HAMADA Michito

ハマダミチト | HAMADA Michito

Affiliation and department：
Job title： Associate Professor

Research field (2)： Immunology , Medical biochemistry

Research theme for competitive and other funds (9)：

2021 - 2024 Ym1陽性単球由来マクロファージによる肝線維症の進展機序解明
2019 - 2022 Analysis of the regulatory mechanism of macrophages involved in homeostasis by the transcription factor MafB
2019 - 2022 Development of real time in vivo imaging method that can monitor tissue inflammation and fibrosis.
2017 - 2020 Immune regulation by dead intestinal epithelial cells
2018 - 2020 転写因子MafBの脾臓での腫瘍随伴マクロファージ数の制御機構の解明

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Papers (56)：

Kanai, Maho, Nishino, Teppei, Daassi, Dhouha, Kimura, Akari, Liao, Ching-Wei, Shahri, Zeynab Javanfekr, Wakimoto, Arata, Gogoleva, Natalia, USUI, Toshiaki, Morito, Naoki, et al. MAFB in Macrophages Regulates Prostaglandin E2-Mediated Lipid Mediator Class Switch through ALOX15 in Ischemic Acute Kidney Injury. The Journal of Immunology. 2024
Manoj Kumar Yadav, Megumi Ishida, Natalia Gogoleva, Ching-Wei Liao, Filiani Natalia Salim, Maho Kanai, Akihiro Kuno, Takuto Hayashi, Zeynab Javanfekr Shahri, Kaushalya Kulathunga, et al. MAFB in macrophages regulates cold-induced neuronal density in brown adipose tissue. Cell reports. 2024. 43. 4. 113978-113978
Takeshi Kawamata, Arata Wakimoto, Takanobu Nishikawa, Masaya Ikezawa, Michito Hamada, Yuri Inoue, Kaushalya Kulathunga, Filiani Natalia Salim, Maho Kanai, Teppei Nishino, et al. Natto consumption suppresses atherosclerotic plaque progression in LDL receptor-deficient mice transplanted with iRFP-expressing hematopoietic cells. Scientific reports. 2023. 13. 1. 22469-22469
Gogoleva, Natalia, Shahri, Zeynab Javanfekr, Noda, Atsushi, Liao, Ching-Wei, Wakimoto, Arata, Inoue, Yuri, Jeon, Hyojung, Takahashi, Satoru, Hamada, Michito. Intraplacental injection of AAV9-CMV-iCre results in the widespread transduction of multiple organs in double-reporter mouse embryos. EXPERIMENTAL ANIMALS. 2023. 72. 4. 460-467
Hayashi, Takuto, Fujita, Ryo, Okada, Risa, Hamada, Michito, Suzuki, Riku, Fuseya, Sayaka, Leckey, James, Kanai, Maho, Inoue, Yuri, Sadaki, Shunya, et al. Lunar gravity prevents skeletal muscle atrophy but not myofiber type shift in mice. COMMUNICATIONS BIOLOGY. 2023. 6. 1. 424

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MISC (21)：

Usui, Toshiaki, Morito, Naoki, Ishibashi, Shun, Gogoleva, Natalia, Kanai, Maho, Inoue, Yuri, Fuseya, Sayaka, Kuno, Akihiro, Mizuno, Seiya, Hamada, Michito, et al. EFFECTIVENESS OF IMATINIB FOR MCTO NEPHROPATHY. NEPHROLOGY DIALYSIS TRANSPLANTATION. 2023. 38. 1. I258-I258
Inoue, Y, Hamada, M, Takahashi, S. THE TRANSCRIPTION FACTOR MAFB EXPRESSED IN MACROPHAGES PROMOTE WOUND HEALING. WOUND REPAIR AND REGENERATION. 2022. 30. 4. A11-A11
Kulathunga, Kaushalya, Wakimoto, Arata, Hamada, Michito, Takahashi, Satoru. Tyrosinase mutations, a novel predisposing genetic factor for enhanced non-alcoholic steatohepatitis susceptibility. JOURNAL OF HEPATOLOGY. 2022. 77. 1. S702-S703
池田祥久, 池田祥久, 久野朗広, 綾部信哉, 坂本航太郎, 鈴木沙耶香, 森本健斗, 脇本新, 三上夏輝, DINH THI Huong Tra, et al. CRISPR-Casベースのゲノム編集結果を検証するためのDAJIN-assisted multiplex genotyping. 日本実験動物学会総会講演要旨集(Web). 2021. 68th
USUI, Toshiaki, Morito, Naoki, Tsunakawa, Yuki, JEON, Hyojung, Hamada, Michito, Mizuno, Seiya, Takahashi, Satoru, Yamagata, Kunihiro. ANALYSIS OF A MOUSE MODEL FOR MCTO DUE TO THE MUTATION OF MAFB TRANSACTIVATION DOMAIN. Nephrology Dialysis Transplantation. 2020. 35. 3. 134-134

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Patents (2)：

非ヒト動物及びその製造方法
非ヒト動物及びその製造方法

Books (7)：

医学のあゆみ
2018
セラピューティック・リサーチ
2014
Functions of the large maf transcription factors and macrophages
Springer New York 2014
第6章 Maf
「モデル動物利用マニュアル」シリーズ疾患モデルの作製と利用がん 2012
The Mouse Genome Informatics (MGI) MGIの便利な使い方
細胞工学別冊「バイオリソース&データベース活用術 Webでキャッチ!!実験材料・インフォマティクス」 2009

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Lectures and oral presentations (79)：

多中心性手根足根骨溶解症(MCTO)関連腎症に対するMAFB-IGF1-PI3K/AKTシグナル抑制は潜在的な治療選択肢である
(第67回日本腎臓学会学術総会)
EFFECTIVENESS OF IMATINIB FOR MCTO NEPHROPATHY
(60th ERA Congress)
Effectiveness of Imatinib Formcto Nephropathy
(60th ERA Congress)
ポドサイト特異的MafB活性化物質のハイスループットスクリーニングの確立
(第66回日本腎臓学会学術総会)
速筋線維の形成に不可欠な新規制御因子である大Maf転写因子の機能解析
(日本分子生物学会年会 2022)

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Education (3)：

2003 - 2007 University of Tsukuba
2001 - 2003 University of Tsukuba
1997 - 2001 Ibaraki University

Professional career (1)：

博士(医学) (筑波大学)

Work history (2)：

2009/04 - 現在筑波大学大学院人間総合科学研究科助教
2007/05 - 2009/03 筑波大学大学院人間総合科学研究科研究員 (文部科学省ゲノムネットワークプロジェクト)

Committee career (1)：

2019/07 - 現在 Scientific Reports (Nature Publishing Group) Editorial Board Member

Awards (6)：

2019/12 - 教員業績評価教育
2018/05 - 公益財団法人日本実験動物学会平成30年(公社)日本実験動物学会奨励賞マクロファージにおけるMafBの機能解析
2016/12 - 第45回日本免疫学会ベストプレゼンテーション賞
2016/12 - 教員業績評価教育
2015/12 - 教員業績評価研究

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Association Membership(s) (6)：

日本骨免疫学会 , 公益財団法人日本生化学会 , JAPANESE SOCIETY FOR IMMUNOLOGY , The Japanese Association of Anatomists , 日本実験動物学会 , The Molecular Biology Society of Japan

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