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J-GLOBAL ID:201201088515259412   Update date: Aug. 31, 2021

Miyoshi Hiromi

ミヨシ ヒロミ | Miyoshi Hiromi
Affiliation and department:
Job title: 准教授
Homepage URL  (1): http://www.comp.sd.tmu.ac.jp/appliedmechanobio/
Research field  (3): Biomaterials ,  Biomedical engineering ,  Biophysics
Research keywords  (5): 微細構造化基板 ,  バイオイメージング ,  メカノバイオロジー ,  細胞極性 ,  アクチン
Research theme for competitive and other funds  (4):
  • 2015 - 2019 ナノ構造による遺伝情報選択制御の力学機構の理解と幹細胞分化制御への応用展開
  • 2012 - 2013 ラベルフリー、非侵襲的な細胞ソーティングのための機能性マイクロ構造化表面のオーダーメイド設計手法の確立
  • 2011 - 2012 標的細胞をラベルフリーで識別・分離し非侵襲的に収集するためのマイクロチップの設計
  • 2008 - 2010 力学的、分子的両観点からの細胞分裂の解析
Papers (25):
  • Tomoko Gowa Oyama, Kotaro Oyama, Hiromi Miyoshi, Mitsumasa Taguchi. 3D cell sheets formed via cell-driven buckling-delamination of patterned thin films. Materials & Design. 2021. 109975-109975
  • Tomoko G Oyama, Kotaro Oyama, Atsushi Kimura, Fumiya Yoshida, Ryo Ishida, Masashi Yamazaki, Hiromi Miyoshi, Mitsumasa Taguchi. Collagen hydrogels with controllable combined cues of elasticity and topography to regulate cellular processes. Biomedical Materials. 2021. 16. 4. 045037-045037
  • Masashi Yamazaki, Satoru Kidoaki, Hiromichi Fujie, Hiromi Miyoshi. Designing elastic modulus of cell culture substrate to regulate YAP and RUNX2 localization for controlling differentiation of human mesenchymal stem cells. Analytical Sciences. 2021. 37. 3. 447-453
  • Masashi YAMAZAKI, Hiromichi FUJIE, Hiromi MIYOSHI. Mechanical interaction between actin cytoskeleton and nucleus regulates intracellular YAP localization in osteogenic differentiation in human mesenchymal stem cells. Transactions of the JSME (in Japanese). 2020. 86. 890. 20-00264
  • Masashi Yamazaki, Hiroki Kojima, Hiromi Miyoshi. Morphology and Differentiation of Human Mesenchymal Stem Cells Cultured on a Nano-Scale Structured Substrate. Electronics and Communications in Japan. 2020. 103. 9. 23-28
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MISC (43):
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Patents (10):
  • 間葉系幹細胞集団の骨芽細胞分化ポテンシャルの予測方法
  • 細胞培養器材、細胞付細胞培養器材、及び細胞シートの製造方法
  • 細胞識別装置、細胞識別方法及びプログラム
  • 未分化細胞の分離方法及び未分化細胞分離用基板
  • 細胞培養用基板および間葉系幹細胞の分化制御方法
more...
Books (2):
  • Smart design of materials for tissue engineering” Smart Materials for Tissue Engineering: Fundamental Principles
    Royal Society of Chemistry 2016
  • Innovative Approaches to Cell Biomechanics: From Cell Migration to On-Chip Manipulation
    Springer 2015
Lectures and oral presentations  (15):
  • Actin cytoskeletal forces to regulate osteoblastic differentiation in mesenchymal stem cell
    (2020)
  • 組織・細胞培養基材表面設計の基礎を支えるメカノバイオロジー-間葉系幹細胞の分化に対するアクチン細胞骨格の力の寄与-
    (応用物理学会 有機分子バイオエレクトロニクス分科会研究会 「有機分子・バイオエレクトロニクスの未来を観る」 2018)
  • Microtopographical cell culture substrate to understand the role of actin cytoskeleton for regulation of gene expression
    (The 55th Annual Meeting of The Biophysical Society of Japan 2017)
  • Change in the intranuclear DNA organization during human mesenchymal stem cell differentiation
    (The 3rd Africa International Biotechnology and Biomedical conference 2017)
  • The Effects of Microgrooved Structures on Cell shape and Actomyosin Organization
    (7th International Conference on Computational Methods 2016)
more...
Education (1):
  • 2003 - 2006 Tokyo Institute of Technology
Professional career (1):
  • Ph.D. (Tokyo Institute of Technology)
Work history (5):
  • 2020/04 - 現在 Tokyo Metropolitan University Faculty of Systems Design Associate Professor
  • 2017/04 - 2020/03 Tokyo Metropolitan University Faculty of Systems Design Associate Professor
  • 2016/04 - 2017/03 RIKEN
  • 2007/04 - 2016/03 RIKEN
  • 2006/04 - 2007/03 New Energy and Industrial Technology Development Organization NEDO fellow
Awards (7):
  • 2021/03 - Analytical Sciences Hot Article Award Analytical Sciences "Designing elastic modulus of cell culture substrate to regulate YAP and RUNX2 localization for controlling differentiation of human mesenchymal stem cells"
  • 2017/03 - 2017 JBSE Graphics of the year award
  • 2017/03 - Journal of Biomechanical Science and Engineering 2017 JBSE papers of the year award
  • 2016/03 - 理化学研究所 産業連携奨励賞
  • 2014/06 - 資生堂 女性研究者サイエンスグラント
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Association Membership(s) (5):
THE JAPAN SOCIETY OF MECHANICAL ENGINEERS ,  THE JAPANESE SOCIETY FOR REGENERATIVE MEDICINE ,  JAPAN SOCIETY FOR CELL BIOLOGY ,  THE BIOPHYSICAL SOCIETY OF JAPAN ,  Biophysical Society
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