Art

J-GLOBAL ID：201202211474505292   Reference number：12A0110538

The C-terminal domain of the adenomatous polyposis coli (Apc) protein is involved in thyroid morphogenesis and function

大腸腺腫様ポリポーシス(Apc)タンパク質のC末端ドメインは甲状腺の形態形成と機能に関与する

Author (11)： YOKOYAMA Atsushi (Fujita Health Univ. School of Medicine, Aichi, JPN) ,  NOMURA Ryuji (Fujita Health Univ. School of Medicine, Aichi, JPN) ,  KUROSUMI Masafumi (Saitama Cancer Center, Saitama, JPN) ,  SHIMOMURA Atsushi (Fujita Health Univ. School of Medicine, Aichi, JPN) ,  ONOUCHI Takanori (Fujita Health Univ. School of Medicine, Aichi, JPN) ,  IIZUKA-KOGO Akiko (Fujita Health Univ. School of Medicine, Aichi, JPN) ,  SMITS Ron (Erasmus Medical Center, Rotterdam, NLD) ,  ODA Naohisa (Fujita Health Univ. School of Medicine, Aichi, JPN) ,  FODDE Riccardo (Erasmus Medical Center, Rotterdam, NLD) ,  ITOH Mitsuyasu (Fujita Health Univ. School of Medicine, Aichi, JPN) ,  SENDA Takao (Fujita Health Univ. School of Medicine, Aichi, JPN)
Material： Medical Molecular Morphology  (Med Mol Morphol)
Volume： 44  Issue： 4  Page： 207-212  Publication year： Dec. 2011 
JST Material Number： L1883A  ISSN： 1860-1480  Document type： Article
Article type： 解説  Country of issue： Germany, Federal Republic of (DEU)  Language： ENGLISH (EN)

Thesaurus term： mouse(animal) ,...
Semi thesaurus term： *APC protein ,...

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JST classification (2)： Basic medicine on endocrine system  (GL01020Q) ,  Biological function  (EB03040U)

Substance index (2)： Triiodothyronine ,  Thyroxin

Reference (23)：

• GRODEN, J. Identification and characterization of the familial adenomatous polyposis coli gene. Cell. 1991, 66, 589-600
• KINZLER, KW. Identification of FAP locus genes from chromosome 5q21. Science. 1991, 253, 661-665
• NISHISHO, I. Mutations of chromosome 5q21 genes in FAP and colorectal cancer patients. Science. 1991, 253, 665-669
• POWELL, SM. APC mutations occur early during colorectal tumorigenesis. Nature (Lond). 1992, 359, 235-237
• HALF, E. Familial adenomatous polyposis. Orphanet J Rare Dis. 2009, 4, 22

Terms in the title (7)： 大腸腺腫 ,  ポリポーシス ,  APC ,  タンパク質 ,  C末端ドメイン ,  甲状腺 ,  形態形成