Art

J-GLOBAL ID：201202268178215710   Reference number：12A0056409

Novel platelet activation receptor CLEC-2 from discovery to prospects

新規血小板活性化受容体CLEC-2 その発見から今後の展望まで

Author (3)： INOUE KATSUE (山梨大学大学院医学工学総合研究部臨床検査医学) ,  INOUE OSAMU (山梨大学大学院医学工学総合研究部臨床検査医学) ,  OZAKI YUKIO (山梨大学大学院医学工学総合研究部臨床検査医学)
Material： 日本血栓止血学会誌  (Japanese Journal of Thrombosis and Hemostasis)
Volume： 22  Issue： 6  Page： 348-362 (J-STAGE)  Publication year： 2011 
JST Material Number： L2757A  ISSN： 0915-7441  Document type： Article
Article type： 文献レビュー  Country of issue： Japan (JPN)  Language： JAPANESE (JA)

Thesaurus term： *cell adhesion receptor ,...
Semi thesaurus term： *CLEC2 ,...

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JST classification (1)： Receptors on cell membrane  (EF04030C)

Reference (86)：

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• SHIN, Y. Rhodocytin, a functional novel platelet agonist belonging to the heterodimeric C-type lectin family, induces platelet aggregation independently of glycoprotein Ib. Biochem Biophys Res Commun. 1998, 245, 741-745
• INOUE, K. Signal transduction pathways mediated by glycoprotein Ia/IIa in human platelets : comparison with those of glycoprotein VI. Biochem Biophys Res Commun. 1999, 256, 114-120
• SUZUKI-INOUE, K. Rhodocytin induces platelet aggregation by interacting with glycoprotein Ia/IIa (GPIa/IIa, Integrin alpha 2beta 1). Involvement of GPIa/IIa-associated src and protein tyrosine phosphorylation. J Biol Chem. 2001, 276, 1643-1652
• NAVDAEV, A. Aggretin, a heterodimeric C-type lectin from Calloselasma rhodostoma (malayan pit viper), stimulates platelets by binding to alpha 2beta 1 integrin and glycoprotein Ib, activating Syk and phospholipase Cgamma 2, but does not involve the glycoprotein VI/Fc receptor gamma chain collagen receptor. J Biol Chem. 2001, 276, 20882-20889

Terms in the title (5)： 血小板活性化 ,  受容体 ,  CLEC-2 ,  発見 ,  展望