Art

J-GLOBAL ID：201202202327059342   Reference number：12A1524209

Ternatin, a cyclic peptide isolated from mushroom, and its derivative suppress hyperglycemia and hepatic fatty acid synthesis in spontaneously diabetic KK-A^y mice

キノコから単離されたシクロペプチド テルナチンとその誘導体は自然発症糖尿病KK-A^yマウスにおいて高血糖と肝臓脂肪酸合成を抑制する

Author (9)： KOBAYASHI Misato (Dep. of Applied Biosciences, Graduate School of Bioagricultural Sciences, Nagoya Univ., Nagoya 464-8601, JPN) ,  KAWASHIMA Haruna (Dep. of Applied Biosciences, Graduate School of Bioagricultural Sciences, Nagoya Univ., Nagoya 464-8601, JPN) ,  TAKEMORI Kumiko (Dep. of Food and Nutrition, Kinki Univ. Fac. of Agriculture, Nara 631-8505, JPN) ,  ITO Hiroyuki (Dep. of Biomedical Engineering, Kinki Univ. Fac. of Biology-Oriented Engineering, Wakayama 649-6493, JPN) ,  MURAI Atsushi (Dep. of Applied Biosciences, Graduate School of Bioagricultural Sciences, Nagoya Univ., Nagoya 464-8601, JPN) ,  MASUDA Shun (Dep. of Chemistry, Kanagawa Univ., Kanagawa 259-1293, JPN) ,  YAMADA Kaoru (Dep. of Chemistry, Kanagawa Univ., Kanagawa 259-1293, JPN) ,  UEMURA Daisuke (Dep. of Chemistry, Kanagawa Univ., Kanagawa 259-1293, JPN) ,  HORIO Fumihiko (Dep. of Applied Biosciences, Graduate School of Bioagricultural Sciences, Nagoya Univ., Nagoya 464-8601, JPN)
Material： Biochemical and Biophysical Research Communications  (BBRC)
Volume： 427  Issue： 2  Page： 299-304  Publication year： Oct. 19, 2012 
JST Material Number： B0118A  ISSN： 0006-291X  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Thesaurus term： *hyperglycemia ,  *cyclopeptide ,  mouse(animal) ,  *lipid metabolism ,  laboratory animal ,  experimental disease ,  Coriolus ,  tumor cell ,  cultured cell ,  transcription factor ,  gene expression ,  *type 2 diabetes mellitus
Semi thesaurus term： *non-insulin-dependent diabetes mellitus ,  fatty acid synthesis ,  KKAy mouse ,  Coriolus versicolor ,  Hepa1-6 cell ,  SREBP1c

JST classification (4)： Metabolic diseases,nutritional diseases in general.  (GD05010J) ,  Biological function  (EB03040U) ,  Microorganism biochemistry  (EG03020N) ,  Basic research of drugs acting on carbohydrate metabolism  (GW13020Q)

Substance index (1)： Ternatin

Terms in the title (11)： キノコ ,  単離 ,  シクロペプチド ,  テルナチン ,  誘導体 ,  自然発症 ,  糖尿病 ,  KK-Ayマウス ,  高血糖 ,  肝臓 ,  脂肪酸合成