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J-GLOBAL ID：201202226736692711   Reference number：12A0419334

TDP43の発現抑制による細胞内小器官の形態変化

Author (1)： ARIIZUMI YUKO (新潟大 大学院医歯学総合研究科 神経内科学分野)
Material： 新潟医学会雑誌  (Niigata Medical Journal)
Volume： 125  Issue： 9  Page： 482-497  Publication year： Sep. 10, 2011 
JST Material Number： F0877A  ISSN： 0029-0440  CODEN： NIGZAY  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： JAPANESE (JA)

Thesaurus term： *Amyotrophic Lateral Sclerosis ,...
Semi thesaurus term： pathophysiological analysis

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JST classification (2)： Basic neurology  (GN01020W) ,  Cell components in general  (EF03010Z)

Reference (49)：

• 1) Neumann M, Sampathu DM, Kwong LK, Truax AC, Micsenyi MC, Chou TT, Bruce J, Schuck T, Grossman M, Clark CM, McCluskey LF, Miller BL, Masliah E, Mackenzie IR, Feldman H, Feiden W, Kretzschmar HA, Trojanowski JQ and Lee VM - Y: Ubiquitinated TDP - 43 in frontotempo - ral lobar degeneration and amyotrophic lateral scle - rosis. Science (New York, N.Y.) 314: 130 -133, 2006.
• 2) Arai T, Hasegawa M, Akiyama H, Ikeda K, Nonaka T, Mori H, Mann D, Tsuchiya K, Yoshida M, Hashizume Y and Oda T: TDP - 43 is a compo-nent of ubiquitin - positive tau - negativeinclu - sions in frontotemporal lobar degeneration and amyotrophic lateral sclerosis. Biochemical and biophysical research communications 351: 602 - 611, 2006.
• 3) Kabashi E, Valdmanis PN, Dion P, Spiegelman D, McConkey BJ, Vande Velde C, Bouchard J - P, Lacomblelz L, Pochigaeva K, Salachas F, Pradat P - F, Camu W, Meininger V, Dupre N and Rouleau GA: TARDBP mutations in individuals with sporadic and familial amyotrophic lateral sclerosis. Nature genetics 40: 572 - 574, 2008.
• 4) Sreedharan J, Blair IP, Tripathi VB, Hu X, Vance C, Rogelj B, Ackerley S, Duman JC, Milliams KL, Buratti E, Baralle F, Belleroche J, Mitchell JD, Leigh PN, Al - Chalabi A, Miller CC, Nicholson G and Shaw CE: TDP - 43 mutations in familial and sporadic amyotrophic lateral sclerosis. Science (New York, N.Y.) 319: 1668 -1672, 2008.
• 5) Gitcho MA, Baloh RH, Chakraverty 5, Mayo K, Norton JB, Levitch D, Hatanpaa KJ, White CL, Bigio EH, Caselli R, Baker M, Al - Lozi MT, Morris JC, Pestronk A, Rademakers R, Goate AM and Cairns NJ: TDP - 43 A315T mutation in famil - ial motor neuron disease. Annals of neurology 63: 535 - 538 2008.

Terms in the title (3)： TDP43 ,  発現抑制 ,  細胞内小器官