Rchr
J-GLOBAL ID:201301002467394200   Update date: Mar. 04, 2021

Adachi Mimi

アダチ ミミ | Adachi Mimi
Affiliation and department:
Homepage URL  (1): http://kaken.nii.ac.jp/d/r/10323693.ja.html
Research field  (6): Cell biology ,  Molecular biology ,  Medical biochemistry ,  Medical biochemistry ,  Metabolism and endocrinology ,  Cardiology
Research keywords  (31): cyclin D1 ,  epigenetics ,  cellular senescence ,  aging ,  細胞増殖 ,  サイクリンD1 ,  心筋細胞 ,  p27 ,  増殖 ,  ユビキチン化 ,  p27^<kip1> ,  miRNA ,  ヘテロクロマチン ,  核移行 ,  老化 ,  CDK ,  心筋再生 ,  skp2 ,  サイクリン ,  細胞周期 ,  ヒストン ,  siRNA ,  p27kip1 ,  TGFβ ,  細胞死 ,  転写仲介因子 ,  クロマチン構造 ,  p300遺伝子 ,  口腔癌 ,  ブロモドメイン ,  癌抑制遺伝子
Research theme for competitive and other funds  (9):
  • 2019 - 2022 糖質コルチコイド制御による、老化のコントロールを目指す研究
  • 2015 - 2018 加齢による糖質コルチコイド合成系の変化と老化への影響の解析
  • 2011 - 2014 老化組織におけるヘテロクロマチン構造の解析と新規バイオマーカーの探索
  • 2007 - 2008 細胞周期制御因子による心筋再生療法の開発を目指した研究
  • 2005 - 2006 心筋再分裂誘導の分子機構と再生治療への応用に関する研究
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Papers (64):
  • Takahiro Kikuyama, Takao Susa, Mimi Tamamori-Adachi, Masayoshi Iizuka, Miho Akimoto, Hiroko Okinaga, Yoshihide Fujigaki, Shunya Uchida, Shigeru Shibata, Tomoki Okazaki. 25(OH)D3 stimulates the expression of vitamin D target genes in renal tubular cells when Cyp27b1 is abrogated. The Journal of steroid biochemistry and molecular biology. 2020. 199. 105593-105593
  • Takao Susa, Masayoshi Iizuka, Hiroko Okinaga, Mimi Tamamori-Adachi, Tomoki Okazaki. Without 1α-hydroxylation, the gene expression profile of 25(OH)D3 treatment overlaps deeply with that of 1,25(OH)2D3 in prostate cancer cells. Scientific Reports. 2018. 8. 1. 9024
  • Tamamori-Adachi M, Koga A, Susa T, Fujii H, Tsuchiya M, Okinaga H, Hisaki H, Iizuka M, Kitajima S, Okazaki T. DNA damage response induced by Etoposide promotes steroidogenesis via GADD45A in cultured adrenal cells. Scientific reports. 2018. 8. 1. 9636
  • Masayoshi Iizuka, Takao Susa, Mimi Tamamori-Adachi, Hiroko Okinaga, Tomoki Okazaki. Intrinsic ubiquitin E3 ligase activity of histone acetyltransferase Hbo1 for estrogen receptor alpha. PROCEEDINGS OF THE JAPAN ACADEMY SERIES B-PHYSICAL AND BIOLOGICAL SCIENCES. 2017. 93. 7. 498-510
  • Kosuke Uchida, Yuji Tanaka, Hitoshi Ichikawa, Masato Watanabe, Sachiyo Mitani, Koji Morita, Hiroko Fujii, Mayumi Ishikawa, Gen Yoshino, Hiroko Okinaga, et al. An Excess of CYP24A1, Lack of CaSR, and a Novel lncRNA Near the PTH Gene Characterize an Ectopic PTH-Producing Tumor. Journal of the Endocrine Society. 2017. 1. 6. 691-711
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MISC (20):
  • 諏佐 崇生, 飯塚 眞由, 安達 三美, 岡崎 具樹. ヒト前立腺癌LNCaP細胞における25(OH)D3のビタミンD3活性の評価. 日本内分泌学会雑誌. 2018. 94. 1. 369-369
  • Hiroko Fujii, Mimi Tamamori-Adachi, Takao Susa, Masayoshi Iizuka, Yuji Tanaka, Tomoki Okazaki. Marked Cortisol Production By Intracrine ACTH in Gip-Treated Cultured Adrenal Cells in Which Gip Receptor Was Exogenously Introduced. ENDOCRINE REVIEWS. 2014. 35. 3
  • Takao Susa, Reina Ikaga, Takashi Kajitani, Masayoshi Iizuka, Mimi Tamamori-Adachi, Tomoki Okazaki. Aberrant, but Physiological, Interactions Between the Non-Mutated Androgen Receptor and E2 in Several Sex Hormone-Responsive Cancer Cells. ENDOCRINE REVIEWS. 2014. 35. 3
  • Takahisa Matsuda, Pelyong Zhai, Chull Hong, Shumin Gao, Bin Tian, Kazumichi Goto, Mimi Tamamori-Adachi, Hiromitsu Takagi, Junichi Sadoshima. Serine 21 Phosphorylation of GSK-3 alpha Mediates Myocyte Proliferation through CyclinD1/E2F Pathway under Pressure Overload. CIRCULATION. 2008. 118. 18. S327-S327
  • Yasuhiro Maejima, Mimi Tamamori-Adachi, Kazuhiko Yamada, Susumu Adachi, Shigetaka Kitajima, Mitsuaki Isobe. Important Role of Basic Fibroblast Growth Factor Signaling and p27kip1 in Adult Cardiomyocyte Cell Cycle Regulation. CIRCULATION. 2008. 118. 18. S429-S429
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Books (8):
  • 実験医学2013年12月増刊号 老化・寿命研究の最前線
    羊土社 2013
  • 心筋症を識る・診る・治す
    文光堂 2007
  • キーワードで理解する細胞周期イラストマップ
    羊土社 2005
  • 分子細胞治療
    先端医学社 2004
  • 発生における細胞増殖制御
    シュプリンガー・フェアラーク東京 2004
more...
Education (5):
  • 1992 - 1996 Tokyo Medical and Dental University PhD.
  • 1992 - 1996 Tokyo Medical and Dental University
  • 1996 - 医学博士
  • 1984 - 1990 Tokyo Medical and Dental University M.D.
  • 1984 - 1990 Tokyo Medical and Dental University School of Medicine
Professional career (1):
  • 医学博士 (東京医科歯科大学)
Work history (18):
  • 2018/12 - 現在 Teikyo University School of Medicine Department of Biochemistry Professor
  • 2018/12 - 現在 Teikyo University School of Medicine
  • 2013/04 - 2018/11 Teikyo University School of Medicine Department of Biochemistry Associate Professor
  • 2013/04 - 2018/11 Teikyo University School of Medicine
  • 2010/04 - 2013/03 Teikyo University School of Medicine Department of Biochemistry Lecturer
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Awards (1):
  • 2004/04 - 東京医科歯科大学 東京医科歯科大学研究奨励賞
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