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J-GLOBAL ID:201201088515259412   Update date: Jun. 13, 2024

Miyoshi Hiromi

ミヨシ ヒロミ | Miyoshi Hiromi
Affiliation and department:
Job title: 准教授
Homepage URL  (1): http://www.comp.sd.tmu.ac.jp/appliedmechanobio/
Research field  (3): Biomaterials ,  Biomedical engineering ,  Biophysics
Research keywords  (5): 微細構造化基板 ,  バイオイメージング ,  メカノバイオロジー ,  細胞極性 ,  アクチン
Research theme for competitive and other funds  (7):
  • 2020 - 2023 Foundation of Oil Behavior analyzed by Multiscale Fluid Simulations
  • 2021 - 2022 眼老化・疾患予防の高度化のための調光技術の社会実装に向けた可視光の細胞毒性評価法による基礎的検討
  • 2018 - 2021 Study on the role of the mechanical dynamics in the nucleus in cellular mechanical responses
  • 2015 - 2019 ナノ構造による遺伝情報選択制御の力学機構の理解と幹細胞分化制御への応用展開
  • 2012 - 2013 ラベルフリー、非侵襲的な細胞ソーティングのための機能性マイクロ構造化表面のオーダーメイド設計手法の確立
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Papers (34):
  • Go Uchida, Hitoshi Washizu, Hiromi Miyoshi. Diffusion with a broad class of stochastic diffusion coefficients. Physical Review E. 2024. 109. 6
  • Hiromi Miyoshi, Masashi Yamazaki, Hiromichi Fujie, Satoru Kidoaki. Guideline for design of substrate stiffness for mesenchymal stem cell culture based on heterogeneity of YAP and RUNX2 responses. Biophysics and Physicobiology. 2023. 20. 2. n/a-n/a
  • Ryosuke Nishimura, Kagayaki Kato, Misako Saida, Yasuhiro Kamei, Masahiro Takeda, Hiromi Miyoshi, Yutaka Yamagata, Yu Amano, Shigenobu Yonemura. Appropriate tension sensitivity of α-catenin ensures rounding morphogenesis of epithelial spheroids. Cell Structure and Function. 2022. 47. 2. 55-73
  • Naoya SAKAMOTO, Kohei TATEBAYASHI, Hiromi MIYOSHI. Endothelial differentiation of mesenchymal stem cells induced by the combined mechanical stimulation of wall shear stress and cyclic strain. Transactions of the JSME (in Japanese). 2022. 88. 911. 22-00103-00103
  • Kojiro Matsushita, Chiharu Nakahara, Shun Kimura, Naoya Sakamoto, Satoshi Ii, Hiromi Miyoshi. Intranuclear mesoscale viscoelastic changes during osteoblastic differentiation of human mesenchymal stem cells. The FASEB Journal. 2021. 35. 12. e22071
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MISC (63):
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Patents (11):
  • 細胞判定構造体、細胞判定装置、細胞判定方法、及びプログラム
  • 間葉系幹細胞集団の骨芽細胞分化ポテンシャルの予測方法
  • 細胞培養器材、細胞付細胞培養器材、及び細胞シートの製造方法
  • 細胞識別装置、細胞識別方法及びプログラム
  • 未分化細胞の分離方法及び未分化細胞分離用基板
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Books (3):
  • 三次元組織モデルの実現に向けた柔軟な培養基材の開発
    2022
  • Smart design of materials for tissue engineering” Smart Materials for Tissue Engineering: Fundamental Principles
    Royal Society of Chemistry 2016
  • Innovative Approaches to Cell Biomechanics: From Cell Migration to On-Chip Manipulation
    Springer 2015
Lectures and oral presentations  (15):
  • Actin cytoskeletal forces to regulate osteoblastic differentiation in mesenchymal stem cell
    (2020)
  • 組織・細胞培養基材表面設計の基礎を支えるメカノバイオロジー-間葉系幹細胞の分化に対するアクチン細胞骨格の力の寄与-
    (応用物理学会 有機分子バイオエレクトロニクス分科会研究会 「有機分子・バイオエレクトロニクスの未来を観る」 2018)
  • Microtopographical cell culture substrate to understand the role of actin cytoskeleton for regulation of gene expression
    (The 55th Annual Meeting of The Biophysical Society of Japan 2017)
  • Change in the intranuclear DNA organization during human mesenchymal stem cell differentiation
    (The 3rd Africa International Biotechnology and Biomedical conference 2017)
  • The Effects of Microgrooved Structures on Cell shape and Actomyosin Organization
    (7th International Conference on Computational Methods 2016)
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Education (3):
  • 2003 - 2006 Tokyo Institute of Technology Department of Life Science and Technology
  • 1998 - 2000 Tokyo Institute of Technology
  • 1994 - 1998 Tokyo Institute of Technology School of Bioscience and Biotechnology
Professional career (1):
  • Ph.D. (Tokyo Institute of Technology)
Work history (5):
  • 2020/04 - 現在 Tokyo Metropolitan University Faculty of Systems Design Associate Professor
  • 2017/04 - 2020/03 Tokyo Metropolitan University Faculty of Systems Design Associate Professor
  • 2016/04 - 2017/03 RIKEN
  • 2007/04 - 2016/03 RIKEN
  • 2006/04 - 2007/03 New Energy and Industrial Technology Development Organization NEDO fellow
Awards (9):
  • 2023/07 - 第62回日本白内障学会,第49回水晶体研究会 セッション優秀賞 ヒト水晶体上皮細胞の微細間隙への 浸潤性に対する可視域の光の関与
  • 2022/10 - 公益社団法人日本生体医工学会 生体医工学シンポジウムベストレビュワーアワード
  • 2021/03 - Analytical Sciences Hot Article Award Analytical Sciences "Designing elastic modulus of cell culture substrate to regulate YAP and RUNX2 localization for controlling differentiation of human mesenchymal stem cells"
  • 2017/03 - 2017 JBSE Graphics of the year award
  • 2017/03 - Journal of Biomechanical Science and Engineering 2017 JBSE papers of the year award
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Association Membership(s) (5):
THE JAPAN SOCIETY OF MECHANICAL ENGINEERS ,  THE JAPANESE SOCIETY FOR REGENERATIVE MEDICINE ,  JAPAN SOCIETY FOR CELL BIOLOGY ,  THE BIOPHYSICAL SOCIETY OF JAPAN ,  Biophysical Society
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