Rchr
J-GLOBAL ID：201201099814158535
Update date: Oct. 19, 2024
Shirakawa Jun
シラカワ ジュン | Shirakawa Jun
Affiliation and department：
Homepage URL (1)：
https://diabetes.imcr.gunma-u.ac.jp/
Research field (5)：
Metabolism and endocrinology
, Nutrition and health science
, Pathobiochemistry
, Laboratory animal science
, Cell biology
Research keywords (6)：
pancreatic beta cell
, diabetes
, obesity
, human islets
, endocrinology
, database analysis
Research theme for competitive and other funds (7)：
- 2020 - 2023 Regulation of beta cell fate during dedifferentiation
- 2020 - 2023 Elucidation of pathogenesis and treatment of islet mitochondrial dysfunction and inflammation under glucolipotoxicity
- 2018 - 2021 A novel sarcopenia model by insulin / IGF-1 receptor inhibition
- 2018 - 2020 Heterogeneity of pancreatic islets
- 2016 - 2019 Fate determination of pancreatic beta cells by glucokinase activation
- 2013 - 2015 Glucokinase Activation Ameliorates ER Stress-Induced Apoptosis in Pancreatic Beta-Cells
- 2012 - 2015 Establishing a base for tailor-made therapy on diabetes from the view point of the pancreatic beta cell mass
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Papers (93)：
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Azeddine Tahiri, Ayman Youssef, Ryota Inoue, Sohyun Moon, Lamyaa Alsarkhi, Laila Berroug, Xuan Thi Anh Nguyen, Le Wang, Hyokjoon Kwon, Zhiping P Pang, et al. Vagal sensory neuron-derived FGF3 controls insulin secretion. Developmental cell. 2024
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Masahiko Honda, Ryota Inoue, Kuniyuki Nishiyama, Takeshi Ueda, Akiyoshi Komuro, Hisayuki Amano, Ryoichi Sugisawa, Suman Dash, Jun Shirakawa, Hitoshi Okada. Vgll2 as an integrative regulator of mitochondrial function and contractility specific to skeletal muscle. Journal of cellular physiology. 2024. e31436
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Junko Nishida, Takahiro Tsuno, Shigeharu G Yabe, Tatsuya Kin, Satsuki Fukuda, Fujie Takeda, Jun Shirakawa, Hitoshi Okochi. Encapsulated human islets in alginate fiber maintain long-term functionality. Endocrine journal. 2024. 71. 3. 253-264
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Sakiko Terui, Mari Igari, Takahiro Tsuno, Tomoko Okuyama, Ryota Inoue, Mayu Kyohara, Yasuo Terauchi, Jun Shirakawa. Immediate Impact of Switching from Dipeptidyl Peptidase 4 (DPP4) Inhibitors to Low-Dose (0.3 mg) Liraglutide on Glucose Profiles: A Retrospective Observational Study. Diabetes therapy : research, treatment and education of diabetes and related disorders. 2024
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Sohyun Moon, Lamyaa Alsarkhi, Tai-Tu Lin, Ryota Inoue, Azeddine Tahiri, Cecilia Colson, Weikang Cai, Jun Shirakawa, Wei-Jun Qian, Jerry Yingtao Zhao, et al. Transcriptome and secretome profiling of sensory neurons reveals sex differences in pathways relevant to insulin sensing and insulin secretion. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2023. 37. 10. e23185
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MISC (33)：
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Jun Shirakawa, Erin R. Okawa, Rohit N. Kulkarni. Characterization of Insulin-Like Growth Factor-2 Receptor (IGF-2R) in Pancreatic beta-Cells. DIABETES. 2017. 66. A12-A12
