Art

J-GLOBAL ID：201202240092814945   Reference number：12A0292186

A Continual Reassessment Method that Adaptively Changes the Prior Distribution According to the Initial Cohort Observation

初期コホートの観察に従った事前分布を適切に変更させる連続再評価法

Author (3)： ASAKAWA Takashi (Chugai Pharmaceutical Co., Ltd., Tokyo, JPN) ,  ISHIZUKA Naoki (National Center for Global Health and Medicine, Tokyo, JPN) ,  HAMADA Chikuma (Tokyo Univ. Sci., Tokyo, JPN)
Material： 臨床薬理  (Japanese Journal of Clinical Pharmacology and Therapeutics)
Volume： 43  Issue： 1  Page： 21-28  Publication year： Jan. 31, 2012 
JST Material Number： F0384B  ISSN： 0388-1601  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： toxicity ,...
Semi thesaurus term： dose-limiting toxicity ,...

Register(free) or Log In to access     To see more with JDream III (charged).   {{ this.onShowAbsJLink("http://jdream3.com/lp/jglobal/index.html?docNo=12A0292186&from=J-GLOBAL&jstjournalNo=F0384B") }}

JST classification (2)： Research and development  (GU01040N) ,  Research and development  (GA01030U)

Reference (11)：

• O'QUIGLEY, J. Continual reassessment method : a practical design for phase I clinical trials in cancer. Biometrics. 1990, 46, 1, 33-48
• WARREN, KE. Phase I trial of lenalidomide in pediatric patients with recurrent, refractory, or progressive primary CNS tumors : Pediatric Brain Tumor Consortium study PBTC-018. J Clin Oncol. 2011, 29, 3, 324-329
• RUAN, J. Bortezomib plus CHOP-rituximab for previously untreated diffuse large B-cell lymphoma and mantle cell lymphoma. J Clin Oncol. 2011, 29, 6, 690-697
• GANDHI, L. Phase I study of Navitoclax (ABT-263), a novel Bcl-2 family inhibitor, in patients with small-cell lung cancer and other solid tumors. J Clin Oncol. 2011, 29, 7, 909-916
• MORITA, S. Application of a continual reassessment method to a phase I clinical trial of capecitabine in combination with cyclophosphamide and epirubicin (CEX) for inoperable or recurrent breast cancer. Jpn J Clin Oncol. 2004, 34, 2, 104-106

Terms in the title (5)： 初期 ,  コホート ,  観察 ,  事前分布 ,  評価法