Art

J-GLOBAL ID：201202209943461973   Reference number：12A0192357

突然変異抑制酵素NUDT5の幅広い基質特異性発現機構

Author (2)： ARIMORI TAKAO (日本原子力研究開発機構) ,  YAMAGATA YURIKO (熊本大 大学院生命科学研究部)
Material： 福岡医学雑誌  (Fukuoka Acta Medica)
Volume： 102  Issue： 11  Page： 303-312  Publication year： Nov. 25, 2011 
JST Material Number： F0687A  ISSN： 0016-254X  CODEN： FKIZA4  Document type： Article
Article type： 解説  Country of issue： Japan (JPN)  Language： JAPANESE (JA)

Thesaurus term： human ,...
Semi thesaurus term： *NUDT5

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JST classification (1)： Enzyme in general  (EB09010D)

Substance index (1)： ADP ribose

Reference (29)：

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• 2) Moriya M, Ou C, Bodepudi V, Johnson F, Takeshita M and Grollman AP : Site-specific mutagenesis using a gapped duplex vector : a study of translesion synthesis past 8-oxodeoxyguanosine in E. coli.Mutat.Res.254 : 281-288, 1991.
• 3) Shibutani S, Takeshita M and Grollman A : Insertion of specific bases during DNA synthesis past the oxidation-damaged base 8-oxodG. Nature 349 : 431-434, 1991.
• 4) Markesbery W and Carney J : Oxidative alterations in Alzheimer's disease. Brain Pathol. 9 : 133-146, 1999.
• 5) Ohtsubo T, Ohya Y, Nakamura Y, Kansui Y, Furuichi M, Matsumura K, Fujii K,Iida M and Nakabeppu Y : Accumulation of 8-oxo-deoxyguanosine in cardiovascular tissues with the development of hypertension. DNA Repair (Amst) 6 : 760-769, 2007.

Terms in the title (4)： 突然変異 ,  酵素 ,  NUDT5 ,  基質特異性