Novel monoclonal antibody recognizing triglyceride-rich oxidized LDLs associated with severe liver disease and small oxidized LDLs in normal subjects

SAKURAI Toshihiro; ICHIKAWA Ayako; ICHIKAWA Ayako; FURUKAWA Hiroyuki; WADA Norio; NAGASAKA Atsushi; TAKAHASHI Yuji; TAKAHASHI Yuji; FUJIKAWA Masato; IKUTA Akiko; FURUMAKI Hiroaki; SHIGA Maiko; SHIMIZU Chikara; HUI Shu-Ping; JIN Shigeki; TAKEDA Seiji; FUDA Hirotoshi; NAGASAKA Hironori; KOBAYASHI Seiichi; CHIBA Hitoshi

Art

J-GLOBAL ID：201202223711592616 Reference number：12A1585236

Novel monoclonal antibody recognizing triglyceride-rich oxidized LDLs associated with severe liver disease and small oxidized LDLs in normal subjects

重度肝疾患と関係したトリグリセリドリッチ酸化LDLsを認識する新しいモノクローナル抗体および正常なヒトでの小酸化LDLs

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Material：
Volume： 49 Issue： 5 Page： 456-462 Publication year： Sep. 2012
JST Material Number： B0921B ISSN： 0004-5632 Document type： Article
Article type：原著論文 Country of issue： United Kingdom (GBR) Language： ENGLISH (EN)

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Biological function , Basic medicine on digestive system

Reference (40)：

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Steinberg D, Pittman RC, Carew TE. Mechanisms involved in the uptake and degradation of low density lipoprotein by artery wall in vivo. Ann NY Acad Sci 1985;454:195-206
Itabe H, Takeshima E, Iwasaki H, et al. A monoclonal antibody against oxidized lipoprotein recognizes form cells in atherosclerotic lesions. J Biol Chem 1994;269:15274-9
Holvoet P, Mertens A, Verhamme P, et al. Circulating oxidized LDL is a useful marker for identifying patients with coronary artery disease. Arterioscler Thromb Vasc Biol 2001;21:844-8
Ehara S, Ueda M, Naruko T, et al. Elevated levels of oxidized low density lipoprotein show a positive relationship with the severity of acute coronary syndromes. Circulation 2001;103:1955-60

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