujita, Makoto Taniguchi, Chieko Hashizume, Yoshibumi Ueda, Shota Sakai, Tadakazu Kondo, Mayumi Hashimoto-Nishimura, Kentaro Hanada, Takeo Kosaka, Toshiro Okazaki. Nuclear Ceramide Is Associated with Ataxia Telangiectasia Mutated Activation in the Neocarzinostatin-Induced Apoptosis of Lymphoblastoid Cells. Molecular Pharmacology. 2022. 101. 5. 322-333
Makoto Taniguchi, Toshiro Okazaki. Role of ceramide/sphingomyelin (SM) balance regulated through "SM cycle" in cancer. Cellular signalling. 2021. 87. 110119-110119
Takenaga Hiranuma, Ken Watanabe, Tadashi Yamashita, Toshiro Okazaki, Yoshihiro Tokudome. Role of collagen degradation pathway in sphingomyelin synthase 2-deficient mouse skin. Biomedical Dermatology. 2021. 5. 1
Yoritaka Fujii, Makoto Taniguchi, Shingo Nagaya, Yoshibumi Ueda, Chieko Hashizume, Ken Watanabe, Hiroyuki Takeya, Takeo Kosaka, Toshiro Okazaki. A novel mechanism of thrombocytopenia by PS exposure through TMEM16F in sphingomyelin synthase 1 deficiency. Blood advances. 2021. 5. 20. 4265-4277

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MISC (62)：

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Books (6)：

総論編5 セラミド関連脂質シグナリング ~セラミドの多様な生理活性~
食品化学新聞社 2019 ISBN:9784916143358
各論応用35 医療分野への応用がんとセラミド関連物質
食品化学新聞社 2019
第8節スフィンゴミエリン合成酵素・スフィンゴミエリナーゼ
2015 ISBN:9784900487550
Role of sphingolipids in hematological malignancies: Lymphoproliferative disorders
2015 ISBN:9783319207490
Unraveling the specific role of sphingomyelins in cell physiology: Where are we?
2015 ISBN:9781634837088

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Lectures and oral presentations (154)：

スフィンゴミエリン合成酵素・欠損は高脂肪食による大腸炎を抑制する
(第12回セラミド研究会学術集会 2019)
Sphingomyelin synthase 2 deficiency inhibits the induction of murine colitis-associated colon cancer,
(1st Japan-Europe workshop on glycolipids and membrane homeostasis, Strasbourg, France 2019)
ROLE OF GLYCOSPHINGOLIPID BALANCE REGULATED BY SPHINGOMYELIN SYNTHASE 2 IN INFLAMMATION AND PROGRESSION OF CANCER IN MURINE MODELS
(25th International symposium on glycoconjugates, Milano, Italy August 25-31, 2019 2019)
高脂肪食およびDSSによる大腸炎に対するスフィンゴエミリン合成酵素2ノックアウトの影響
(第74回日本消化器外科学会総会 2019)
Deficiency of sphingomyelin synthase 2 prolongs survival by inhibition of lymphoma infiltration through ICAM-1 reduction.
(14the Sphingotherapy Conference, Kaga, Ishikawam Japan. 2019)

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Education (1)：

Professional career (1)：

Work history (13)：

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Awards (1)：

Association Membership(s) (7)：

日本内科学会 , 日本生化学会 , 日本自動化学会 , 日本脂質生化学会 , 日本検査医学会 , 日本血液学会 , 日本癌治療学会

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