Research theme for competitive and other funds (22):
2023 - 2027 Development of cocktail vaccines against poultry red mites using the recombinant turkey herpesvirus
2023 - 2026 The roles of polymorphism in Meq on the pathogenicity of Marek's disease virus and their application for the vaccine development
2022 - 2026 Construction of animal foamy virus vector and development of enzootic bovine leukosis vaccine
2020 - 2023 The search for the candidate molecule for the vaccine to control a wide range of ectoparasite species of chickens
2020 - 2023 血液脳関門を透過する新規DDSによる神経向性ウイルス感染の治療法開発
2019 - 2023 MHC クラスII DRB3*0902保有牛における牛白血病抵抗性機序
2018 - 2021 Development of a method to control poultry red mites using recombinant Marek's disease virus that secretes a vaccine antigen
2017 - 2020 Analysis of the molecular mechanism for the increase in the virulence of Marek's disease virus
2016 - 2019 Analysis of genetic polymorphism of poultry red mites in the world and search for candidate molecules of anti-mite vaccines
2016 - 2018 Comprehensive analysis of molecules expressed on the midgut of poultry red mites for the development of new anti-mite vaccines
2014 - 2017 Intramammary infusion of food-grade lactic acid bacteria (Bifidobacterium breve) on cellular and immuno-modulatory functions in mammary glands and therapeutic trials on bovine mastitis in dairy cows.
2014 - 2017 Influence of the immune status on the malignancy of canine histiocytic sarcoma
2014 - 2017 Studies on the molecular mechanisms for the increase in MDV virulence in the field
2012 - 2016 Defence mechanism against environmental chemicals in livestock animals
2011 - 2014 Studies on the immunoinhibitory mechanisms of Marek's disease virus and its application for adjuvant
2010 - 2014 Epidemiological and immunological analyzes of spread manner of bovine viral diarrhea virus in the herd
2009 - 2011 Identification and characterization of factors involved in the resistance to Marek' s disease in chickens and wild waterfowls
2008 - 2010 Studies on the molecular mechanisms for Marek's disease virus to increase its virulence in the field
2006 - 2008 Genetic analysis of drug resistant trypanosomes
2006 - 2007 抗糖脂質モノクローナル抗体のイヌ型抗体化とメラノーマ治療への応用
2006 - 2007 ダニの唾液由来免疫抑制因子を用いるダニ媒介性病原体の伝播阻止
2005 - 2007 Tick vaccine development by using tick testis-derived factors
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Papers (291):
Win SY, Seo H, Horio F, Fujisawa S, Sato J, Motai Y, Sato T, Oishi E, Taneno A, Htun LL, et al. In Vivo Characterization of the Anti-Glutathione S-Transferase Antibody Using an In Vitro Mite Feeding Model. Vaccines. 2024. in press
Motai Y, Murata S, Sato J, Nishi A, Maekawa N, Okagawa T, Konnai S, Ohashi K. Characterization of a Very Short Meq Protein Isoform in a Marek's Disease Virus Strain in Japan. Vet Sci. 2024. 11. 1. 43
Moraes B, Martins R, Lopes C, Martins R, Arcanjo A, Nascimento J, Konnai S, da Silva Vaz I Jr, Logullo C. G6PDH as a key immunometabolic and redox trigger in arthropods. Front Physiol. 2023. 14. 1287090
Berger M, Rosa da Mata S, Pizzolatti NM, Parizi LF, Konnai S, da Silva Vaz I Jr, Seixas A, Tirloni L. An Ixodes persulcatus inhibitor of plasmin and thrombin hinders keratinocyte migration, blood coagulation, and endothelial permeability. 2023. S0022-202X(23). 03107
Maekawa N, Konnai S, Hosoya K, Kim S, Kinoshita R, Deguchi T, Owaki R, Tachibana Y, Yokokawa M, Takeuchi H, et al. Safety and clinical efficacy of an anti-PD-L1 antibody (c4G12) in dogs with advanced malignant tumours. PLOS ONE. 2023. 18. 10. e0291727
Immune Checkpoint Inhibitors 〜Breakthrough Cancer Therapy and its Application to Veterinary Medicine 〜
(Seminario Especial in Universidade Federal do Rio Grande do Sul 2024)
THE JAPANESE SOCIETY FOR VIROLOGY
, 大動物臨床研究会
, JAPANESE SOCIETY FOR CLINICAL INFECTIOUS DISEASE IN FARM ANIMALS
, 動物サイトカイン研究会
, 日本獣医寄生虫学会
, 動物用ワクチン-バイオ医薬品研究会
, 北海道獣医師会
, JAPAN VETERINARY MEDICAL ASSOCIATION
, JAPANESE SOCIETY OF VETERINARY SCIENCE