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J-GLOBAL ID：201202217383829310   Reference number：12A0548710

血栓症に関するQ&A PART 6 8.薬剤 Q57 プロスタサイクリンと血管再生について教えてください

Author (1)： KAWABE JUN'ICHI (旭川医大 心血管再生先端医療開発)
Material： 血栓と循環  (Thrombosis and Circulation)
Volume： 19  Issue： 1  Page： 189-191  Publication year： Mar. 25, 2011 
JST Material Number： L2732A  ISSN： 0919-7036  Document type： Article
Article type： 解説  Country of issue： Japan (JPN)  Language： JAPANESE (JA)

Thesaurus term： *angiogenesis ,...

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JST classification (2)： Basic medicine on cardiovascular system  (GJ01020K) ,  Other hormones of verterbrates  (EB08070K)

Substance index (1)： Epoprostenol

Reference (11)：

• 1) Kawabe J, Ushikubi F, Hasebe N : Prostacyclin in vascular diseases-Recent insights and future perspec-tives-. Circulation J 74 : 836-843, 2010
• 2) Cheng Y, Austin SC, Rocca B, et al : Role of Prostacyclin in the car-diovascular response to thrombox-ane A2. Science 296 : 539-541, 2002
• 3) Numaguchi Y, Naruse K, Harada M, et al : Prostacyclin synthase gene transfer accelerates reendothelial-ization and inhibits neiointimal for-mation in rat carotid arteries after balloon injury. Arterioscler Thromb Vasc Biol 19 : 727-733,1999
• 4) Hiraoka K, Koike H, Yamamoto S, et al : Enhanced therapeutic angio-genesis by cotransfection of prosta-cyclin synthase gene or optimiza-tion of intramuscular injection of naked plasmid DNA. Circulation 108 : 2689-2696,2003
• 5) Niwano K, Arai M, Tomaru K, et al : Transcriptional stimulation of the eNOS gene by the stable pros-tacyclin analogue beraprost is me-diated through cAMP-responsive element in vascular endothelial cells. Crose link between PGI2 sig- nal and NO pathways. Circ Res 93 : 523-530,2003

Terms in the title (4)： 血栓症 ,  薬剤 ,  プロスタサイクリン ,  血管再生