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J-GLOBAL ID：201202268583567062   Reference number：12A0264594

Activation of AMP-activated protein kinase by MAPO1 and FLCN induces apoptosis triggered by alkylated base mismatch in DNA

MAPO1とFLCNによるAMP活性化蛋白質キナーゼの活性化がDNAのアルキル化塩基ミスマッチによって引き起こされたアポトーシスを誘導する

Author (9)： LIM Teik How (Dep. of Medical Biophysics and Radiation Biology, Fac. of Medical Sciences, Kyushu Univ., Fukuoka 812-8582, JPN) ,  FUJIKANE Ryosuke (Dep. of Physiological Sci. and Molecular Biology, Fukuoka Dental Coll., Fukuoka 814-0193, JPN) ,  SANO Shiori (Dep. of Physiological Sci. and Molecular Biology, Fukuoka Dental Coll., Fukuoka 814-0193, JPN) ,  SANO Shiori (Dep. of Odontology, Fukuoka Dental Coll., Fukuoka 814-0193, JPN) ,  SAKAGAMI Ryuji (Dep. of Odontology, Fukuoka Dental Coll., Fukuoka 814-0193, JPN) ,  NAKATSU Yoshimichi (Dep. of Medical Biophysics and Radiation Biology, Fac. of Medical Sciences, Kyushu Univ., Fukuoka 812-8582, JPN) ,  TSUZUKI Teruhisa (Dep. of Medical Biophysics and Radiation Biology, Fac. of Medical Sciences, Kyushu Univ., Fukuoka 812-8582, JPN) ,  SEKIGUCHI Mutsuo (Frontier Res. Center, Fukuoka Dental Coll., Fukuoka 814-0193, JPN) ,  HIDAKA Masumi (Dep. of Physiological Sci. and Molecular Biology, Fukuoka Dental Coll., Fukuoka 814-0193, JPN)
Material： DNA Repair
Volume： 11  Issue： 3  Page： 259-266  Publication year： Mar. 01, 2012 
JST Material Number： W1339A  ISSN： 1568-7864  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Thesaurus term： tumor suppressor protein ,  tumor suppressor gene ,  Proteins ,  *serine-threonine kinase ,  *Apoptosis ,  protein complex ,  alkylating agent ,  ether ,  nitrogen heterocyclic compound ,  nitrosamine ,  urea compound ,  *AMP-Activated Protein Kinases ,  BHD gene ,  folliculin ,  *Base Pair Mismatch ,  Signal Transduction ,  *base pair
Semi thesaurus term： *mismatched base pair ,  cellular signal transduction ,  MAPO1

JST classification (2)： Cell physiology in general  (EF02010S) ,  Molecular genetics in general  (EC02010J)

Substance index (2)： O6-Methylguanine ,  Methylnitrosourea

Terms in the title (9)： FLCN ,  AMP活性化蛋白質キナーゼ ,  活性化 ,  DNA ,  アルキル化 ,  塩基 ,  ミスマッチ ,  アポトーシス ,  誘導