Art

J-GLOBAL ID：201202237017596656   Reference number：12A1602335

Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease

宿主と微生物の相互作用が炎症性腸疾患の遺伝学的構造を形作る

Author (40)： JOSTINS Luke (Wellcome Trust Genome Campus, Hinxton, Cambridge, GBR) ,  ANDERSON Carl A. (Wellcome Trust Genome Campus, Hinxton, Cambridge, GBR) ,  BARRETT Jeffrey C. (Wellcome Trust Genome Campus, Hinxton, Cambridge, GBR) ,  RIPKE Stephan (Harvard Medical School, Massachusetts, USA) ,  DALY Mark J. (Harvard Medical School, Massachusetts, USA) ,  RIPKE Stephan (Broad Inst. of MIT and Harvard, Massachusetts, USA) ,  DALY Mark J. (Broad Inst. of MIT and Harvard, Massachusetts, USA) ,  WEERSMA Rinse K. (Univ. Groningen, Groningen, NLD) ,  DE JONG Dirk (Univ. Groningen, Groningen, NLD) ,  DUERR Richard H. (Univ. Pittsburgh School of Medicine, Pennsylvania, USA) ,  BAIDOO Leonard (Univ. Pittsburgh School of Medicine, Pennsylvania, USA) ,  FRANSEN Karin (Univ. Pittsburgh School of Medicine, Pennsylvania, USA) ,  REGUEIRO Miguel (Univ. Pittsburgh School of Medicine, Pennsylvania, USA) ,  DUERR Richard H. (Univ. Pittsburgh Graduate School of Public Health, Pennsylvania, USA) ,  MCGOVERN Dermot P. (F. Widjaja Foundation Inflammatory Bowel and Immunobiology Res. Inst., California, USA) ,  TARGAN Stephan R. (F. Widjaja Foundation Inflammatory Bowel and Immunobiology Res. Inst., California, USA) ,  TAYLOR Kent D. (F. Widjaja Foundation Inflammatory Bowel and Immunobiology Res. Inst., California, USA) ,  MCGOVERN Dermot P. (Cedars-Sinai Medical Center, California, USA) ,  HARITUNIANS Talin (Cedars-Sinai Medical Center, California, USA) ,  ROTTER Jerome I. (Cedars-Sinai Medical Center, California, USA) ,  TAYLOR Kent D. (Cedars-Sinai Medical Center, California, USA) ,  HUI Ken Y. (Yale School of Medicine, Connecticut, USA) ,  CHO Judy H (Yale School of Medicine, Connecticut, USA) ,  LEE James C. (Univ. Cambridge, Cambridge, GBR) ,  PARKES Miles (Univ. Cambridge, Cambridge, GBR) ,  SCHUMM L. Philip (Univ. Chicago, Illinois, USA) ,  SHARMA Yashoda (Yale School of Medicine, Connecticut, USA) ,  NING Kaida (Yale School of Medicine, Connecticut, USA) ,  ABRAHAM Clara (Yale School of Medicine, Connecticut, USA) ,  HEDL Matija (Yale School of Medicine, Connecticut, USA) ,  ESSERS Jonah (Harvard Medical School, Massachusetts, USA) ,  MITROVIC Mitja (Univ. Maribor, Maribor, SVN) ,  POTOCNIK Uros (Univ. Maribor, Maribor, SVN) ,  MITROVIC Mitja (Univ. Medical Center Groningen, Groningen, NLD) ,  CLEYNEN Isabelle (KU Leuven, Leuven, BEL) ,  VERMEIRE Severine (KU Leuven, Leuven, BEL) ,  THEATRE Emilie (Univ. Liege, Liege, BEL) ,  GEORGES Michel (Univ. Liege, Liege, BEL) ,  LOUIS Edouard (Univ. Liege, Liege, BEL) ,  SPAIN Sarah L. (King’s Coll. London School of Medicine, London, GBR)
Material： Nature (London)  (Nature (Lond))
Volume： 491  Issue： 7422  Page： 119-124  Publication year： Nov. 01, 2012 
JST Material Number： D0193B  ISSN： 0028-0836  Document type： Article
Article type： 原著論文  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Thesaurus term： human ,  ulcerative colitis ,  Crohn Disease ,  genetic technique ,  Phenotype ,  meta-analysis ,  bacterial infection (phenomenon) ,  gene expression ,  risk factor ,  case control study ,  *gene locus ,  host ,  *intestinal disease ,  Genome-Wide Association Study ,  network analysis ,  *Inflammatory Bowel Diseases ,  Mycobacterium ,  Inflammation ,  ulcer ,  symptom ,  colitis (large intestine) ,  Enteritis ,  molecular genetic phenomenon ,  microorganism ,  Actinomycetales
Semi thesaurus term： Mycobacterium ,  Genome-Wide Association Study

JST classification (1)： Genetic variation  (EC01030Y)

Terms in the title (5)： 宿主 ,  微生物 ,  相互作用 ,  炎症性腸疾患 ,  遺伝学的構造