Art

J-GLOBAL ID：201202222030972821   Reference number：12A0164347

Formation of repressor-inducer-operator ternary complex: negative cooperativity of D-camphor binding to CamR

レプレッサー-インデューサ-オペレータ三成分複合体の形成 CamRに結合するd-カンフルの負の協同作用

Author (6)： ARAMAKI Hironori (Daiichi Univ. Pharmacy, Fukuoka, JPN) ,  KABATA Hiroyuki (National Inst. Genetics, Shizuoka, JPN) ,  TAKEDA Shuso (Daiichi Univ. Pharmacy, Fukuoka, JPN) ,  ITOU Hiroshi (National Inst. Genetics, Shizuoka, JPN) ,  NAKAYAMA Hideki (National Inst. Genetics, Shizuoka, JPN) ,  SHIMAMOTO Nobuo (National Inst. Genetics, Shizuoka, JPN)
Material： Genes to Cells  (Genes Cells)
Volume： 16  Issue： 12  Page： 1200-1207  Publication year： Dec. 2011 
JST Material Number： W0935A  ISSN： 1356-9597  CODEN： GECEFL  Document type： Article
Article type： 原著論文  Country of issue： Australia (AUS)  Language： ENGLISH (EN)

Thesaurus term： *repressor ,...
Semi thesaurus term： *camレプレッサー ,...

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JST classification (3)： Enzyme physiology  (EG03052C) ,  Gene expression  (EC02040Q) ,  Proteins and peptides in general  (EB03010N)

Substance index (1)： (+)-Camphor

Reference (28)：

• Algue, Y., Meng, C., Terán, W., Krell, T., Ramos, J.L., Gallegos, M.T. & Zhang, X. (2007) Crystal structures of multidrug binding protein TtgR in complex with antibiotics and plant antimicrobials. J. Mol. Biol. 369, 829-840.
• Aramaki, H., Sagara, Y., Hosoi, M. & Horiuchi, T. (1993) Evidence for autoregulation of camR, which encodes a repressor for the cytochrome P-450cam hydroxylase operon on the Pseudomonas putida CAM plasmid. J. Bacteriol. 175, 7828-7833.
• Aramaki, H., Sagara, Y., Kabata, H., Shimamoto, N. & Horiuchi, T. (1995a) Purification and characterization of a cam repressor (CamR) for the cytochrome P-450cam hydroxylase operon on the Pseudomonas putida CAM plasmid. J. Bacteriol. 177, 3120-3127.
• Aramaki, H., Sagara, Y., Takeuchi, K., Koga, H. & Horiuchi, T. (1994) Nucleotide sequence of the gene encoding a repressor for the cytochrome P-450cam hydroxylase operon on the Pseudomonas putida CAM plasmid. Biochimie 76, 63-70.
• Aramaki, H., Yagi, N. & Suzuki, M. (1995b) Residues important for the function of a multihelical DNA binding domain in the new transcription factor family of Cam and Tet repressors. Protein Eng. 91, 1259-1266.

Terms in the title (5)： レプレッサー ,  インデューサ ,  オペレータ ,  複合体 ,  d-カンフル