Kodama Tetsuya

Affiliation and department：
Job title： Associate professor

Research field (1)： Pharmaceuticals - chemistry and drug development

Research keywords (1)：化学系薬学創薬化学核酸化学生体関連化学生物分子化学

Research theme for competitive and other funds (11)：

2017 - 2019 生体安定性と毒性低減とを志向した、糖部とリン酸部の構造制御による人工核酸設計
2014 - 2017 次世代核酸医薬の開発を志向した三重鎖形成核酸創製基盤の構築
2012 - 2016 Development of platform technologies for antisense oligonucleotide-based therapeutics by a combination of nucleic acids chemistry and information sciences
2010 - 2015 Development of synthetic methodology to supply materials for understanding of physiological system
2012 - 2014 核酸塩基の回転角制御に基づく人工核酸創製法に関する研究

Show all

Papers (42)：

Moai Y, Hiroaki H, Obika S, Kodama T. Synthesis of selenomethylene-locked nucleic acids (SeLNA) nucleoside unit bearing an adenine base. Nucleosides, nucleotides & nucleic acids. 2019. 1-10
中野篤志, 牧野亜衣, 廣明秀一, 兒玉哲也. N型立体配座に制御した2',5'-結合核酸の合成と特性評価に関する研究. 日本薬学会年会要旨集. 2019. 139年会. 2. 101-101
Seiji Ishii, Kenji Fukui, Satoshi Yokoshima, Kazuo Kumagai, Youko Beniyama, Tetsuya Kodama, Tohru Fukuyama, Takayoshi Okabe, Tetsuo Nagano, Hirotatsu Kojima, et al. High-throughput Screening of Small Molecule Inhibitors of the Streptococcus Quorum-sensing Signal Pathway. SCIENTIFIC REPORTS. 2017. 7. 4029
Takashi Hara, Tetsuya Kodama, Yumi Takegaki, Kunihiko Morihiro, Kosuke Ramon Ito, Satoshi Obika. Synthesis and Properties of 7-Deazapurine- and 8-Aza-7-deazapurine-Locked Nucleic Acid Analogues: Effect of the Glycosidic Torsion Angle. Journal of Organic Chemistry. 2017. 82. 1. 25-36
Smita Nahar, Amrita Singh, Kunihiko Morihiro, Yoshihiro Moai, Tetsuya Kodama, Satoshi Obika, Souvik Maiti. Systematic Evaluation of Biophysical and Functional Characteristics of Selenomethylene-Locked Nucleic Acid-Mediated Inhibition of miR-21. BIOCHEMISTRY. 2016. 55. 50. 7023-7032

ｍore...

MISC (16)：

ｍore...

Lectures and oral presentations (33)：

核酸コンジュゲートの戦略と合成
(GTRコンソーシアムワークショップ 2024)
糖部構造を刷新した人工核酸の設計と合成
(第2回 BINDS 合成勉強会 2019)
歪んだトランス縮環骨格を糖部骨格とするヌクレオシド類の合成
(第113回有機合成シンポジウム2018年 2018)
Syntheitc study of an N3'->P5' phosphoramidate-type nucleic acid
(The 44th International Symposium on Nucleic Acids Chemistry 2017, The 1st Annual Meeting of Japan Society of Nucleic Acids Chemistry 2017)
二面角ガンマを固定した 2ʼ-5ʼ 連結型核酸分子含有オリゴ核酸の合成とその二重鎖、三重鎖核酸の安定性
(日本核酸医薬学会第2回年会 2016)

ｍore...

Education (2)：

Professional career (1)：

Work history (4)：

2012/04/01 - 現在 Nagoya University Graduare School of Pharmaceutical Sciences
2012/04/01 - 現在 Nagoya University Graduate School of Pharmaceutical Sciences Department of Basic Medicinal Sciences Structural Biology Associate professor
2007/04/01 - 2012/03/31 Osaka University Graduate School of Pharmaceutical Sciences
2006/04/01 - 2007/03/31 Osaka University Graduate School of Pharmaceutical Sciences

Association Membership(s) (6)：

日本核酸化学会 , アンチセンスDNA/RNA研究会 , 日本核酸医薬学会 , 有機合成化学協会 , 日本化学会 , 日本薬学会

※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

Return to Previous Page