Art

J-GLOBAL ID：201202296344316337   Reference number：12A0430412

Polyvalent Immunostimulatory Nanoagents with Self-Assembled CpG Oligonucleotide-Conjugated Gold Nanoparticles

自己集合CpGオリゴヌクレオチド結合金ナノ粒子と一体となった多価免疫賦活性ナノ薬剤

Author (9)： WEI Min (Shanghai Inst. Applied Physics, Chinese Acad. Sci., Shanghai, CHN) ,  CHEN Nan (Shanghai Inst. Applied Physics, Chinese Acad. Sci., Shanghai, CHN) ,  LI Jiang (Shanghai Inst. Applied Physics, Chinese Acad. Sci., Shanghai, CHN) ,  YIN Min (Shanghai Inst. Applied Physics, Chinese Acad. Sci., Shanghai, CHN) ,  LIANG Le (Shanghai Inst. Applied Physics, Chinese Acad. Sci., Shanghai, CHN) ,  HE Yao (Shanghai Inst. Applied Physics, Chinese Acad. Sci., Shanghai, CHN) ,  SONG Haiyun (Shanghai Inst. Biological Sci., Chinese Acad. Sci., Shanghai, CHN) ,  FAN Chunhai (Shanghai Inst. Applied Physics, Chinese Acad. Sci., Shanghai, CHN) ,  HUANG Qing (Shanghai Inst. Applied Physics, Chinese Acad. Sci., Shanghai, CHN)
Material： Angewandte Chemie. International Edition  (Angewandte Chemie. International Edition in English)
Volume： 51  Issue： 5  Page： 1202-1206  Publication year： 2012 
JST Material Number： H0127B  ISSN： 1433-7851  CODEN： ACIEAY  Document type： Article
Article type： 短報  Country of issue： Germany, Federal Republic of (DEU)  Language： ENGLISH (EN)

Thesaurus term： nano particle ,  drug carrier ,  *drug delivery system ,  nanostructure ,  *oligonucleotide ,  self assembly ,  immunopotentiative action ,  *immunopotentiator ,  substitution reaction ,  addition reaction ,  RAW264.7 cell ,  cytotoxicity ,  fluorometry (measurement) ,  chromophore ,  TNF alpha ,  interleukin 6 ,  interleukin 10 ,  DNA binding protein ,  Toll like receptor ,  thiolation ,  gold nanoparticle ,  *CpG-oligo DNA ,  Toll-Like Receptor 9 ,  fluorophore
Semi thesaurus term： *CpG oligodeoxynucleotide ,  TLR9 ,  fluorophore

JST classification (3)： Basic research of immunotherapeutic agents and blood preparations  (GW22010D) ,  Basic biopharmacy  (GY01021U) ,  Nucleic acids in general  (EB04010U)

Terms in the title (8)： 自己集合 ,  CPG ,  オリゴヌクレオチド ,  金ナノ粒子 ,  多価 ,  免疫 ,  賦活 ,  薬剤