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J-GLOBAL ID:201202271199526732   Reference number:12A1558578

ペプチドと血管力向上

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Material:
Volume: 54  Issue: 11  Page: 39-46  Publication year: Nov. 01, 2012 
JST Material Number: F0354A  ISSN: 0547-0277  Document type: Article
Article type: 解説  Country of issue: Japan (JPN)  Language: JAPANESE (JA)
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Biological function  ,  Basic research of vasoactive drugs and hypotensive drugs 
Reference (43):
  • 1) Kawasaki T., Seki E., Osajima M. et al.: Antihypertensive effect of Valyl-Tyrosine, a short chain peptide derived from sardine muscle hydrolyzate, on mild hypertensive subjects. J. Hum. Hypertens. 14: 519-523, 2000.
  • 2) Matsui T., Hayashi A., Tamaya K. et al.: Depressor effect induced by dipeptide, Val-Tyr, in hypertensive transgenic mice is due, in part, to the suppression of human circulating renin-angiotensin system. Clin. Exp. Pharm. Physiol. 30: 262-265, 2003.
  • 3) Okunishi H., Kawamoto T., Kurobe Y. et al.: Pathogenetic role of vascular angiotensin-converting enzyme in the spontaneously hypertensive rat. Clin. Exp. Pharm. Physiol. 18: 649-659, 1991
  • 4) Matsui T., Imamura M., Oka H. et al.: Tissue distribution of antihypertensive dipeptide, Val-Tyr, after its single oral administration to spontaneously hypertensive rats. J. Peptide. Sci. 10: 535-545, 2004.
  • 5) Matsui T., Wang Z., Tanaka M.: Vascular regulation by small peptide; BIOACTIVE NATURAL PRODUCTS Opportunities and Challenges in Medicinal Chemistry. Brahmachari G., Singapore, World Scientific, 201-221, 2011.
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