Art

J-GLOBAL ID：201202244280571079   Reference number：12A0684026

Valproic Acid Inhibits Angiogenesis In Vitro and Glioma Angiogenesis In Vivo in the Brain

バルプロ酸はin vitroでの血管新生ならびに脳におけるin vivoでの神経膠腫の血管新生を阻害する

Author (7)： OSUKA Satoru (Dep. of Neurosurgery, Inst. of Clinical Medicine, Graduate School of Comprehensive Human Sciences, Univ. of Tsukuba) ,  OSUKA Satoru (Res. Fellow of the Japan Soc. for the Promotion of Sci.) ,  TAKANO Shingo (Dep. of Neurosurgery, Inst. of Clinical Medicine, Graduate School of Comprehensive Human Sciences, Univ. of Tsukuba) ,  WATANABE Shinya (Dep. of Neurosurgery, Inst. of Clinical Medicine, Graduate School of Comprehensive Human Sciences, Univ. of Tsukuba) ,  ISHIKAWA Eiichi (Dep. of Neurosurgery, Inst. of Clinical Medicine, Graduate School of Comprehensive Human Sciences, Univ. of Tsukuba) ,  YAMAMOTO Tetsuya (Dep. of Neurosurgery, Inst. of Clinical Medicine, Graduate School of Comprehensive Human Sciences, Univ. of Tsukuba) ,  MATSUMURA Akira (Dep. of Neurosurgery, Inst. of Clinical Medicine, Graduate School of Comprehensive Human Sciences, Univ. of Tsukuba)
Material： Neurologia Medico-Chirurgica  (神経外科)
Volume： 52  Issue： 4  Page： 186-193 (J-STAGE)  Publication year： 2012 
JST Material Number： Z0762A  ISSN： 0470-8105  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *enzyme inhibitor ,...
Semi thesaurus term： VEGF

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JST classification (2)： Basic research of antitumor(=antineoplastic)drugs  (GW16010A) ,  Basic research of enzyme preparations and enzyme inhibitor preparations  (GW21010W)

Substance index (1)： Valproic acid

Reference (31)：

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• CHAVEZ-BLANCO, A. Antineoplastic effects of the DNA methylation inhibitor hydralazine and the histone deacetylase inhibitor valproic acid in cancer cell lines. Cancer Cell Int. 2006, 6, 2

Terms in the title (5)： バルプロ酸 ,  血管新生 ,  脳 ,  神経膠腫 ,  阻害