Art

J-GLOBAL ID：201202265660991477   Reference number：12A1681205

Reinvestigation of Drugs and Chemicals as Aquaporin-1 Inhibitors Using Pressure-Induced Hemolysis in Human Erythrocytes

ヒト赤血球において圧力誘起溶血を用いるアクアポリン1阻害剤としての薬物及び化学品の再検討

Author (4)： YAMAGUCHI Takeo (Dep. of Chemistry, Fac. of Sci., Fukuoka Univ.) ,  IWATA Yohei (Dep. of Chemistry, Fac. of Sci., Fukuoka Univ.) ,  MIURA Shingo (Dep. of Chemistry, Fac. of Sci., Fukuoka Univ.) ,  KAWADA Kazumasa (Dep. of Chemistry, Fac. of Sci., Fukuoka Univ.)
Material： Biological and Pharmaceutical Bulletin  (Biological & Pharmaceutical Bulletin)
Volume： 35  Issue： 11  Page： 2088-2091 (J-STAGE)  Publication year： 2012 
JST Material Number： S0989A  ISSN： 0918-6158  CODEN： BPBLEO  Document type： Article
Article type： 短報  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *Hemolysis ,...
Semi thesaurus term： *aquaporin ,...

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JST classification (2)： Transport of cell membrane  (EF04020R) ,  Biological function  (EB03040U)

Substance index (3)： Acetazolamide ,  Dimethyl sulfoxide ,  Tetraethylammonium

Reference (28)：

• 1) Verkman AS. Aquaporins at a glance. J. Cell Sci., 124, 2107–2112 (2011).
• 2) Preston GM, Jung JS, Guggino WB, Agre P. The mercury-sensitive residue at cysteine 189 in the CHIP28 water channel. J. Biol. Chem., 268, 17–20 (1993).
• 3) Preston GM, Carroll TP, Guggino WB, Agre P. Appearance of water channels in Xenopus oocytes expressing red cell CHIP28 protein. Science, 256, 385–387 (1992).
• 4) Brooks HL, Regan JW, Yool AJ. Inhibition of aquaporin-1 water permeability by tetraethylammonium: Involvement of the loop E pore region. Mol. Pharmacol., 57, 1021–1026 (2000).
• 5) Yang B, Kim JK, Verkman AS. Comparative efficacy of HgCl₂ with candidate aquaporin-1 inhibitors DMSO, gold, TEA⁺ and acetazolamide. FEBS Lett., 580, 6679–6684 (2006).

Terms in the title (8)： ヒト ,  赤血球 ,  誘起 ,  溶血 ,  アクアポリン1 ,  阻害剤 ,  薬物 ,  化学品