Art

J-GLOBAL ID：201202218647288629   Reference number：12A1581933

Demonstrated brain insulin resistance in Alzheimer’s disease patients is associated with IGF-1 resistance, IRS-1 dysregulation, and cognitive decline

アルツハイマー病患者において示された脳のインスリン抵抗性はIGF-1抵抗性,IRS-1の調節不全,および認知機能低下に関連する

Author (17)： TALBOT Konrad (Univ. of Pennsylvania, Pennsylvania, USA) ,  WANG Hoau-Yan (City Univ. of New York Medical School, New York, USA) ,  KAZI Hala (Univ. of Pennsylvania, Pennsylvania, USA) ,  HAN Li-Ying (Univ. of Pennsylvania, Pennsylvania, USA) ,  BAKSHI Kalindi P. (City Univ. of New York Medical School, New York, USA) ,  STUCKY Andres (City Univ. of New York Medical School, New York, USA) ,  FUINO Robert L. (Univ. of Pennsylvania, Pennsylvania, USA) ,  KAWAGUCHI Krista R. (Univ. of Pennsylvania, Pennsylvania, USA) ,  SAMOYEDNY Andrew J. (Univ. of Pennsylvania, Pennsylvania, USA) ,  WILSON Robert S. (Rush Univ. Medical Center, Illinois, USA) ,  ARVANITAKIS Zoe (Rush Univ. Medical Center, Illinois, USA) ,  SCHNEIDER Julie A. (Rush Univ. Medical Center, Illinois, USA) ,  WOLF Bryan A. (Univ. of Pennsylvania, Pennsylvania, USA) ,  WOLF Bryan A. (Children’s Hospital of Philadelphia, Pennsylvania, USA) ,  BENNETT David A. (Rush Univ. Medical Center, Illinois, USA) ,  TROJANOWSKI John Q. (Univ. of Pennsylvania, Pennsylvania, USA) ,  ARNOLD Steven E. (Univ. of Pennsylvania, Pennsylvania, USA)
Material： Journal of Clinical Investigation  (JCI)
Volume： 122  Issue： 4  Page： 1316-1338  Publication year： Apr. 2012 
JST Material Number： B0520B  ISSN： 0021-9738  Document type： Article
Country of issue： United States (USA)  Language： ENGLISH (EN)

Terms in the title (8)： アルツハイマー病 ,  患者 ,  脳 ,  インスリン抵抗性 ,  IGF-1 ,  抵抗性 ,  調節 ,  認知機能低下