Art

J-GLOBAL ID：201202228322538403   Reference number：12A0802342

Melanoma genome sequencing reveals frequent PREX2 mutations

黒色腫ゲノムの塩基配列解読によって明らかになった頻発性のPREX2変異

Author (40)： BERGER Michael F. (Broad Inst. of Harvard and MIT, Massachusetts, USA) ,  HODIS Eran (Broad Inst. of Harvard and MIT, Massachusetts, USA) ,  LAWRENCE Michael S. (Broad Inst. of Harvard and MIT, Massachusetts, USA) ,  NICKERSON Elizabeth (Broad Inst. of Harvard and MIT, Massachusetts, USA) ,  CIBULSKIS Kristian (Broad Inst. of Harvard and MIT, Massachusetts, USA) ,  SIVACHENKO Andrey Y. (Broad Inst. of Harvard and MIT, Massachusetts, USA) ,  SOUGNEZ Carrie (Broad Inst. of Harvard and MIT, Massachusetts, USA) ,  ONOFRIO Robert (Broad Inst. of Harvard and MIT, Massachusetts, USA) ,  AMBROGIO Lauren (Broad Inst. of Harvard and MIT, Massachusetts, USA) ,  AUCLAIR Daniel (Broad Inst. of Harvard and MIT, Massachusetts, USA) ,  FENNELL Timothy (Broad Inst. of Harvard and MIT, Massachusetts, USA) ,  CARTER Scott L. (Broad Inst. of Harvard and MIT, Massachusetts, USA) ,  STOJANOV Petar (Broad Inst. of Harvard and MIT, Massachusetts, USA) ,  VOET Douglas (Broad Inst. of Harvard and MIT, Massachusetts, USA) ,  JING Rui (Broad Inst. of Harvard and MIT, Massachusetts, USA) ,  SAKSENA Gordon (Broad Inst. of Harvard and MIT, Massachusetts, USA) ,  BARRETINA Jordi (Broad Inst. of Harvard and MIT, Massachusetts, USA) ,  RAMOS Alex H. (Broad Inst. of Harvard and MIT, Massachusetts, USA) ,  PUGH Trevor J. (Broad Inst. of Harvard and MIT, Massachusetts, USA) ,  STRANSKY Nicolas (Broad Inst. of Harvard and MIT, Massachusetts, USA) ,  PARKIN Melissa (Broad Inst. of Harvard and MIT, Massachusetts, USA) ,  WINCKLER Wendy (Broad Inst. of Harvard and MIT, Massachusetts, USA) ,  MAHAN Scott (Broad Inst. of Harvard and MIT, Massachusetts, USA) ,  ARDLIE Kristin (Broad Inst. of Harvard and MIT, Massachusetts, USA) ,  BALDWIN Jennifer (Broad Inst. of Harvard and MIT, Massachusetts, USA) ,  MEYERSON Matthew (Broad Inst. of Harvard and MIT, Massachusetts, USA) ,  GABRIEL Stacey B. (Broad Inst. of Harvard and MIT, Massachusetts, USA) ,  GOLUB Todd R. (Broad Inst. of Harvard and MIT, Massachusetts, USA) ,  LANDER Eric S. (Broad Inst. of Harvard and MIT, Massachusetts, USA) ,  GETZ Gad (Broad Inst. of Harvard and MIT, Massachusetts, USA) ,  CHIN Lynda (Broad Inst. of Harvard and MIT, Massachusetts, USA) ,  GARRAWAY Levi A. (Broad Inst. of Harvard and MIT, Massachusetts, USA) ,  HEFFERNAN Timothy P. (Dana-Farber Cancer Inst., Massachusetts, USA) ,  DERIBE Yonathan Lissanu (Dana-Farber Cancer Inst., Massachusetts, USA) ,  PROTOPOPOV Alexei (Dana-Farber Cancer Inst., Massachusetts, USA) ,  IVANOVA Elena (Dana-Farber Cancer Inst., Massachusetts, USA) ,  WATSON Ian R. (Dana-Farber Cancer Inst., Massachusetts, USA) ,  GHOSH Papia (Dana-Farber Cancer Inst., Massachusetts, USA) ,  ZHANG Hailei (Dana-Farber Cancer Inst., Massachusetts, USA) ,  ZEID Rhamy (Dana-Farber Cancer Inst., Massachusetts, USA)
Material： Nature (London)  (Nature (Lond))
Volume： 485  Issue： 7399  Page： 502-506  Publication year： May. 24, 2012 
JST Material Number： D0193B  ISSN： 0028-0836  Document type： Article
Article type： 原著論文  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Thesaurus term： *Melanoma ,  human ,  nucleotide sequence ,  genome ,  *oncogene ,  Carcinogenesis ,  Point Mutation ,  ultraviolet irradiation ,  malignant melanoma ,  metastasis
Semi thesaurus term： *PREX2遺伝子 ,  Metastatic melanoma

JST classification (2)： Genetic variation  (EC01030Y) ,  Carcinogenic mechanisms and factors  (GE02020C)

Terms in the title (5)： 黒色腫 ,  ゲノム ,  塩基配列 ,  解読 ,  変異