Ando Hiromune

アンドウヒロムネ | Ando Hiromune

Affiliation and department：
Other affiliations (3)：

Gifu University
Gifu University The United Graduate School of Agricultural Science
Kyoto University

Homepage URL (1)： http://kaken.nii.ac.jp/ja/r/20372518

Research field (2)： Bioorganic chemistry , Molecular biochemistry

Research keywords (16)：シグレック , 分子プローブ , 免疫 , ガングリオシド , 糖鎖 , 脳・神経 , 感染 , 癌 , 自己免疫疾患 , セレクチン , 複合糖質 , 神経回路網形成 , オリゴシアル酸 , 糖鎖工学 , シアル酸 , 包括脳ネットワーク

Research theme for competitive and other funds (28)：

2022 - 2026 An extedned research of cell membrane domains based on the probes of membrane molecules
2019 - 2022 光触媒による2-デオキシ糖の立体選択的グリコシル化の開発とミスラマイシンの全合成
2018 - 2022 Study for elucidation of the structures and functions of nano-sized membrane domains using glycolipid probes
2019 - 2021 光触媒による2-デオキシ糖の立体選択的グリコシル化の開発とミスラマイシンの全合成
2015 - 2018 Integrative understanding of linkage between molecular structures and functions of glycosphingolipids in signal regulation

2015 - 2018 Verification of unit raft hypothesis by high-resolution single-molecule imaging

2015 - 2018 細胞膜糖鎖ドメインの形成と機能の動的機構の解明

2014 - 2016 神経細胞膜ラフト可視化のためのガングリオシドプローブの開発

2012 - 2015 Unraveling of mechanisms of raft signaling as revealed by single-molecule imaging at high resolution

2014 - 2015 神経細胞膜ラフト可視化のためのガングリオシドプローブの開発

2011 - 2015 ガングリオシドが持つ神経突起促進活性の分子基盤の解明

2012 - 2014 Development of imaging probes of neuronal gangliosides

2011 - 2014 Elucidation of Molecular Basis Underlying Neurogenesis which is Promoted by Gangliosides

2012 - 2014 神経系ガングリオシドのイメージング用プローブの創製

2011 - 2014 ガングリオシドが持つ神経突起促進活性の分子基盤の解明

2012 - 2013 神経系ガングリオシドのイメージング用プローブの創製

2012 - 2012 神経系ガングリオシドのイメージング用プローブの創製

2011 - 2012 ガングリオシドが持つ神経突起促進活性の分子基盤の解明

2009 - 2010 Evaluation of the resistance of selenium-containing glycans to enzymatic hydrolysis

2005 - 2010 人工複合糖質プローブの創製と高次生命機能の制御

2005 - 2009 CREATION OF ARTIFICIAL COMPLEX CARBOHYDRATE PROBES AND MODULATION OF HIGHER BIOLOGICAL FUNCTIONS

2006 - 2007 合成難関糖鎖の新規構築法の確立と応用

2004 - 2006 高分子支援戦略によるポリシアル酸迅速大量合成法の開拓

2004 - 2005 異性体化学分割法によるシアル酸オリゴマーの精密合成

2004 - 2005 高分子支援戦略によるポリシアル酸迅速大量合成法の開拓

2002 - 2004 新規シアロ糖鎖固相合成法の開発と応用

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Papers (99)：

Rita Pal, Ayano Yamazaki, Naoko Komura, Hide Nori Tanaka, Akihiro Imamura, Hideharu Ishida, Hiromune Ando. Convergent synthesis of functionalized derivatives of stage-specific embryonic antigens 3 & 4. Carbohydrate Research. 2024. 535
Rui Hagino, Keita Mozaki, Naoko Komura, Akihiro Imamura, Hideharu Ishida, Hiromune Ando, Hide Nori Tanaka. Synthetic Approaches to Ribosyl Adenosine 5′,5′′-Diphosphate Fragment of Poly(ADP-ribose). European Journal of Organic Chemistry. 2023. 26. 41
Kenichi G. N. Suzuki, Naoko Komura, Hiromune Ando. Recently developed glycosphingolipid probes and their dynamic behavior in cell plasma membranes as revealed by single-molecule imaging. Glycoconjugate Journal. 2023
Tsuyoshi Asano, Taro Udagawa, Naoko Komura, Akihiro Imamura, Hideharu Ishida, Hiromune Ando, Hide-Nori Tanaka. Unprecedented neighboring group participation of C2 N-imidoxy functionalities for 1,2-trans-selective glycosylation. Carbohydrate research. 2023. 527. 108808-108808
Eriko Yamaguchi, Naoko Komura, Hide-Nori Tanaka, Akihiro Imamura, Hideharu Ishida, Sophie Groux-Degroote, Martina Mühlenhoff, Kenichi G N Suzuki, Hiromune Ando. Fluorescent GD2 analog for single-molecule imaging. Glycoconjugate journal. 2023. 40. 2. 247-257

