Research field (2):
Synthetic organic chemistry
, Pharmaceuticals - chemistry and drug development
Research keywords (14):
proton transfer reaction
, atom economy
, 光触媒
, 前周期遷移金属
, Alkaline earth metal
, 触媒反応
, 不斉反応
, 炭素ー炭素結合生成
, 不活性炭素-水素結合
, 不斉配位子
, 低酸性求核剤前駆体
, Alkaline metal
, ルイス酸
, 強塩基
Research theme for competitive and other funds (10):
2022 - 2027 Organic chemistry using water: development of aqua-organic chemistry
2017 - 2022 Development of Strong Bronsted Base Hybrid Catalyst Systems for Stereoselective Carbon-Carbon Bond Forming Reactions
2016 - 2018 The Design and Application of Highly Modified Chiral Alkaline Metal Complexes as Strong Base Catalysts for Highly Stereoselective Reactions
2013 - 2015 生成物を塩基とする新触媒サイクルによる分子骨格構築反応の開発
2012 - 2014 Development of catalytic direct addition reactions of unprotected aminoalkanes
2008 - 2009 イオン液体を活用する水中での高効率触媒反応
2008 - 2009 NOカチオンを触媒として活用する有機合成反応の開発研究
2003 - 2004 光学活性ジルコニウム、ニオブ、タンタル触媒の開発と医薬品合成への展開
2002 - 2004 Development of Benign Chemical Processes on Nano-seized Reaction Environments
1999 - 2001 Development of New icroencapsulated Polymer-Supported Catalysts
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Papers (127):
Yasuhiro Yamashita, Shu Kobayashi. Efficient Radical-mediated Intermolecular α-Alkylation Reactions of Carbonyl Compounds with Nonactivated Alkenes. Chemistry, an Asian journal. 2024. e202400319
Yasuhiro Yamashita, Seiya Fushimi, Trisha Banik, Tomoya Kimura, Shu Kobayashi. Development of Catalytic Enantioselective Mannich Reactions Using Esters. Organic letters. 2024. 26. 8. 1579-1583
Julie Kong, Charlie Lacroix, Chloée Bournaud, Yasuhiro Yamashita, Shū Kobayashi, Giang Vo-Thanh. Enantioselective Acyl-Transfer/Protonation Reactions with Designed Chiral Thiourea-Iminophosphorane Catalysts. Advanced Synthesis & Catalysis. 2024. 366. 5. 1101-1106
Airu Hashidoko, Taku Kitanosono, Yasuhiro Yamashita, Shu Kobayashi. Water vs. Organic Solvents: Water-Controlled Divergent Reactivity of 2-Substituted Indoles. Chemistry, an Asian journal. 2024. e202301045
Tsubasa Hirata, Tomoya Hisada, Yoshihiro Ogasawara, Shu Kobayashi, Yasuhiro Yamashita. Development of Photoredox-assisted Direct a-Alkylation Reactions of Ketones with Arylalkenes using a Catalytic Amount of LiO t Bu as a Brønsted Base. Helvetica Chimica Acta. 2023
Photoinduced α-alkylation reactions of carbonyl compounds with alkenes
(The Catalysis and Sensing for our Environment (CASE) Symposium 2024 at The Univ. of Tokyo (CASE 2024) 2024)
New Dimension of Brønsted Base-catalyzed Carbon-Carbon Bond Forming Reactions
(5th International Symposium on Catalysis Toward Green Sustainable Chemistry (CAT-GSC-5) 2023)
Development of Chiral Strong Brønsted Base Catalyst Systems for Enantioselective Carbon-Carbon Bond Forming Reactions
(The 3rd International Symposium on Hybrid Catalysis for Enabling Molecular Synthesis on Demand 2022)
新規高機能アルカリ金属強塩基触媒系の開発と展開
(国際医薬品開発展2022 2022)
Development of Chiral Potassium Strong Base Catalysts for Enantioselective Carbon-Carbon Bond Forming Reactions
(Pacifichem 2021 2021)