Umehara Takahiro

ウメハラタカヒロ | Umehara Takahiro

Affiliation and department：

Research field (2)： Plastic and reconstructive surgery , Forensic medicine

Research keywords (4)：創傷治癒 , 糖尿病 , 低体温 , 熱産生

Research theme for competitive and other funds (17)：

2021 - 2025 好中球と関連miRNA発現制御による創傷治癒遅延機構の解明と革新的治療法の開発
2021 - 2024 寒冷応答miRNA発現プロファイルによる凍死診断の革新的アプローチ
2019 - 2022 寒冷応答組織の体系的遺伝子発現プロファイルによる革新的凍死診断法の確立
2018 - 2021 死後組織由来iPS細胞を活用した新たな剖検診断スキーム基盤体制の確立
2018 - 2021 Transcriptomeを応用した法医病理学的損傷受傷時期推定法の開発

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Papers (27)：

Takahiro Umehara, Shinichiro Kagawa, Aiko Tomida, Takehiko Murase, Yuki Abe, Keita Shingu, Kazuya Ikematsu. Body temperature-dependent microRNA expression analysis in rats: rno-miR-374-5p regulates apoptosis in skeletal muscle cells via Mex3B under hypothermia. Scientific Reports. 2020. 10. 1
Takuma Yamamoto, Makoto Otsu, Takashi Okumura, Yumi Horie, Yasuharu Ueno, Hideki Taniguchi, Manami Ohtaka, Mahito Nakanishi, Yuki Abe, Takehiko Murase, et al. Generation of three induced pluripotent stem cell lines from postmortem tissue derived following sudden death of a young patient with STXBP1 mutation. Stem cell research. 2019. 39. 39. 101485-101485
Torbica T, Wicks K, Umehara T, Gungordu L, Alrdahe S, Wemyss K, Grainger JR, Mace KA. Chronic inflammation in response to injury: retention of myeloid cells in injured tissue is driven by myeloid cell-intrinsic factors. J Invest Dermatol. 2019. 139. 7. 1583-1592
Takahiro Umehara, Ryoichi Mori, Kimberly A Mace, Takehiko Murase, Yuki Abe, Takuma Yamamoto, Kazuya Ikematsu. Identification of Specific miRNAs in Neutrophils of Type 2 Diabetic Mice: Overexpression of miRNA-129-2-3p Accelerates Diabetic Wound Healing. Diabetes. 2019. 68. 3. 617-630
Takahiro Umehara, Takehiko Murase, Yuki Abe, Hiromi Yamashita, Yoshinori Shibaike, Shinichiro Kagawa, Takuma Yamamoto, Kazuya Ikematsu. Identification of potential markers of fatal hypothermia by a body temperature-dependent gene expression assay. International journal of legal medicine. 2019. 133. 2. 335-345

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MISC (23)：

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Lectures and oral presentations (29)：

2型糖尿病由来好中球の炎症制御に関与するmicroRNAの同定及び機能解析
(第50回日本創傷治癒学会 2020)
ラット腸腰筋における体温依存的microRNA発現動態:低体温下におけるmiR-374-5pの機能解析
(第70回日本法医学会学術九州地方集会 2020)
体温低下に伴う腸腰筋の分子動態解析及び凍死診断に有用な分子マーカーの同定
(第104次日本法医学会学術全国集会 2020)
Identification of specific circular RNAs in diabetic-derived neutrophils
(2019)
凍死診断に有用な腸腰筋特異的microRNAの同定及び機能解析
(第69回日本法医学会学術九州地方集会 2019)

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Professional career (1)：

博士(医学) (九州大学)

Work history (3)：

2014/06 - 現在 Nagasaki University Graduate School of Biomedical Sciences Assistant Professor
2013/06 - 2014/05 Manchester University Healing Foundation Centre Visiting Scientist
2011/05 - 2013/05 Nagasaki University Graduate School of Biomedical Sciences Assistant Professor

Awards (1)：

2020/11 - The Japanese Society for Wound Healing 第50回研究奨励賞

Association Membership(s) (3)：

The Molecular Biology Society of Japan , JAPANESE SOCIETY OF LEGAL MEDICINE , The Japanese Society for Wound Healing

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