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MISC (88)：

NAKANO Mikito, HANASHIMA Shinya, HARA Toshiaki, KABAYAMA Kazuya, KOMURA Naoko, ANDO Hiromune, NYHOLM Thomas K. M., SLOTTE Peter J., MURATA Michio. Membrane Lipids Affect the Interplay between the Transmembrane Domain of the EGF Receptor and Ganglioside GM3-Thermodynamic Quantification of the Lateral Interaction using FRET. 日本化学会春季年会講演予稿集(Web). 2021. 101st
友田千尋, 矢野陽, 花島慎弥, 河村奈緒子, 安藤弘宗, 村田道雄, LONDON Erwin. FRET analysis for the sphingolipid domains in model bilayer membranes using the fluorescent sphingolipid probes. 日本化学会春季年会講演予稿集(Web). 2021. 101st
NAKANO Mikito, HANASHIMA Shinya, HARA Toshiaki, KABAYAMA Kazuya, FUKASE Koichi, MURATA Michio, ANDO Hiromune, SUZUKI Kenichi G. N., SLOTTE J. Peter. Evaluation of lateral interactions between membrane gangliosides and receptor transmembrane segments in lipid bilayers based on semi-quantitative fluorescence analysis. 日本化学会春季年会講演予稿集(CD-ROM). 2020. 100th
Sachi Asano, Rita Pal, Hide Nori Tanaka, Akihiro Imamura, Hideharu Ishida, Kenichi G.N. Suzuki, Hiromune Ando. Development of fluorescently labeled SSEA-3, SSEA-4, and globo-H glycosphingolipids for elucidating molecular interactions in the cell membrane. International Journal of Molecular Sciences. 2019. 20. 24. 6187-6187
Machi Koikeda, Naoko Komura, Hide Nori Tanaka, Akihiro Imamura, Hideharu Ishida, Makoto Kiso, Hiromune Ando. Synthesis of ganglioside analogs containing fluorescently labeled GalNAc for single-molecule imaging. Journal of Carbohydrate Chemistry. 2019. 38. 7-8. 509-527

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Books (6)：

Sialobiology: Structure, Biosynthesis and Function. Sialic Acid Glycoconjugates in Health and Disease
Bentham Science Publishers 2013
Modern Synthetic Methods in Carbohydrate Chemistry: From Monosaccharides to Complex Glycoconjugates, First Edition
Wiley-VCH Verlag GmbH&Co. KGaA 2013
コールドスプリングハーバー糖鎖生物学第2版
2010
Renewed synthetic approach to gangliosides exploiting versatile and powerful synthetic units, in Methods In Enzymology, Glycomics
2010
シアル酸化学の新局面-過去5年の動向から、「複合糖質の化学と最新応用技術」
2009

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Lectures and oral presentations (85)：

Synthesis and biological evaluation of the mimics of cisligand for CD22.
(7th iCeMS Retreat 2015)
Development of selenium-containing sugar probes for X-ray crystallographic analysis of glycan-protein complexes
(iCeMS International Symposium"Hierarchical Dynamics in Soft Materials and Biological Matter" 2015)
Chemical synthesis of cell surface glycans in pluripotent stem cells for cultivating their biological potential
(iCeMS International Symposium"Hierarchical Dynamics in Soft Materials and Biological Matter" 2015)
Diverse synthesis of gangliosides for exploring functional molecular complexes in the cell membrane
(SFG-JSCR Joint Meeting 2014, Satellite I: Chamical Aspects of Glycobiology 2014)
Synthetic study on fluorescent GPI-anchor for detailing carbohydrate-carbohydrate interaction in lipid raft
(6th iCeMS Retreat 2014)

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Education (3)：

1996 - 1999 Gifu University The United Graduate School of Agricultural Science
1994 - 1996 Gifu University Graduate School of Agriculture
1990 - 1994 Gifu University

Professional career (1)：

博士(農学) (岐阜大学)

Work history (10)：

2021/01 - 現在 Gifu University Institute for Glyco-core Research (iGCORE) Professor
2020/04 - 現在 Tokai National Higher Education and Research System Institute for Glyco-core Research (iGCORE) Professor
2020/04 - 2020/12 Gifu University Center for Highly Advanced Integration of Nano and Life Sciences (G-CHAIN) Professor
2017/04 - 2020/03 Gifu University Center for Highly Advanced Integration of Nano and Life Sciences (G-CHAIN) Professor
2008/03 - 2017/03 Kyoto University Institute for Integrated Cell-Material Science, Kyoto University Associate Professor

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Committee career (1)：

2011 - 現在日本糖質学会評議員

Awards (3)：

2012/03/22 - Japan Society for Bioscience, Biotechnology, and Agrochemistry Award for the Encouragement of Young Scientists
2008/07/25 - Incentive Award for Young Scientist, Tokai branch of The Society of Synthetic Organic Chemistry, Japan, 2008
2007/08/01 - Japanese Society of Carbohydrate Research Award for Young Scientist

Association Membership(s) (5)：

有機合成化学協会 , 日本農芸化学会 , 日本糖質学会 , 日本化学会 , アメリカ化学会

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