Rchr
J-GLOBAL ID：201201069027149212   Update date: Oct. 21, 2024

Yamamoto Tohru

ヤマモト トオル | Yamamoto Tohru
Affiliation and department：
Kagawa University Faculty of Medicine School of Medicine

About Kagawa University Faculty of Medicine School of Medicine


Homepage URL  (1)： http://www.med.kagawa-u.ac.jp/faculty/center/igaku_kouza/bunshi_shinkei/
Research field  (6)： Pharmacology ,  Neuroscience - general ,  Cell biology ,  Pharmaceuticals - health and biochemistry ,  Neuroanatomy and physiology ,  Molecular biology
Research keywords  (17)： 統合失調症 ,  Autistic Spectrum Disorder ,  小胞輸送 ,  軸索輸送 ,  シナプス形成 ,  神経発生 ,  アルツハイマー病 ,  神経回路 ,  神経分化 ,  運動神経 ,  軸索ガイダンス ,  大脳皮質 ,  軸索伸長 ,  ニワトリ ,  電気穿孔法 ,  脊髄神経 ,  脊髄
Research theme for competitive and other funds  (23)：
  • 2022 - 2025 Functional Analyses of 'privileged' vesicular transport carried with Alcadein
  • 2019 - 2022 神経回路の新しい興奮性/抑制性バランス制御機構に着目した精神神経疾患治療薬の探索
  • 2016 - 2020 Functional analysis of MDGA family proteins on regulation of synapse formation and social behavior.
  • 2013 - 2016 Functional analysis of MDGA family proteins on neural circuit formation of cerebral cortex.
  • 2010 - 2012 Functional analysis of MDGA family proteins on corticogenesis.
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Papers (68)：
  • Daiki Ojima, Yoko Tominaga, Takashi Kubota, Atsushi Tada, Hiroo Takahashi, Yasushi Kishimoto, Takashi Tominaga, Tohru Yamamoto. Impaired Hippocampal Long-Term Potentiation and Memory Deficits upon Haploinsufficiency of MDGA1 Can Be Rescued by Acute Administration of d-Cycloserine. International Journal of Molecular Sciences. 2024
  • Keiko Honda, Hiroo Takahashi, Saori Hata, Ruriko Abe, Takashi Saito, Takaomi C Saido, Hidenori Taru, Yuriko Sobu, Kanae Ando, Tohru Yamamoto, et al. Suppression of the amyloidogenic metabolism of APP and the accumulation of Aβ by alcadein α in the brain during aging. Scientific Reports. 2024. 14. 1. 18471-18471
  • Yuzuha Shiraki, Monet Mitsuma, Ritsuko Takada, Saori Hata, Akira Kitamura, Shinji Takada, Masataka Kinjo, Hidenori Taru, Ulrike C Müller, Tohru Yamamoto, et al. Axonal transport of Frizzled5 by Alcadein α-containing vesicles is associated with kinesin-1. Molecular Biology of the Cell. 2023. 34. 11. ar110
  • Emre Fertan, Aimée A Wong, Thalia S Garvock-de Montbrun, Michaela K Purdon, Kyle M Roddick, Tohru Yamamoto, Richard E Brown. Early postnatal development of the MDGA2+/- mouse model of synaptic dysfunction. Behavioural Brain Research. 2023. 452. 114590-114590
  • Saori Hata, Haruka Saito, Takeharu Kakiuchi, Dai Fukumoto, Shigeyuki Yamamoto, Kensaku Kasuga, Ayano Kimura, Koichi Moteki, Ruriko Abe, Shungo Adachi, et al. Brain p3-Alcβ peptide restores neuronal viability impaired by Alzheimer's amyloid β-peptide. EMBO Molecular Medicine. 2023. 15. 5. e17052
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MISC (8)：
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Education (2)：
  • - 1992 The University of Tokyo Graduate School of Pharmaceutical Sciences Department of Pharmaceutical Technology
  • - 1987 The University of Tokyo Faculty of Pharmaceutical Sciences Department of Pharmacy
Professional career (1)：
  • Ph.D. (The University of Tokyo)
Work history (9)：
  • 2013/08 - 現在 Kagawa University School of Medicine, Faculty of Medicine
  • 2006/04 - 2013/07 北海道大学 薬学研究院 准教授
  • 2003/05 - 2006/03 理化学研究所 発生・再生科学総合研究センター 研究員
  • 2000/06 - 2003/04 Tohoku University Institute of Development, Aging and Cancer
  • 1999/04 - 2000/05 Columbia University
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Awards (1)：
  • 井上科学振興財団 井上研究奨励賞
Association Membership(s) (5)：
THE MOLECULAR BIOLOGY SOCIETY OF JAPAN ,  THE JAPANESE BIOCHEMICAL SOCIETY ,  THE PHARMACEUTICAL SOCIETY OF JAPAN ,  THE JAPANESE ASSOCIATION OF ANATOMISTS ,  THE JAPAN NEUROSCIENCE SOCIETY
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