Hirohara Shiho

ヒロハラシホ | Hirohara Shiho

Affiliation and department：
Homepage URL (1)： http://u-search.ube-k.ac.jp/tc-data/14672

Research field (1)： Biochemistry

Research keywords (5)：がん医療 , tumor selectivity , porphyrin , Positron Emission Tomography , photodynamic therapy

Research theme for competitive and other funds (23)：

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Papers (73)：

Ev. ALA-Porphyrin Science. 2019. 7. 2. 13-23
Kazutaka Hirakawa, Dongyan Ouyang, Yuko Ibuki, Shiho Hirohara, Shigetoshi Okazaki, Eiji Kono, Naohiro Kanayama, Jotaro Nakazaki, Hiroshi Segawa. Photosensitized Protein-Damaging Activity, Cytotoxicity, and Antitumor Effects of P(V)porphyrins Using Long-Wavelength Visible Light through Electron Transfer. Chemical Research in Toxicology. 2018. 31. 5. 371-379
Arif Fadlan, Hiroki Tanimoto, Tatsuya Ito, Yusuke Aritomi, Maho Ueno, Masaya Tokuda, Shiho Hirohara, Makoto Obata, Tsumoru Morimoto, Kiyomi Kakiuchi. Synthesis, photophysical properties, and photodynamic activity of positional isomers of TFPP-glucose conjugates. Bioorganic and Medicinal Chemistry. 2018. 26. 8. 1848-1858
Makoto Obata, Shuto Tanaka, Hiroshi Mizukoshi, Eika Ishihara, Masaki Takahashi, Shiho Hirohara. RAFT Synthesis of Polystyrene-block-Poly(polyethylene glycol monomethyl ether acrylate) for Zinc Phthalocyanine-loaded Polymeric Micelles as a Photosensitizer for Photodynamic Therapy. Journal of Polymer Science: Part A: Polymer Chemistry. 2018. 56. 560-570
Makoto Obata, Shuto Tanaka, Hiroshi Mizukoshi, Eika Ishihara, Masaki Takahashi, Shiho Hirohara. RAFT synthesis of an amphiphilic block copolymer bearing chlorin rings in the hydrophobic segment and its application in photodynamic therapy. JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY. 2017. 55. 20. 3395-3403

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MISC (35)：

廣原志保. <Proceedings> 1 光化学ガン医療のための糖連結ポルフィリンの開発. THE 37TH ANNUAL MEETING OF THE JAPANEASE SOCIETY FOR PHOTOMEDICINE AND PHOTOBIOLOGY, 44. 2015
FUJITSU KYOSUKE, AKAHOSHI HAYATO, SHIRAISHI MASAHIRO, OBATA MAKOTO, MATSUI HIROFUMI, TAMURA MASATO, ITO HIROMU, HIROHARA SHIHO. SOD製剤のための糖連結ポルフィリンマンガン錯体の合成と物性評価. 日本化学会講演予稿集. 2014. 94th. 4. 1340
AKAHOSHI HAYATO, ITO YUMIKO, OBATA MAKOTO, MATSUI HIROFUMI, TAMURA MASATO, HIROHARA SHIHO. 2種類の置換基を導入したクロリンパラジウム錯体の開発. 日本化学会講演予稿集. 2014. 94th. 3. 886
廣原志保. <Proceedings> 2 Hybrid polyion complex gel of succinylated poly (prohypgly) and chitosan and its feasibility study as threedimensional scaffold (査読有). JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE, 8 (SI), 355-356. 2014
FUJITAKE KASUMI, TAMURA MASATO, MATSUI HIROFUMI, HIROHARA SHIHO. 様々な癌細胞株を用いた糖連結ポルフィリンのPDT試験. 日本化学会中国四国支部大会講演要旨集. 2013. 2013. 224

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Patents (2)：

Books (4)：

Spectroscopic Tools for the Diagnosis and Treatment of Cancer; Pacifichem Symposium, Chapter (8)
Sankeisha Co Ltd. 2017
Spectroscopic Tools for the Diagnosis and Treatment of Cancer; Pacifichem Symposium, Chapter (10)
Sankeisha Co Ltd. 2017
光ナノ科学への招待
化学同人全119頁 2010
糖鎖が拓く新たな光がん治療薬
月刊化学全2頁 2010

Lectures and oral presentations (24)：

2つの置換基を有するポルフィリンセラノスティクス薬剤の創成
(第8回ポルフィリン-ALA 学会年会 2018)
TFPC(mEt)4の PDT 評価
(第8回ポルフィリン-ALA 学会年会 2018)
糖連結ポルフィリンの取り込み機構の検討
(第8回ポルフィリン-ALA 学会年会 2018)
PDT 薬剤としての 2 つの置換体を有するクロリンの物性評価
(第8回ポルフィリン-ALA 学会 2018)
がん医療の創成~がん予防、診断、治療のための薬剤開発
(平成29年度第4ブロック研究推進モデル校成果報告会 2018)

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Education (1)：

2001 - 2005 Nara Women's University Graduate School of Humanities and Sciences School of Human Environmental Sciences

Professional career (1)：

Work history (8)：

2016/04 - 現在 Ube National College of Technology Department of Chemical and Biological Engineering
2017/06 - 2020/05 宇部高専テックアンドビジネスコラボレイト(T&B) 副会長
2017/04 - 2020/03 Ube National College of Technology
2012/04 - 2016/03 Ube National College of Technology Department of Chemical and Biological Engineering
2007/10 - 2012/03 Nara Institute of Science and Technology Graduate School of Materials Science

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Committee career (5)：

Awards (3)：

2021/10 - encouragement award Development of porphyrin derivatives for theranostics
2016/03 - 宇部工業高等専門学校平成27年度宇部工業高等専門学校教員表彰(研究)
2015/04 - ポルフィリン-ALA学会第5回ポルフィリン-ALA学会奨励賞

Association Membership(s) (6)：

ヨウ素学会 , DDS学会 , 生体機能関連化学部会 , ポルフィリンALA学会 , PDT学会 , THE CHEMICAL SOCIETY OF JAPAN

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