Inhibition of Ubiquitin Ligase F-box and WD Repeat Domain-containing 7α (Fbw7α) Causes Hepatosteatosis through Krueppel-like Factor 5 (KLF5)/Peroxisome Proliferator-activated Receptor γ2 (PPARγ2) Pathway but Not SREBP-1c Protein in Mice

KUMADAKI Shin; KARASAWA Tadayoshi; MATSUZAKA Takashi; EMA Masatsugu; NAKAGAWA Yoshimi; NAKAKUKI Masanori; SAITO Ryo; YAHAGI Naoya; IWASAKI Hitoshi; SONE Hirohito; TAKEKOSHI Kazuhiro; YATOH Shigeru; KOBAYASHI Kazuto; TAKAHASHI Akimitsu; SUZUKI Hiroaki; TAKAHASHI Satoru; YAMADA Nobuhiro; SHIMANO Hitoshi

Art

J-GLOBAL ID：201202276291382218 Reference number：12A0040184

Inhibition of Ubiquitin Ligase F-box and WD Repeat Domain-containing 7α (Fbw7α) Causes Hepatosteatosis through Krueppel-like Factor 5 (KLF5)/Peroxisome Proliferator-activated Receptor γ2 (PPARγ2) Pathway but Not SREBP-1c Protein in Mice

ユビキチンリガーゼF-ボックスおよびWDリピートドメイン含有7α(Fbw7α)の阻害はマウスにおいてSREBP-1c蛋白質でなくKruppel様因子5(KLF5)/ペルオキシソーム増殖活性化受容体γ2(PPARγ2)を通した脂肪過多症を誘発する

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Material：
Volume： 286 Issue： 47 Page： 40835-40846 Publication year： Nov. 25, 2011
JST Material Number： E0038A ISSN： 0021-9258 CODEN： JBCHA3 Document type： Article
Article type：原著論文 Country of issue： United States (USA) Language： ENGLISH (EN)

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Metabolism in general , Biological function

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