Art

J-GLOBAL ID：201202225050714054   Reference number：12A0927121

The design, synthesis, and biological evaluation of PIM kinase inhibitors

PIMキナーゼ阻害剤の設計、合成および生物学的評価

Author (28)： TSUHAKO Amy Lew (Exelixis, Dep. of Drug Discovery, 210 East Grand, South San Francisco, CA 94080, USA) ,  BROWN David S. (Exelixis, Dep. of Drug Discovery, 210 East Grand, South San Francisco, CA 94080, USA) ,  KOLTUN Elena S. (Exelixis, Dep. of Drug Discovery, 210 East Grand, South San Francisco, CA 94080, USA) ,  AAY Naing (Exelixis, Dep. of Drug Discovery, 210 East Grand, South San Francisco, CA 94080, USA) ,  ARCALAS Arlyn (Exelixis, Dep. of Drug Discovery, 210 East Grand, South San Francisco, CA 94080, USA) ,  CHAN Vicky (Exelixis, Dep. of Drug Discovery, 210 East Grand, South San Francisco, CA 94080, USA) ,  DU Hongwang (Exelixis, Dep. of Drug Discovery, 210 East Grand, South San Francisco, CA 94080, USA) ,  ENGST Stefan (Exelixis, Dep. of Drug Discovery, 210 East Grand, South San Francisco, CA 94080, USA) ,  FRANZINI Maurizio (Exelixis, Dep. of Drug Discovery, 210 East Grand, South San Francisco, CA 94080, USA) ,  GALAN Adam (Exelixis, Dep. of Drug Discovery, 210 East Grand, South San Francisco, CA 94080, USA) ,  HUANG Ping (Exelixis, Dep. of Drug Discovery, 210 East Grand, South San Francisco, CA 94080, USA) ,  JOHNSTON Stuart (Exelixis, Dep. of Drug Discovery, 210 East Grand, South San Francisco, CA 94080, USA) ,  KANE Brian (Exelixis, Dep. of Drug Discovery, 210 East Grand, South San Francisco, CA 94080, USA) ,  KIM Moon H. (Exelixis, Dep. of Drug Discovery, 210 East Grand, South San Francisco, CA 94080, USA) ,  DOUGLAS LAIRD A. (Exelixis, Dep. of Drug Discovery, 210 East Grand, South San Francisco, CA 94080, USA) ,  LIN Rui (Exelixis, Dep. of Drug Discovery, 210 East Grand, South San Francisco, CA 94080, USA) ,  MOCK Lillian (Exelixis, Dep. of Drug Discovery, 210 East Grand, South San Francisco, CA 94080, USA) ,  NGAN Iris (Exelixis, Dep. of Drug Discovery, 210 East Grand, South San Francisco, CA 94080, USA) ,  PACK Michael (Exelixis, Dep. of Drug Discovery, 210 East Grand, South San Francisco, CA 94080, USA) ,  STOTT Gordon (Exelixis, Dep. of Drug Discovery, 210 East Grand, South San Francisco, CA 94080, USA) ,  STOUT Thomas J. (Exelixis, Dep. of Drug Discovery, 210 East Grand, South San Francisco, CA 94080, USA) ,  YU Peiwen (Exelixis, Dep. of Drug Discovery, 210 East Grand, South San Francisco, CA 94080, USA) ,  ZAHARIA Cristiana (Exelixis, Dep. of Drug Discovery, 210 East Grand, South San Francisco, CA 94080, USA) ,  ZHANG Wentao (Exelixis, Dep. of Drug Discovery, 210 East Grand, South San Francisco, CA 94080, USA) ,  ZHOU Peiwen (Exelixis, Dep. of Drug Discovery, 210 East Grand, South San Francisco, CA 94080, USA) ,  NUSS John M. (Exelixis, Dep. of Drug Discovery, 210 East Grand, South San Francisco, CA 94080, USA) ,  KEARNEY Patrick C. (Exelixis, Dep. of Drug Discovery, 210 East Grand, South San Francisco, CA 94080, USA) ,  XU Wei (Exelixis, Dep. of Drug Discovery, 210 East Grand, South San Francisco, CA 94080, USA)
Material： Bioorganic & Medicinal Chemistry Letters  (Bioorg Med Chem Lett)
Volume： 22  Issue： 11  Page： 3732-3738  Publication year： Jun. 01, 2012 
JST Material Number： W0248A  ISSN： 0960-894X  Document type： Article
Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Terms in the title (4)： PIM ,  キナーゼ阻害剤 ,  設計 ,  生物学的評価