Art

J-GLOBAL ID：201202237316476551   Reference number：12A0176405

Discovery and Characterization of Small Molecule Inhibitors of the BET Family Bromodomains

BET族ブロモドメインの小分子阻害剤の発見及び特性評価

Author (30)： CHUNG Chun-wa (Molecular Discovery Res., Stevenage, GBR) ,  COSTE Herve (Lipid Metabolism Discovery Performance Unit, Les Ulis, FRA) ,  WHITE Julia H. (Molecular Discovery Res., Stevenage, GBR) ,  MIRGUET Olivier (Lipid Metabolism Discovery Performance Unit, Les Ulis, FRA) ,  WILDE Jonathan (Molecular Discovery Res., Stevenage, GBR) ,  GOSMINI Romain L. (Lipid Metabolism Discovery Performance Unit, Les Ulis, FRA) ,  DELVES Chris (Molecular Discovery Res., Stevenage, GBR) ,  MAGNY Sylvie M. (Lipid Metabolism Discovery Performance Unit, Les Ulis, FRA) ,  WOODWARD Robert (Molecular Discovery Res., Stevenage, GBR) ,  HUGHES Stephen A. (Molecular Discovery Res., Stevenage, GBR) ,  BOURSIER Eric V. (Lipid Metabolism Discovery Performance Unit, Les Ulis, FRA) ,  FLYNN Helen (Molecular Discovery Res., Stevenage, GBR) ,  BOUILLOT Anne M. (Lipid Metabolism Discovery Performance Unit, Les Ulis, FRA) ,  BAMBOROUGH Paul (Molecular Discovery Res., Stevenage, GBR) ,  BRUSQ Jean-Marie G. (Lipid Metabolism Discovery Performance Unit, Les Ulis, FRA) ,  GELLIBERT Francoise J. (Lipid Metabolism Discovery Performance Unit, Les Ulis, FRA) ,  JONES Emma J. (Molecular Discovery Res., Stevenage, GBR) ,  RIOU Alizon M. (Lipid Metabolism Discovery Performance Unit, Les Ulis, FRA) ,  HOMES Paul (Molecular Discovery Res., Stevenage, GBR) ,  MARTIN Sandrine L. (Lipid Metabolism Discovery Performance Unit, Les Ulis, FRA) ,  UINGS Iain J. (Discovery Performance Unit, Stevenage, GBR) ,  TOUM Jerome (Lipid Metabolism Discovery Performance Unit, Les Ulis, FRA) ,  CLEMENT Catherine A. (Lipid Metabolism Discovery Performance Unit, Les Ulis, FRA) ,  BOULLAY Anne-Benedicte (Lipid Metabolism Discovery Performance Unit, Les Ulis, FRA) ,  GRIMLEY Rachel L. (Molecular Discovery Res., Stevenage, GBR) ,  BLANDEL Florence M. (Lipid Metabolism Discovery Performance Unit, Les Ulis, FRA) ,  PRINJHA Rab K. (Discovery Performance Unit, Stevenage, GBR) ,  LEE Kevin (Discovery Performance Unit, Stevenage, GBR) ,  KIRILOVSKY Jorge (Lipid Metabolism Discovery Performance Unit, Les Ulis, FRA) ,  NICODEME Edwige (Lipid Metabolism Discovery Performance Unit, Les Ulis, FRA)
Material： Journal of Medicinal Chemistry  (J Med Chem)
Volume： 54  Issue： 11  Page： 3827-3838  Publication year： Jun. 09, 2011 
JST Material Number： D0102A  ISSN： 0022-2623  CODEN： JMCMAR  Document type： Article
Country of issue： United States (USA)  Language： ENGLISH (EN)

Terms in the title (4)： ブロモドメイン ,  小分子阻害剤 ,  発見 ,  特性評価