Art

J-GLOBAL ID：201202211723915951   Reference number：12A0170801

Mixed Lineage Kinase Domain-like Protein Mediates Necrosis Signaling Downstream of RIP3 Kinase

混合系統キナーゼ領域様蛋白質はRIP3キナーゼのネクローシスシグナル伝達下流を媒介する

Author (17)： SUN Liming (National Inst. of Biological Sciences, 7 Sci. Park Road, Zhongguancun Life Sci. Park, Beijing 102206, CHN) ,  SUN Liming (Dep. of Biochemistry, Univ. of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390, USA) ,  WANG Huayi (National Inst. of Biological Sciences, 7 Sci. Park Road, Zhongguancun Life Sci. Park, Beijing 102206, CHN) ,  WANG Huayi (Dep. of Biochemistry, Univ. of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390, USA) ,  WANG Zhigao (Dep. of Biochemistry, Univ. of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390, USA) ,  HE Sudan (National Inst. of Biological Sciences, 7 Sci. Park Road, Zhongguancun Life Sci. Park, Beijing 102206, CHN) ,  CHEN She (National Inst. of Biological Sciences, 7 Sci. Park Road, Zhongguancun Life Sci. Park, Beijing 102206, CHN) ,  LIAO Daohong (National Inst. of Biological Sciences, 7 Sci. Park Road, Zhongguancun Life Sci. Park, Beijing 102206, CHN) ,  LIAO Daohong (School of Pharmaceutical Sci. and Technol., Tianjin Univ., Tianjin 300072, CHN) ,  WANG Lai (Dep. of Biochemistry, Univ. of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390, USA) ,  YAN Jiacong (National Inst. of Biological Sciences, 7 Sci. Park Road, Zhongguancun Life Sci. Park, Beijing 102206, CHN) ,  LIU Weilong (National Inst. of Biological Sciences, 7 Sci. Park Road, Zhongguancun Life Sci. Park, Beijing 102206, CHN) ,  LIU Weilong (Peking Union Medical Coll. and Chinese Acad. of Medical Sciences, Beijing 100730, CHN) ,  LEI Xiaoguang (National Inst. of Biological Sciences, 7 Sci. Park Road, Zhongguancun Life Sci. Park, Beijing 102206, CHN) ,  LEI Xiaoguang (School of Pharmaceutical Sci. and Technol., Tianjin Univ., Tianjin 300072, CHN) ,  WANG Xiaodong (National Inst. of Biological Sciences, 7 Sci. Park Road, Zhongguancun Life Sci. Park, Beijing 102206, CHN) ,  WANG Xiaodong (Dep. of Biochemistry, Univ. of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390, USA)
Material： Cell (Cambridge, Mass.)  (Cell (Camb. Mass.))
Volume： 148  Issue： 1-2  Page： 213-227  Publication year： Jan. 20, 2012 
JST Material Number： A0707B  ISSN： 0092-8674  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Thesaurus term： *serine-threonine kinase ,  Proteins ,  *Cell Death ,  phosphorylation ,  sulfur-containing polymer ,  protein kinase ,  gene targetting ,  tumor cell ,  cultured cell ,  Jurkat cell ,  HeLa cell ,  amino acid residue ,  HT 29 Cells ,  Signal Transduction ,  *RIPK3 ,  *Necrosis ,  Gene Knockdown Technique
Semi thesaurus term： cellular signal transduction ,  *RIP3 ,  *necrotic cell death ,  gene knockdown ,  混合系統キナーゼ領域様蛋白質

JST classification (2)： Biological function  (EB03040U) ,  Cell physiology in general  (EF02010S)

Substance index (1)： Necrosulfonamide

Terms in the title (7)： 系統 ,  キナーゼ ,  蛋白質 ,  RIP3 ,  ネクローシス ,  シグナル伝達 ,  下流