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Mayu Kyohara, Jun Shirakawa, Ayuko Kimura, Hisashi Hirano, Yasuo Terauchi. Identification of Soluble EGFR as a Serum Biomarker of Insulin Resistance by a Quantitative Proteomic Analysis Using Mice with Diabetes. DIABETES. 2017. 66. A542-A542
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Manoj K. Gupta, Heidrun Vethe, Vilas Wagh, Jun Shirakawa, Samir Softic, Harald Barsnes, Marc Vaudel, Tomozumi Takatani, Rachel Martinez, Jiang Hu, et al. Differential Regulation of Metabolic and Protein Synthesis Pathways in Mouse Embryonic Fibroblasts and Induced Pluripotent Stem Cells from Leptin Receptor Deficient Mice. DIABETES. 2016. 65. A504-A505
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Jun Shirakawa, Megan Fernandez, Rohit N. Kulkarni. Histone H3 Variant Centromere Protein A (CENP-A) Is Critical for beta-Cell Proliferation. DIABETES. 2016. 65. A17-A17
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Ivan A. Valdez, Ercument Dirice, Manoj K. Gupta, Jun Shirakawa, Adrian K. K. Teo, Rohit N. Kulkarni. Inflammatory Cytokines Activate NGN3 and Induce Pancreatic Ductal-to-Endocrine Cell Differentiation. DIABETES. 2016. 65. A531-A531
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Education (2)：
- - 2011 Yokohama City University Graduate School of Medicine
- - 2006 Tsukuba University School of Medicine
Professional career (2)：
- M.D.
- Ph.D. (University of Tsukuba)
Work history (8)：
- 2020 - 現在 Gunma University Institute for Molecular and Cellular Regulation, Laboratory of Diabetes and Metabolic Disorders Professor
- 2019 - 2020 Yokohama City University
- 2017 - 2019 Yokohama City University
- 2014 - 2017 Harvard Medical School Joslin Diabetes Center Research Fellow
- 2013 - 2014 Yokohama City University School of Medicine, Department of Endocrinology and Metabolism Assistant Professor
- 2011 - 2013 Yokohama City University Assistant Professor
- 2009 - 2011 JSPS fellow
- 2006 - 2008 Kanto Central Hpspital
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Awards (17)：
- 2022/10 - Asian Association for Study of Diabetes (AASD) The Masato Kasuga Award for Outstanding Scientific Achievement
- 2021/05 - JDS Lilly award
- 2020/05 - 横浜市立大学 医学会賞
- 2019/06 - 横浜市立大学医学部医学科 平成30年度ベストティーチャー賞 個人賞
- 2019/05 - 日本内分泌学会 研究奨励賞
- 2018/09 - Front Runner of Future Diabetes Research に関する研究助成(FFDR) 第7回研究発表会 最優秀賞
- 2018/02 - 第5回 東京未来医療フォーラム 優秀賞
- 2017/06 - American Diabetes Association's (ADA) American Diabetes Association's (ADA) 77nd Scientific Sessions Young Investigator Travel Grant Award
- 2014/05 - 横浜市立大学 医学研究奨励賞
- 2012/06 - American Diabetes Association's (ADA) 72nd Scientific Sessions Young Investigator Travel Grant Award
- 2012/05 - 日本糖尿病学会 若手研究奨励賞(YIA)
- 2012/04 - 日本内分泌学会 若手研究奨励賞(YIA)
- 2012/03 - 横浜市立大学大学院医学研究科 優秀論文賞
- 2011/12 - Advans研究会 Advans encourage award(AEA)優秀賞
- 2011/11 - 日本糖尿病・肥満動物学会 若手研究奨励賞(YIA)
- 2005/12 - JASSO's Student of the Year the grand prize
- 2005/03 - 筑波大学学長表彰
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Association Membership(s) (6)：
JAPANESE SOCIETY OF EXPERIMENTAL DIABETES AND OBESITY (JSEDO)
, THE JANPANESE SOCIETY OF INTERNAL MEDICINE
, THE JAPAN ENDOCRINE SOCIETY
, JAPAN DIABETES SOCIETY
, アジア糖尿病学会(AASD)
, 日本生化学会
