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J-GLOBAL ID：201202286368642981   Reference number：12A0520752

Identification of new ALK and RET gene fusions from colorectal and lung cancer biopsies

がん:結腸直腸がんおよび肺がん生検標本におけるALK遺伝子およびRET遺伝子の新規融合体の同定

Author (33)： LIPSON Doron (Foundation Medicine, Massachusetts, USA) ,  YELENSKY Roman (Foundation Medicine, Massachusetts, USA) ,  OTTO Geoff (Foundation Medicine, Massachusetts, USA) ,  PARKER Alex (Foundation Medicine, Massachusetts, USA) ,  JAROSZ Mirna (Foundation Medicine, Massachusetts, USA) ,  CURRAN John A (Foundation Medicine, Massachusetts, USA) ,  BALASUBRAMANIAN Sohail (Foundation Medicine, Massachusetts, USA) ,  BLOOM Troy (Foundation Medicine, Massachusetts, USA) ,  BRENNAN Kristina W (Foundation Medicine, Massachusetts, USA) ,  DONAHUE Amy (Foundation Medicine, Massachusetts, USA) ,  DOWNING Sean R (Foundation Medicine, Massachusetts, USA) ,  FRAMPTON Garrett M (Foundation Medicine, Massachusetts, USA) ,  GARCIA Lazaro (Foundation Medicine, Massachusetts, USA) ,  JUHN Frank (Foundation Medicine, Massachusetts, USA) ,  MITCHELL Kathy C (Foundation Medicine, Massachusetts, USA) ,  WHITE Emily (Foundation Medicine, Massachusetts, USA) ,  WHITE Jared (Foundation Medicine, Massachusetts, USA) ,  ZWIRKO Zac (Foundation Medicine, Massachusetts, USA) ,  ROSS Jeffrey S (Foundation Medicine, Massachusetts, USA) ,  CRONIN Maureen T (Foundation Medicine, Massachusetts, USA) ,  STEPHENS Philip J (Foundation Medicine, Massachusetts, USA) ,  CAPELLETTI Marzia (Dana-Farber Cancer Inst., Massachusetts, USA) ,  ERCAN Dalia (Dana-Farber Cancer Inst., Massachusetts, USA) ,  JAENNE Pasi A (Dana-Farber Cancer Inst., Massachusetts, USA) ,  PERETZ Tamar (Hadassah-Hebrew Univ. Medical Center, Jerusalem, ISR) ,  NECHUSHTAN Hovav (Hadassah-Hebrew Univ. Medical Center, Jerusalem, ISR) ,  SOUSSAN-GUTMAN Lior (Oncotest-Teva Pharmaceutical Ind., Petach Tikva, ISR) ,  KIM Jhingook (Sungkyunkwan Univ. School of Medicine, Seoul, KOR) ,  SASAKI Hidefumi (Nagoya City Univ. Graduate School of Medical Sci., Nagoya, JPN) ,  KIM Hyeong Ryul (Univ. Ulsan Coll. of Medicine, Seoul, KOR) ,  PARK Seung-il (Univ. Ulsan Coll. of Medicine, Seoul, KOR) ,  SHEEHAN Christine E (Albany Medical Center, New York, USA) ,  ROSS Jeffrey S (Albany Medical Center, New York, USA)
Material： Nature Medicine  (Nat Med)
Volume： 18  Issue： 3  Page： 382-384  Publication year： Mar. 2012 
JST Material Number： W0636A  ISSN： 1078-8956  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Thesaurus term： *colonic neoplasm ,  *rectal neoplasm ,  *lung tumor ,  biological sample ,  sample(statistics) ,  gene ,  oncogene ,  *gene fusion ,  fixation of biological sample ,  biomedical tissue ,  *nucleotide sequence ,  *molecular genetic phenomenon ,  *adenocarcinoma ,  *screening(inspection) ,  drug sensitivity ,  enzyme inhibitor
Semi thesaurus term： *colorectal cancer ,  resected specimen ,  ALK gene ,  ret gene ,  formalin fixation ,  Paraffin-embedded tissue ,  *genome abnormality ,  *Adenocarcinoma lung ,  kinase inhibitor

JST classification (4)： Chemistry,biochemistry and pathology of tumors(=neoplasms)  (GE02030N) ,  Tumors(=neoplasms)of digestive system  (GH04000D) ,  Tumors(=neoplasms)of respiratory system  (GI04000G) ,  Molecular genetics in general  (EC02010J)

Terms in the title (9)： がん ,  結腸直腸がん ,  肺がん ,  生検 ,  標本 ,  ALK遺伝子 ,  RET遺伝子 ,  融合 ,  同定