Redesign of coenzyme B<sub>12</sub> dependent diol dehydratase to be resistant to the mechanism-based inactivation by glycerol and act on longer chain 1,2-diols

YAMANISHI Mamoru; KINOSHITA Koichiro; FUKUOKA Masaki; SAITO Takuya; TANOKUCHI Aya; IKEDA Yuuki; OBAYASHI Hirokazu; MORI Koichi; SHIBATA Naoki; SHIBATA Naoki; TOBIMATSU Takamasa; TORAYA Tetsuo

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J-GLOBAL ID：201202214455740751 Reference number：12A0528022

Redesign of coenzyme B₁₂ dependent diol dehydratase to be resistant to the mechanism-based inactivation by glycerol and act on longer chain 1,2-diols

グリセロールによる機序に基づく不活化に抵抗してより長鎖の1,2-ジオールに作用する補酵素B₁₂依存的ジオールデヒドラターゼの再設計

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Material：
Volume： 279 Issue： 5 Page： 793-804 Publication year： Mar. 2012
JST Material Number： B0206B ISSN： 1742-464X Document type： Article
Article type：原著論文 Country of issue： United States (USA) Language： ENGLISH (EN)

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Molecular structure , Enzyme in general

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Redesign of coenzyme B12 dependent diol dehydratase to be resistant to the mechanism-based inactivation by glycerol and act on longer chain 1,2-diols

Redesign of coenzyme B₁₂ dependent diol dehydratase to be resistant to the mechanism-based inactivation by glycerol and act on longer chain 1,2-diols