Art

J-GLOBAL ID：201202297630323932   Reference number：12A0539122

Alzheimer Mechanisms and Therapeutic Strategies

アルツハイマー病機構と治療戦略

Author (4)： HUANG Yadong (Gladstone Inst. of Neurological Disease, San Francisco, CA 94158, USA) ,  HUANG Yadong (Dep. of Neurology, Univ. of California, San Francisco, San Francisco, CA 94158, USA) ,  MUCKE Lennart (Gladstone Inst. of Neurological Disease, San Francisco, CA 94158, USA) ,  MUCKE Lennart (Dep. of Neurology, Univ. of California, San Francisco, San Francisco, CA 94158, USA)
Material： Cell (Cambridge, Mass.)  (Cell (Camb. Mass.))
Volume： 148  Issue： 6  Page： 1204-1222  Publication year： Mar. 16, 2012 
JST Material Number： A0707B  ISSN： 0092-8674  Document type： Article
Article type： 文献レビュー  Country of issue： United States (USA)  Language： ENGLISH (EN)

Thesaurus term： *Alzheimer Disease ,  *therapeutic planning ,  senile change ,  nervous system disease ,  tau protein ,  therapy ,  mechanism ,  amyloid beta-protein ,  apo E ,  neurotoxicity ,  experimental disease ,  transgenic mouse ,  post-translational modification ,  intermolecular interaction ,  cholinesterase inhibitor ,  drug therapy ,  species specificity ,  alicyclic compound ,  bridged compound ,  primary amine ,  Individualized Medicine ,  alpha-Synuclein ,  Systems Biology ,  molecular mechanism ,  protein-protein interaction ,  Apolipoprotein E4 ,  Neurofibrillary Tangle ,  Amyloid ,  glycoprotein ,  animal protein
Semi thesaurus term： tailor-made medical treatment ,  Nerve Degeneration ,  apoE4 ,  neurofibrillary tangle

JST classification (4)： Central nervous system  (EJ12030F) ,  Nervous system diseases  (GN03000O) ,  Metabolic diseases,nutritional diseases in general.  (GD05010J) ,  Biological function  (EB03040U)

Substance index (1)： Memantine

Terms in the title (2)： アルツハイマー病 ,  治療戦略