Rchr
J-GLOBAL ID:201201080463438622   Update date: Apr. 19, 2024

KURIHARA Shin

クリハラ シン | KURIHARA Shin
Affiliation and department:
Research field  (2): Bacteriology ,  Applied microbiology
Research keywords  (8): predominant human intestinal bacteria ,  prebiotics ,  Enterococcus faecalis ,  quorum sensing ,  Proteus mirabilis ,  polyamine ,  E. coli ,  Intestinal bacteria
Research theme for competitive and other funds  (21):
  • 2023 - 2027 New strategy for preventing colorectal cancer by targeting polyamines, which are thought to be carcinogens
  • 2023 - 2026 Establishment of technology for intestinal polyamine production by combining non-digestible peptides and bacteria from fermented foods.
  • 2023 - 2026 大豆由来難消化性ペプチドを用いたヒト腸内常在菌叢の改善技術の開発と健康への応用
  • 2023 - 2025 Analysis of the association between polyamine production in the scalp bacterial flora and hair growth.
  • 2021 - 2024 腸内細菌叢が関与する食品中機能性成分の抱合代謝物動態の総合的理解
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Papers (68):
  • Bin Li, Jue Liang, Hamid R Baniasadi, Shin Kurihara, Margaret A Phillips, Anthony J Michael. Functional identification of bacterial spermine, thermospermine, norspermine, norspermidine, spermidine, and N1-aminopropylagmatine synthases. The Journal of biological chemistry. 2024. 107281-107281
  • Rika Hirano, Izumi Nishita, Riho Nakai, Ayaka Bito, Ryunosuke Sasabe, Shin Kurihara. Development of culture methods capable of culturing a wide range of predominant species of intestinal bacteria. Frontiers in Cellular and Infection Microbiology. 2023. 13. 1056866
  • Yuta Ami, Narumi Kodama, Masahiro Umeda, Hanae Nakamura, Hideto Shirasawa, Takashi Koyanagi, Shin Kurihara. Levilactobacillus brevis with high production of putrescine isolated from blue cheese and its application. International Journal of Molecular Sciences. 2023. 24. 11. 9668
  • Hiromi Shimokawa, Mikiyasu Sakanaka, Yuki Fujisawa, Hirokazu Ohta, Yuta Sugiyama, Shin Kurihara. N-carbamoylputrescine amidohydrolase of Bacteroides thetaiotaomicron, a dominant species of the human gut microbiota. Biomedicines. 2023. 11. 4. 1123
  • Hideto Shirasawa, Chisato Nishiyama, Rika Hirano, Takashi Koyanagi, Shujiro Okuda, Hiroki Takagi, Shin Kurihara. Isolation of the high polyamine-producing bacterium Staphylococcus epidermidis FB146 from fermented foods and identification of polyamine-related genes. Bioscience of Microbiota, Food and Health. 2023. 42. 1. 24-33
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MISC (34):
  • 杉山 友太, 栗原 新. 腸内細菌由来フェネチルアミンによる宿主セロトニン産生の促進. バイオサイエンスとインダストリー. 2023. 81. 4. 305-307
  • 平野 里佳, 中井 博之, 栗原 新. 【オリゴ糖研究の最前線 その2】腸内細菌一斉培養システムを用いたオリゴ糖の資化性評価. 応用糖質科学. 2023. 12. 4. 203-208
  • 児玉成美, 中村花恵, 白澤秀斗, 梅田雅大, 小柳喬, 栗原新. Development of polyamine-containing beverages using high polyamine-producing bacteria derived from fermented foods. 日本ポリアミン学会年会プログラム及び抄録集. 2023. 13th
  • 中村篤央, 生田かよ, 久米愛子, 栗原新, 長谷耕二, 松本光晴. Effects of putrescine produced by intestinal bacteria on intestinal permeability. 日本ポリアミン学会年会プログラム及び抄録集. 2023. 13th
  • 栗原新. Analysis of the Effect of Soybean-derived Indigestible Peptides on Polyamine Production by Gut Indigenous Bacteria. 大豆たん白質研究. 2023. 25
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Patents (7):
