Yagishita Sosuke

Affiliation and department：

Research field (1)： Neuroscience - general

Research theme for competitive and other funds (7)：

2023 - 2026 Analyses of the relationship between neuronal activity-dependent protein synthesis and neurofibrillary tangles formation
2019 - 2022 The mechanisms of neurofibrillary tangle formation during ageing and the progression of Alzheimer disease
2016 - 2019 Mechanisms of memory impairment caused by the increase in phosphorylated tau
2014 - 2018 A novel therapeutic strategy for Alzheimer's disease based on the promotion of clearance mechanism of amyloid beta protein
2013 - 2017 Readjustment of "amyloid hypothesis" for developing methods to treat Alzheimer disease

Show all

Papers (19)：

Takeru Nagayama, Sosuke Yagishita, Megumi Shibata, Akiko Furuno, Takashi Saito, Takaomi C. Saido, Shuji Wakatsuki, Toshiyuki Araki. Transient sleep apnea results in long-lasting increase in β-amyloid generation and tau hyperphosphorylation. Neuroscience Research. 2024
Kensuke Iwasa, Sosuke Yagishita, Nan Yagishita-Kyo, Anzu Yamagishi, Shinji Yamamoto, Kota Yamashina, Chikara Haruta, Masashi Asai, Kei Maruyama, Kuniyoshi Shimizu, et al. Long term administration of loquat leaves and their major component, ursolic acid, attenuated endogenous amyloid-β burden and memory impairment. Scientific Reports. 2023. 13. 1
Nan Yagishita-Kyo, Yuki Ikai, Tomoko Uekita, Akio Shinohara, Chihiro Koshimoto, Keisuke Yoshikawa, Kei Maruyama, Sosuke Yagishita. Testosterone interrupts binding of Neurexin and Neuroligin that are expressed in a highly socialized rodent, Octodon degus. Biochemical and Biophysical Research Communications. 2021. 551. 54-62
Sosuke Yagishita, Akira Hirasawa. Intermittent hypoxia produces Alzheimer disease?. ONCOTARGET. 2017. 8. 26. 41786-41787
Kensuke Iwasa, Shinji Yamamoto, Sosuke Yagishita, Kei Maruyama, Keisuke Yoshikawa. Excitotoxicity-induced prostaglandin D-2 production induces sustained microglial activation and delayed neuronal death. JOURNAL OF LIPID RESEARCH. 2017. 58. 4. 649-655

ｍore...

MISC (7)：

栁下聡介. 閉塞性睡眠時無呼吸と認知機能低下. THE LUNG perspectives. 2020. 28. 1
栁下聡介. 閉塞性睡眠時無呼吸とアルツハイマー病との関係. オベリスク. 2020. 25. 1
米村洋而, 二井勇人, 柳下聡介, 周防諭, 富田泰輔, 岩坪威, 石浦章一. 酵母再構成系によるγ-セクレターゼにおけるPS1とPS2の比較. 日本分子生物学会年会プログラム・要旨集(Web). 2011. 34th
Masashi Asai, Sosuke Yagishita, Nobuhisa Iwata, Takaomi Saido, Shoichi Ishiura, Kei Maruyama. The metabolism of APP C-terminal fragments by y-secretase and cathepsin B. JOURNAL OF PHARMACOLOGICAL SCIENCES. 2010. 112. 136P-136P
Sosuke Yagishita, Masashi Asai, Nobuhisa Iwata, Takaomi Saido, Kei Maruyama, Shoichi Ishiura. Cathepsin 8 inhibitor CA-074Me causes the accumulation of APP C-terminal fragments independently of secretases activities. NEUROSCIENCE RESEARCH. 2009. 65. S64-S64

ｍore...

Books (2)：

Chapter 7:Co-immunoprecipitation Assay to Investigate the Interaction Strength Between Synaptic Proteins Using COS-7 Cells
2018
神経変性疾患では細胞内外に異常蛋白質が蓄積する
2018

Lectures and oral presentations (43)：

バンコマイシン投与による腸内細菌叢の攪乱は,脳内の Aβ量を増加させる
(第42回日本認知症学会学術集会 2023)
微小管との結合に影響を与えるタウのリン酸化部位について
(タウ研究会2023 2023)
The mechanisms of formation of social novelty by gut microbiota.
(9th Congress for International Human Microbiome Consortium 2022)
Neuronal activity-dependent alteration of tau phosphorylation.
(2022)
神経活動に依存したタウのリン酸化変動
(NEURO2022 2022)

ｍore...

Work history (4)：

Awards (5)：

Association Membership(s) (4)：

Society for Neuroscience , 日本神経科学学会 , 日本生化学会 , 日本認知症学会

※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

Return to Previous Page