Art

J-GLOBAL ID：201202223711592616   Reference number：12A1585236

Novel monoclonal antibody recognizing triglyceride-rich oxidized LDLs associated with severe liver disease and small oxidized LDLs in normal subjects

重度肝疾患と関係したトリグリセリドリッチ酸化LDLsを認識する新しいモノクローナル抗体および正常なヒトでの小酸化LDLs

Author (20)： SAKURAI Toshihiro (Hokkaido Univ., Sapporo) ,  ICHIKAWA Ayako (Hokkaido Univ., Sapporo) ,  ICHIKAWA Ayako (Hokkaido Univ. Hospital, Sapporo) ,  FURUKAWA Hiroyuki (Hokkaido Univ. Graduate School of Medicine, Sapporo) ,  WADA Norio (Sapporo City General Hospital, Sapporo) ,  NAGASAKA Atsushi (Sapporo City General Hospital, Sapporo) ,  TAKAHASHI Yuji (Hokkaido Univ., Sapporo) ,  TAKAHASHI Yuji (Sapporo City General Hospital, Sapporo) ,  FUJIKAWA Masato (Sapporo City General Hospital, Sapporo) ,  IKUTA Akiko (Hokkaido Univ., Sapporo) ,  FURUMAKI Hiroaki (Hokkaido Univ., Sapporo) ,  SHIGA Maiko (Hokkaido Univ. Hospital, Sapporo) ,  SHIMIZU Chikara (Hokkaido Univ. Hospital, Sapporo) ,  HUI Shu-Ping (Hokkaido Univ., Sapporo) ,  JIN Shigeki (Hokkaido Univ., Sapporo) ,  TAKEDA Seiji (Hokkaido Univ., Sapporo) ,  FUDA Hirotoshi (Hokkaido Univ., Sapporo) ,  NAGASAKA Hironori (Takarazuka City Hospital, Takarazuka, JPN) ,  KOBAYASHI Seiichi (Hokkaido Univ., Sapporo) ,  CHIBA Hitoshi (Hokkaido Univ., Sapporo)
Material： Annals of Clinical Biochemistry  (Ann Clin Biochem)
Volume： 49  Issue： 5  Page： 456-462  Publication year： Sep. 2012 
JST Material Number： B0921B  ISSN： 0004-5632  Document type： Article
Article type： 原著論文  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Thesaurus term： *liver disease ,...
Semi thesaurus term： Sandwich immunoassay ,...

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JST classification (2)： Biological function  (EB05020M) ,  Basic medicine on digestive system  (GH01020E)

Reference (40)：

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• Steinberg D, Pittman RC, Carew TE. Mechanisms involved in the uptake and degradation of low density lipoprotein by artery wall in vivo. Ann NY Acad Sci 1985;454:195-206
• Itabe H, Takeshima E, Iwasaki H, et al. A monoclonal antibody against oxidized lipoprotein recognizes form cells in atherosclerotic lesions. J Biol Chem 1994;269:15274-9
• Holvoet P, Mertens A, Verhamme P, et al. Circulating oxidized LDL is a useful marker for identifying patients with coronary artery disease. Arterioscler Thromb Vasc Biol 2001;21:844-8
• Ehara S, Ueda M, Naruko T, et al. Elevated levels of oxidized low density lipoprotein show a positive relationship with the severity of acute coronary syndromes. Circulation 2001;103:1955-60

Terms in the title (3)： 肝疾患 ,  モノクローナル抗体 ,  ヒト