  • 末梢セロトニンまたは腸内芳香族アミンの増加を伴う疾患の予防または治療用医薬組成物および末梢セロトニンまたは腸内芳香族アミンの増加を伴う疾患の予防または治療用薬剤のスクリーニング方法
  • Group media for gut bacteria, and method of culturing gut bacteria
  • タマリンド分解物、酪酸産生菌増殖促進剤、腸内酪酸産生用組成物、並びに、タマリンド分解物の製造方法
  • 腸内ポリアミン産生剤
  • サポニンを含む酪酸産生菌増殖能向上組成物、腸内常在菌増殖能向上組成物、乳酸菌増殖能向上組成物及びビフィズス菌増殖能向上組成物
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Books (2):
  • 微生物資源の整備と利活用の戦略
    エヌ・ティー・エス 2023 ISBN:9784860438586
  • 醸造の事典 = Encyclopedia of jozo
    朝倉書店 2021 ISBN:9784254431254
Lectures and oral presentations  (185):
  • タマリンドシードガム酵素分解物は、ヒト腸内常在酪酸産生菌Roseburia intestinalisを特異的に増殖促進させ腸内の酪酸増加に寄与する
    (日本乳酸菌学会誌 2023)
  • ブルーチーズ由来高ポリアミン産生乳酸菌Levilactobacillus brevis FB215の分離と応用
    (日本乳酸菌学会誌 2023)
  • Intestinal microbes convert arginine, which is a component of the resistant protein, into putrescine.
    (2023 Polyamines Conference GRC 2023)
  • Extension of host lifespan by polyamines derived from gut bacteria
    (2023 Polyamines Conference GRC 2023)
  • Development of polyamine-containing beverages using high polyamine-producing bacteria derived from fermented foods
    (日本ポリアミン学会年会プログラム及び抄録集 2023)
more...
Education (3):
  • 2003 - 2006 Kyoto University Graduate School of Biostudies
  • 2001 - 2003 Kyoto University Graduate School of Biostudies Applied Life Sciences
  • 1997 - 2001 Kyoto University Faculty of Agriculture
Professional career (1):
  • Ph.D. (Life science) (Kyoto University)
Work history (11):
  • 2021/04 - 現在 Kindai University Faculty of Biology-Oriented Science and Technology Department of Science and Technology on Food Safety Associate Professor
  • 2019/04 - 2021/03 Kindai University Faculty of Biology-Oriented Science and Technology Department of Science and Technology on Food Safety Lecturer
  • 2013/10 - 2019/03 Ishikawa Prefectural University Host-Microbe Interaction Research Lab Associate Professor
  • 2013/09 - 2013/09 Ishikawa Prefectural University Research Institute for Bioresources and Biotechnology Postdoc
  • 2013/03 - 2013/08 University of Texas Southwestern Medical Center, Dallas Department of Pharmacology Visiting Senior Researcher
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Committee career (3):
  • 2023/07 - 現在 Japan Society for Lactic Acid Bacteria. director
  • 2018/12 - 現在 日本ポリアミン学会 評議員
  • 2017/05 - 現在 日本ポリアミン学会 企画運営委員
Awards (11):
  • 2023/07 - 一般社団法人バイオインダストリー協会 バイオインダストリー奨励賞 日欧ヒト腸内常在菌叢における最優勢種のハイスループット培養・解析法の開発と応用
  • 2023/04 - Japan Society for Bioscience, Biotechnology, and Agrochemistry Hot Topics Award at Annual Meeting of JSBBA 2023 Intestinal microbes can convert arginine in soy-derived digestion resistant peptide to polyamines.
  • 2020/01 - 日本農芸化学会 2020年度大会 トピックス演題選出(発表責任者) 次世代型プレバイオティクス・ガラクトシル-β-1,4-ラムノースのビフィズス菌特異的な増殖促進機構の解析
  • 2019/03 - Japan Society for Bioscience, Biotechnology, and Agrochemistry JSBBA Award for Young Scientists Elucidation of polyamine metabolism and transport by the gut microbes
  • 2018/03 - BBB paper award (Corresponding author) Use of Gifu Anaerobic Medium for culturing 32 dominant species of human gut microbes and its evaluation based on short-chain fatty acids fermentation profiles.
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