Art

J-GLOBAL ID：201202240908611797   Reference number：12A1050761

Amelioration by the Natural Polyamine Spermine of Cartilage and Bone Destruction in Rats With Collagen-Induced Arthritis

コラーゲン誘導関節炎ラットでの軟骨と骨破壊の天然ポリアミン,スペルミンによる軽減

Author (6)： IEZAKI Takashi (Lab. of Molecular Pharmacology, Div. of Pharmaceutical Sciences, Kanazawa Univ. Graduate School of Natural Sci. and ...) ,  HINOI Eiichi (Lab. of Molecular Pharmacology, Div. of Pharmaceutical Sciences, Kanazawa Univ. Graduate School of Natural Sci. and ...) ,  YAMAMOTO Tomomi (Lab. of Molecular Pharmacology, Div. of Pharmaceutical Sciences, Kanazawa Univ. Graduate School of Natural Sci. and ...) ,  ISHIURA Ryo (Lab. of Molecular Pharmacology, Div. of Pharmaceutical Sciences, Kanazawa Univ. Graduate School of Natural Sci. and ...) ,  OGAWA Shinya (Lab. of Molecular Pharmacology, Div. of Pharmaceutical Sciences, Kanazawa Univ. Graduate School of Natural Sci. and ...) ,  YONEDA Yukio (Lab. of Molecular Pharmacology, Div. of Pharmaceutical Sciences, Kanazawa Univ. Graduate School of Natural Sci. and ...)
Material： Journal of Pharmacological Sciences  (J Pharmacol Sci)
Volume： 119  Issue： 1  Page： 107-111 (J-STAGE)  Publication year： 2012 
JST Material Number： G0813A  ISSN： 1347-8613  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *Arthritis ,...
Semi thesaurus term： rheumatoid arthritis ,...

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JST classification (1)： Basic medicine on musculoskeletal system  (GG01020B)

Substance index (2)： Spermine ,  Spermidine

Reference (14)：

• 1 Hinoi E, Ohashi R, Miyata S, Kato Y, Iemata M, Hojo H, et al. Excitatory amino acid transporters expressed by synovial fibroblasts in rats with collagen-induced arthritis. Biochem Pharmacol. 2005;70:1744–1755.
• 2 Waldburger JM, Firestein GS. Garden of therapeutic delights: new targets in rheumatic diseases. Arthritis Res Ther. 2009;11:206.
• 3 Igarashi K, Kashiwagi K. Modulation of cellular function by polyamines. Int J Biochem Cell Biol. 2010;42:39–51.
• 4 Morrison LD, Kish SJ. Brain polyamine levels are altered in Alzheimer’s disease. Neurosci Lett. 1995;197:5–8.
• 5 Turchanowa L, Rogozkin VA, Milovic V, Feldkoren BI, Caspary WF, Stein J. Influence of physical exercise on polyamine synthesis in the rat skeletal muscle. Eur J Clin Invest. 2000;30:72–78.

Terms in the title (6)： コラーゲン誘導関節炎 ,  ラット ,  軟骨 ,  骨破壊 ,  ポリアミン ,  スペルミン